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New standardized cystatin C and creatinine GFR equations in children validated with inulin clearance

This study compares glomerular filtration rate (GFR) equations in children based on standardized cystatin C (CYSC) and creatinine (CREA) and their combinations with renal clearance of inulin (C-inulin). A total of 220 children with different renal disorders were referred for C-inulin (median 84 ml/min/1.73 m(2)). Bias, precision (interquartile range, IQR), and accuracy (percentage of estimates +/-

Coherent V-Band Pulse Generator for Impulse Radio BPSK

A coherent pulse generator for implementation in an impulse radio system is presented. It accurately transforms a 12.5 GHz square wave input signal to 33 ps long 60 GHz pulses. The wavelets are generated through direct conversion from base-band to 60 GHz by switching a negative differential conductance oscillator on and off. The slope of the input signal determines the phase, which is either I+ or

Availability of exercise facilities and physical activity in 2,037 adults: cross-sectional results from the Swedish neighborhood and physical activity (SNAP) study

Background: Exercise facilities may have the potential to promote physical activity among residents, and to support an active lifestyle throughout the year. We investigated the association between objectively assessed availability of exercise facilities and objectively assessed physical activity outcomes, and whether time of year had a modifying effect on these associations. Methods: A total of 2,

Increasing thermoelectric performance using coherent transport

We show that coherent electron transport through zero-dimensional systems can be used to tailor the shape of the system's transmission function. This quantum-engineering approach can be used to enhance the performance of quantum dots or molecules in thermal-to-electric power conversion. Specifically, we show that electron interference in a two-level system can substantially improve the maximum the

Probing the Wurtzite Conduction Band Structure Using State Filling in Highly Doped InP Nanowires.

We have grown InP nanowires doped with hydrogen sulfide, which exhibit sulfur concentrations of up to 1.4%. The highest doped nanowires show a pure wurtzite crystal structure, in contrast to bulk InP which has the zinc blende structure. The nanowires display photoluminescence which is strongly blue shifted compared with the band gap, well into the visible range. We find evidence of a second conduc

Small and large PROS1 deletions but no other types of rearrangements detected in patents with protein S deficiency

Protein S deficiency is a dominantly inherited disorder that results from mutations in the PROS] gene. Previous sequencing of the gene failed to detect mutations in eight out of 18 investigated Swedish families, whereas segregation analyses detected large deletions in three out of the eight families. The present study investigates more thoroughly for the presence of deletions but also for other ty

Analysis of the Auditory Perception of Ultrasound Doppler Signals to Improve Pregnancy Risk Assessment

In high-risk pregnancies, the transport of oxygen and nutrients from maternal to fetal blood via the placenta is often impaired. To assess the risk, pulsed Doppler ultrasound (US) is used to evaluate the flow velocity waveform in the umbilical artery with the pulsatility index (PI), which is derived from the velocity envelope of the Doppler power spectrum. However, simply listening to the Doppler

Use of healthcare resources after gestational diabetes mellitus: A longitudinal case-control analysis.

AIMS: To analyse whether gestational diabetes mellitus (GDM) was associated with increases in healthcare utilisation after delivery. METHODS: A longitudinal case-control registry-based study of 579 women with GDM delivered in 1995-2001. Two controls for each case were selected from the Swedish National Board of Health and Welfare, matched for year of birth, year of delivery, and municipality of r

1/f Noise Sources in Dual-Gated Indium Arsenide Nanowire Transistors

1/f noise is studied in dual-gated InAs nanowire transistors consisting of an omega top gate with high-k atomic layer deposited dielectric and silicon dioxide to substrate back gate. Noise spectra at varying gate bias combinations are compared from devices with differing top-gate lengths to separate the noise contributions of the top-gated channel from the ungated access portion, including the met

Leukocyte count and incidence of subarachnoid haemorrhage: a prospective cohort study.

Subarachnoid haemorrhage (SAH) is a devastating disease, in the majority of cases caused by a rupture of an arterial intracranial aneurysm. The effect of systemic low-grade inflammation on incidence of SAH is not known. The purpose of this study was to evaluate the relationship between leukocyte count, a marker of systemic inflammation, and incidence of SAH in a large cohort study.

Equity Market Risk Premium: Emerging and Frontier Markets

This research paper focuses on historical, arithmetic equity market risk premium in emerging and frontier markets. Equity market risk premium, as we know it today, has been easily estimated in developed markets; whereas, emerging and frontier markets often require different approaches to determine an appropriate equity market risk premium. I make use of a variety of methods, including volatility a

Population-wide incidence estimates for soft tissue knee injuries presenting to healthcare in southern Sweden: data from the Skane Healthcare Register

Introduction: Soft tissue knee injury is a well-established and potent risk factor for development of knee osteoarthritis. However, there is a paucity of epidemiological data from the general population. Our aim was to estimate the annual person-level incidence for a wide spectrum of clinically diagnosed soft tissue knee injuries, and their distribution by age, sex, and season. Methods: In Sweden,

Which Biomarkers Are Effective for Identifying Th2-Driven Inflammation in Asthma?

Recognition of asthma as a heterogeneous disease revealed different potential molecular targets and urged the development of targeted, customized treatment modalities. Evidence was provided for different inflammatory subsets of asthma and more recently, further refined to T helper (Th)2-high and Th2-low subphenotypes with different responsiveness to standard and targeted pharmacotherapy. Given the

Continuous gas-phase synthesis of nanowires with tunable properties.

Semiconductor nanowires are key building blocks for the next generation of light-emitting diodes, solar cells and batteries. To fabricate functional nanowire-based devices on an industrial scale requires an efficient methodology that enables the mass production of nanowires with perfect crystallinity, reproducible and controlled dimensions and material composition, and low cost. So far there have

Uniform and position-controlled InAs nanowires on 2('') Si substrates for transistor applications.

This study presents a novel approach for indirect integration of InAs nanowires on 2('') Si substrates. We have investigated and developed epitaxial growth of InAs nanowires on 2('') Si substrates via the introduction of a thin yet high-quality InAs epitaxial layer grown by metalorganic vapor phase epitaxy. We demonstrate well-aligned nanowire growth including precise position and diameter control

Low androstenedione/sex hormone binding globulin ratio increases fracture risk in postmenopausal women. The Women's Health in the Lund Area study.

The Women's Health in the Lund Area (WHILA) project (n=6917) is a cohort study that started in 1995 and includes a postal questionnaire, physical examination, bone density measurement and blood laboratory analyses. Fracture data have been added, and in this report fracture risk and its association with sex hormones was analysed in postmenopausal women without current hormone therapy (HT). A total