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Postnatal pesticide exposure and behavioural outcomes in children and adolescents : findings from South Africa

Introduction: Postnatal pesticide exposure and its association with child and adolescent behavioural outcomes remain underexplored in rural agricultural settings, particularly in Africa. This study examined behavioural outcomes in relation to urinary pesticide biomarkers and contextual exposure proxies in participants from the Child health Agricultural Pesticide (CapSA) cohort, South Africa. Metho

Exposure to perfluoroalkyl substances in early pregnancy and risk of sporadic first trimester miscarriage

Many first trimester sporadic miscarriages are unexplained and the role of environmental exposures is unknown. The present aim was to study if levels of Perfluoroalkyl substances (PFASs) in early pregnancy are associated with unexplained, sporadic first trimester miscarriage. The study was performed within the Swedish SELMA pregnancy cohort. Seventy-eight women with non-recurrent first trimester m

Promoting Prevention and Targeting Remission of Asthma : A EUFOREA Consensus Statement on Raising the Bar in Asthma Care

Asthma is a common, multifaceted respiratory disease with a major impact on quality of life. Despite increased insights into mechanisms underlying various asthma phenotypes and endotypes and the availability of targeted biologic treatment options, the disease remains uncontrolled in a substantial proportion of patients with risk of exacerbations, requiring systemic corticosteroids, and with progre

Association between neighborhood deprivation and type 2 diabetes risk among ADHD patients : a nationwide population-based cohort study

Objective: Both attention-deficit/hyperactivity disorder (ADHD) and neighborhood deprivation have been previously associated with an increased risk of type 2 diabetes (T2D). However, the potential association between neighborhood deprivation and T2D in ADHD patients remains underexplored. Our aim was to study the potential effect of neighborhood deprivation on incident T2D in patients with ADHD. M

Comparative safety and effectiveness of direct oral anticoagulants and warfarin in patients with venous thromboembolism in Finland, Norway and Sweden

Aim: Clinical trial data have demonstrated that direct oral anticoagulants (DOACs) are both noninferior to and safer than conventional therapy for the treatment of venous thromboembolism (VTE). This study aimed to compare the effectiveness and safety of DOACs versus warfarin using Nordic population-based registries. Materials & methods: This observational cohort study used Swedish, Norwegian a

The Nurses' Role in the Cardiac Rehabilitation Team : Data from the Perfect-CR Study

Background Nurses constitute a central profession in the cardiac rehabilitation (CR) team delivering comprehensive CR to individuals with cardiovascular disease. We aimed to identify specific components reflecting the nurses' role in the CR team associated with attainment of risk factor targets post myocardial infarction. Methods Center-level data (n = 78) was used from the Perfect-CR study, in wh

Upper-Limb Complications in Diabetes : A Narrative Review

Upper-limb complications (ULCs) in diabetes, affecting joints, tendons, muscles, con-nective tissue, nerves, and skin, are underrecognized but prevalent conditions in type 1 and type 2 diabetes. Advances in diabetes care have extended life expectancy, leading to an aging population with diabetes with increased susceptibility to long-term complications beyond traditional vascular issues. Despite so

The Utility of Maternal Blood S100B in Women with Suspected or Established Preeclampsia—A Systematic Review

Purpose: Preeclampsia is a serious pregnancy complication without curative treatment. The central nervous system (CNS) is affected in severe cases of preeclampsia. Until now, no biomarker or other predictive method has been established for predicting severe CNS injury, including the development of eclampsia and/or long-term complications. In this systematic review, we aimed to investigate the asso

Determinants of urinary pesticide metabolite concentrations in school-aged children from rural Bogotá, Colombia

This study aimed to determine urine pesticide metabolite concentrations using liquid chromatography and investigate associated exposure factors in a rural area of Bogotá, Colombia. In 2019, 231 urine samples were collected from children aged 7 to 10. Urinary pesticide metabolite concentrations were measured, and a questionnaire was administered to the children’s mothers to collect exposure-related

Smog Chamber Experiments of SOA Formation from Gasoline Exhaust and Light Aromatics

Experiments where gasoline exhaust was exposed to UV-radiation to examine Secondary Organic Aerosol (SOA) formation were performed in a smog chamber. The Aerosol Mass Yield (formed SOA/reacted precursor mass) was determined and compared with the yield from a pure precursor experiment in the chamber and from results reported in literature. Preliminary results show that the majority of the organic a

Growth of Semiconductor Nanowires for Solar Cell Applications

Nanowires have the ability to absorb light much more efficient than conventional thin film layers. This makes them candidates for the development of new types of solar cells that have higher efficiency and lower material usage than current technologies. In this thesis fabrication of nanowires with techniques suitable for large area applications are investigated. The nanowires are grown by either M

Charge Transport in Semiconductor Nanowire Quantum Devices: From Single Quantum Dots to Topological Superconductors

This thesis focuses on charge transport in semiconductor InSb nanowire quantum devices, including the electron transport, the hole transport, and the Cooper pair transport. Devices in which InSb semiconductor nanowire quantum dots are coupled with normal metals, superconductors or the proximity effect induced topological superconductors are fabricated and measured. Firstly, we have fabricated and

Interface composition of atomic layer deposited HfO2 and Al2O3 thin films on InAs studied by X-ray photoemission spectroscopy

We present a synchrotron-based XPS investigation on the interface between InAs and Al2O3 or HfO2 layers, deposited by ALD at different temperatures, for InAs substrates with different surface orientations as well as for InAs nanowires. We reveal the composition of the native Oxide and how the high-k layer deposition reduces Oxide components. We demonstrate some of the advantages in using synchrotr

Theory of Random Matrices and Elasticity Applied to Nanowires and Mechanical Vibrations

This thesis presents work in several areas relating to Random Matrix Theory and Elasticity. It contains 4 papers presenting work on different issues. Paper I concerns correlations between eigenvalues in random matrices of real symmetric (GOE) or quaternion real (GSE) form. It presents a calculation showing that correlations between arbitrarily many eigenvalues can be obtained from averages of a t

Development of Second and Third Generation Bioelectronics

The field of research dealing with the integration of biomolecules with electronic elements to form functional devices is called ‘‘bioelectronics’’. Bioelectronics based on mediated electron transfer (MET) between the biological element and the electrodes are designated as “second generation” while the one based on direct electron transfer (DET) is specified as “third generation”. Implanted bioele