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Cyclodextrin Insulation Prevents Static Quenching of Conjugated Polymer Fluorescence at the Single Molecule Level.

Conjugated polymers (CPs) are promising materials for fluorescence imaging application. However, a significant problem in this field is the unexplained abnormally low fluorescence brightness (or number of fluorescence photons detected per one excitation photon) exhibited by most of CP single chains in solid polymer hosts. Here it is shown that this detrimental effect can be fully avoided for short

The 2008 financial crisis: Changes in social capital and its association with psychological wellbeing in the United Kingdom - A panel study.

The global financial crisis of 2008 was described by the IMF as the worst recession since the Great Depression. This historic event provided the backdrop to this United Kingdom (UK) longitudinal study of changes in associations between social capital and psychological wellbeing. Past longitudinal studies have reported that the presence of social capital may buffer against adverse mental health out

Materialist/postmaterialist values and their association with psychological health and health locus of control: A population-based study

This study investigates the association between Ronald Inglehart's materialist/postmaterialist index, a psychological aspect of the material pathway to inequalities in health, and health locus of control and psychological health. The data used is from the 2008 public health survey in Skane, a cross-sectional postal questionnaire study with 28,198 respondents (response rate 54%), conducted in south

Long term (13 years) prognosis after primary intracerebral haemorrhage: a prospective population based study of long term mortality, prognostic factors and causes of death.

INTRODUCTION: Many studies have focused on short term mortality after primary intracerebral haemorrhage (ICH) whereas long term prognosis and causes of death have been less studied. We therefore examined these issues in a population based cohort of 1 year ICH survivors. METHODS: ICH patients in a defined Swedish population (1.14 million inhabitants) were prospectively registered during 1996. Patie

Familial risks of breast and prostate cancers: Does the definition of the at risk period matter?

Aim: 'Being at familial risk' may have different connotations in studies on familial risk of cancer. The register-based definition of a family history considers individuals with an affected relative at familial risk independently of the family member's diagnostic time. Alternatively, the individuals are classified to be at familial risk only after the diagnosis date of their relative, relevant to

Nanoscale Confinement and Fluorescence Effects of Bacterial Light Harvesting Complex LH2 in Mesoporous Silicas

Many key chemical and biochemical reactions, particularly in living cells, take place in confined space at the mesoscopic scale. Toward understanding of physicochemical nature of biomacromolecules confined in nanoscale space, in this work we have elucidated fluorescence effects of a light harvesting complex LH2 in nanoscale chemical environments. Mesoporous silicas (SBA-15 family) with different s

Dermal uptake study with 4,4'-diphenylmethane diisocyanate led to active sensitization

BACKGROUND:To investigate the dermal uptake of 4,4'-diphenylmethane diisocyanate (4,4'-MDI), a study was performed in which 2 female volunteers were exposed to 10 and 25 mg, respectively, of 4,4'-MDI by applying 2.0% 4,4'-MDI in petrolatum over areas where the surface concentration corresponded to 800 µg/cm(2) . Ten days later, they developed eczematous dermatitis at the area of application.OBJECT

Is the physician's adherence to prescription guidelines associated with the patient's socioeconomic position? - An analysis of statin prescription in South Sweden.

BACKGROUND: Knowledge about the social and economical determinants of prescription is relevant in health care systems like the Swedish one, which is based on the principle of equity, and which aims to allocate resources on the basis of need and not on criteria that are based on social constructs. We therefore investigated the association between patient and health care practice (HCP) characteristi

Double-quantum two-dimensional electronic spectroscopy of a three-level system: Experiments and simulations

Double-quantum coherence two-dimensional (2Q2D) electronic spectroscopy is utilized to probe the dynamic fluctuations of electronic states in a solvated molecule at approximately twice the energy of the ground state bleach transition. The 2Q2D spectrum gives insight into the energetic position and spectral fluctuations (system-bath interaction) of the probed excited states. Combining it with singl

Misreporting and misclassification: implications for socioeconomic disparities in body-mass index and obesity.

Body-mass index (BMI) has become the standard proxy for obesity in social science research. This study deals with the potential problems related to, first, relying on self-reported weight and height to calculate BMI (misreporting), and, second, the concern that BMI is a deficient measure of body fat (misclassification). Using a regional Swedish sample, we analyze whether socioeconomic disparities

Defining the hematopoietic stem cell niche: the chicken and the egg conundrum

Understanding the in vivo regulation of hematopoietic stem cells (HSCs) will be critical to identifying key factors involved in the regulation of HSC self-renewal and differentiation. The niche (microenvironment) in which HSCs reside has recently regained attention accompanied by a dramatic increase in the understanding of the cellular constituents of the bone marrow HSC niche. The use of sophisti

Simultaneous Creation and Recovery of Trap States on Quantum Dots in a Photoirradiated CdSe-ZnO System

We study changes in the steady-state absorption and ultrafast transient absorption kinetics of the photoirradiated CdSe quantum dotZnO system. The changes enable us to reconstruct kinetics of trap creation, which are analyzed with respect to three possible models: trap creation without recovery, trap creation and recovery, and trap creation with an upper limit for trap number accommodated on a qua

A Six-Year Exercise Program Improves Skeletal Traits without Affecting Fracture Risk - a Prospective Controlled Study in 2621 Children.

Most pediatric exercise intervention studies, that evaluates the effect on skeletal traits include volunteers and follow bone mass for less than three years. We present a population-based six-year controlled exercise intervention study in children with also bone structure and incident fractures as endpoints. Fractures were registered in 417 girls and 500 boys in the intervention group (3969 person

Thermopower as a tool to investigate many-body effects in quantum systems

Measuring the thermopower of a confined quantum system reveals important information about its excitation spectrum. Our simulations show how this kind of transport spectroscopy is able to extract a clear signal for the onset of Wigner localization in a nanowire segment. This demonstrates that thermopower measurements provide a tool for investigating complex many-body quantum effects, which is less

Effect of metal oxide morphology on electron injection from CdSe quantum dots to ZnO

Performance of quantum dot sensitized solar cells relies on a rapid electron injection from quantum dot to metal oxide. We studied the injection process in CdSe-ZnO system by ultrafast time-resolved absorption spectroscopy for two types of acceptor morphologies-nanowires and nanoparticles' films. Based on comparison between experimental data and Marcus theory, we demonstrate that the acceptor morp

Insights into the Charge Carrier Terahertz Mobility in Polyfluorenes from Large-Scale Atomistic Simulations and Time-Resolved Terahertz Spectroscopy

Multiscale atomistic simulations were used to. understand the factors that determine the charge carrier mobility spectrum obtained from time-resolved terahertz (THz) spectroscopy in conjugated polymers. The simulation approach combines classical molecular dynamics simulations of atomic structure, large-scale electronic structure calculations, and the evaluation of the THz mobility using Kubo's lin

Swedish regional population-based organised prostate cancer testing : why, what and how?

Objective: This study aimed to describe the regional, population-based, organised prostate cancer testing (OPT) programmes that are being introduced throughout Sweden: motives, structure, target population, diagnostic algorithm, quality control, outcomes, research, and future perspectives. Results: In 2018, the Swedish National Board of Health and Welfare renewed their recommendation against scree