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Antimicrobial stewardship programs; a two-part narrative review of step-wise design and issues of controversy. Part II : Ten questions reflecting knowledge gaps and issues of controversy in the field of antimicrobial stewardship

Regardless of one’s opinion on antimicrobial stewardship programs (ASPs), it is hardly possible to work in hospital care and not be exposed to the term or its practical effects. Despite the term being relatively new, the number of publications in the field is vast, including several excellent reviews of general and specific aspects. Work in antimicrobial stewardship is complex, and include aspects

Assessment of search strategies in literature-review-based candidate theses within a nursing program

Background: The majority of candidate theses in baccalaureate nursing programs in Sweden are written as literature studies. Being able to carry out a systematic and structured literature search is an essential part of thesis-related work. Aim: The aim of the current study was to investigate changes in nursing students’ search strategies in candidate theses. Methods: A retrospective, quantitative s

Optical Force-Induced Dynamics of Assembling, Rearrangement, and Three-Dimensional Pistol-like Ejection of Microparticles at the Solution Surface

Optical trapping and assembling dynamics of polystyrene microparticles (MPs) of 1 μm in diameter are studied at its solution-air surface using a widefield microscope. Upon switching on the intense 1064 nm laser, the MPs are gathered, forming a single concentric circle (CC)-like assembly larger than the focus. It consists of a few tens of MPs, and the central part of the assembly shows structural c

Tail unsaturation tailors the thermodynamics and rheology of a self-assembled sugar-based surfactant

Hypothesis: The self-assembly of long-tail surfactants results in the formation of nanoscale structures, e.g. worm-like micelles, with the ability to modify the rheology of the system. However, micelle formation, and thus the alteration of the rheology, is subject to the high Krafft temperature of saturated long-tail surfactants. Hexadecylmaltosides are sustainable surfactants that, in solution, f

Bullying, health complaints, and self-rated health among school-aged children and adolescents

Objective: The aim of the current study was to examine whether health complaints and self-reported health were associated with bullying victimization in a large cohort of Icelandic children and adolescents. Methods: In this study, we used data from a school-based cross-sectional survey, specifically, the Icelandic contribution to the international research network Health Behavior in School-aged Ch

Tumor and nodal staging of colon cancer : accuracy of preoperative computed tomography at a Swedish high-volume center

Background: When deciding treatment options for patients with colon cancer, accurate staging is required. In Sweden, the main preoperative evaluation modality to determine tumor and nodal stage is computed tomography (CT).Purpose: The aim of this study was to investigate how well the preoperative (CT-determined) clinical tumor and nodal stage (cTN) correlated with the postoperative histopathologic

Advances in Thermal Imaging

Thermal imaging, or more correctly infrared thermography, has been widely applied to studies of animal and human biology (see Burnay et al. 1988; McCafferty 2007; Soerensen and Pedersen 2015; Fernandez-Cuevas et al., 2015; Tattersall 2016). This technique provides non-contact measurement of surface temperature, allowing real-time recording of the spatial temperature distribution of a body region,

Time Resolved Ambient Pressure X-ray Photoelectron Spectroscopy

This chapter describes basic principles and recent advances in time-resolved X-ray Photoelectron Spectroscopy with particular emphasis on studies conducted in complex reaction environments. Specifically, it discusses different ways for obtaining time information and achieving different time resolutions in tr-(AP)XPS experiment, covering timescales from fs to s. This includes experimental setups at

Daphnia magna trade-off safety from UV radiation for food

Research on diel vertical migration (DVM) is generally conducted at the population level, whereas few studies have focused on how individual animals behaviorally respond to threats when also having access to foraging opportunities. We utilized a 3D tracking platform to record the swimming behavior of Daphnia magna exposed to ultraviolet radiation (UVR) in the presence or absence of a food patch. W

Designing gate operations for single-ion quantum computing in rare-earth-ion-doped crystals

Quantum computers based on rare-earth-ion-doped crystals show promising properties in terms of scalability and connectivity if single ions can be used as qubits. Through simulations, we investigate gate operations on such qubits. We discuss how gate and system parameters affect gate errors, the required frequency bandwidth per qubit, and the risk for instantaneous spectral diffusion (ISD). Further

Accurate Prediction of Persistent Upper Extremity Impairment in Patients With Ischemic Stroke

Objective: To develop a simple and effective risk score for predicting which stroke patients will have persistent impairment of upper extremity motor function at 90 days. Design: Post hoc analysis of clinical trial patients hospitalized with acute ischemic stroke who were followed for 90 days to determine functional outcome. Setting: Patient were hospitalized at facilities across the United States

Fano resonance between Stokes and anti-Stokes Brillouin scattering

In recent years, the manipulation of Fano resonances in the time domain has unlocked deep insights into a broad spectrum of systems' coherent dynamics. Here, inelastic scattering of light with coherent acoustic phonons is harnessed to achieve complex Fano resonances. The sudden change of phonon momentum during reflection leads to a transition from anti-Stokes to Stokes light scattering, producing

A superconductor free of quasiparticles for seconds

Superconducting devices, based on the Cooper pairing of electrons, play an important role in existing and emergent technologies, ranging from radiation detectors1,2 to quantum computers3. Their performance is limited by spurious quasiparticle excitations formed from broken Cooper pairs4–12. Efforts to achieve ultra-low quasiparticle densities have reached time-averaged numbers of excitations on th

Probing strain in wurtzite InP-InAs core-shell nanowires with Raman spectroscopy

We used Raman spectroscopy to investigate phonon modes of single InP-InAs core-shell nanowire with a pure wurtzite phase to reveal the embedded strained state. Raman spectra show that the InP core exhibits tensile strain and the InAs shell exhibits compressive strain due to the radial heterostructure growth. Using different polarization excitation configurations, we identified distinct A1 (TO) and

Prevalence and severity of differing dimensions of breathlessness among elderly males in the population

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma

The social medicine specialty in southern Sweden

Aims: This article discusses the situation of the social medicine specialty in Skåne, southern Sweden with the aim of understanding the long-term trends of this medical specialty in Skåne and its relation to research in social medicine. Results: In the 1950s to 1980s, there was a balance between clinical and preventive practice, and research. This balance was maintained in the 1980s to early 2000s

Development of standard definitions and grading for Maternal and Fetal Adverse Event Terminology

Objective: Adverse event (AE) monitoring is central to assessing therapeutic safety. The lack of a comprehensive framework to define and grade maternal and fetal AEs in pregnancy trials severely limits understanding risks in pregnant women. We created AE terminology to improve safety monitoring for developing pregnancy drugs, devices and interventions. Method: Existing severity grading for pregnan

NanoMAX : The hard X-ray nanoprobe beamline at the MAX IV Laboratory

NanoMAX is the first hard X-ray nanoprobe beamline at the MAX IV laboratory. It utilizes the unique properties of the world's first operational multi-bend achromat storage ring to provide an intense and coherent focused beam for experiments with several methods. In this paper we present the beamline optics design in detail, show the performance figures, and give an overview of the surrounding infr