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ERP systems became popular with large organizations in the 1990s. In the 21st Century, these products were expanded by addition of supply chain management (SCM) and customer relationship management (CRM), as well as access through the Web, creating the ERP II concept. Efforts to increase the market led vendors to serve not only large organizations, but also focus more on small-to-medium sized ente
This thesis describes our efforts towards the total synthesis of natural products and the development of a newmethodology to afford a synthetically important scaffold.Chapter 2 outlines our efforts towards the total synthesis of a marine natural product, perophoramidine as wellas our completed synthesis of dehaloperophoramidine. The focus of the studies was to develop an efficient andconcise strat
Linear multistep methods (LMMs) constitute a class of time-stepping methods for the solution of initial value ODEs; the most well-known methods of this class are the Adams methods (AMs) and the backward differentiation formulae (BDFs). For the fixed stepsize LMMs there exists an extensive error and stability analysis; in practical computations, however, one always uses a variable stepsize. It is w
Popular Abstract in Swedish Modelleringsarbetet utvecklat i denna avhandling, kan delas in i två huvudområden: självantändning i ottomotorer, samt förbränning och emissioner i dieselmotorer. En första version av ett motorsimuleringsprogram med detaljerad kemisk kinetik, utökad för att innefatta full-cykel beräkningar, användes för att visa den starka påverkan som kväveoxider i restgaser har på sjThe modeling work developed in this thesis can be divided in two main areas of investigations: autoignition related to spark ignition engine and combustion and emissions formation in relation to diesel engines. A first version of a detailed kinetics engine simulation program, extended to handle full cycle calculations, was employed in order to demonstrate the strong effect that nitric oxide from
Inactivation of the Ink4 gene locus locus on 9p comprising the tumour suppressor gene p16ink4a and its neighbours p14ARF and p15ink4b is common in childhood acute lymphoblastic leukaemia (ALL), but the prognostic significance is controversial. DNA from 230 patients was retrospectively analysed by Southern blotting, single strand conformation polymorphism (SSCP) and sequencing techniques. The resul
The physiological characteristics of native and bacterial exopolysaccharides (EPS) in oats and barley-based fermented products were studied in relation to the physico-chemical properties. Article I presents a parallel-randomized double blind clinical trial using a dairy-based product (control), an oat-based product (fermented with V2, which is a mixture (1:1) of Lactobacillus delbrueckii subsp. Bu
Popular Abstract in Swedish Diabetes är en folksjukdom där c:a 350000 människor i Sverige är drabbade. Fotsår är en vanlig komplikation vid diabetes, och sådana svårläkta sår leder till c:a 700 diabetesrelaterade amputationer årligen. Såväl såren som amputationssituationen orsakar funktionshinder, smärta, sociala bekymmer samt psykisk stress för dem som drabbas. Att utveckla nya och förbättrade beDiabetes wounds result in significant morbidity, prolonged hospitalization and huge health care expenses. As of yet, no optimal animal models of diabetic wound healing exist to study potential beneficial therapies. Porcine wound healing is very similar to human wound healing. We stipulated that by inducing diabetes in yorkshire pigs, wound healing would be delayed and exhibit abnormalities similar
Objective: To assess the prevalence and risk factors of emergency peripartum hysterectomy. Design:Nordic collaborative study. Population605362 deliveries across the five Nordic countries. Methods: We collected data prospectively from patients undergoing emergency peripartum hysterectomy within 7days of delivery from medical birth registers and hospital discharge registers. Control populations cons
Klimatet har varit relativt stabilt under den nuvarande interglaciala epoken (Holocen) som inleddes för ungefär 11 700 år sedan. Genom klimatrekonstruktioner från olika geologiska arkiv såsom iskärnor, sjösediment och torvmossar har det ändå påvisats att snabba förändringar i klimatet har inträffat under denna epok. En sådan tidsperiod inträffade för omkring 2800 år sedan och den är intressant ur Geological archives have shown periods of abrupt climate change in the relatively stable Holocene epoch (last ca. 11 700 years). One of these periods was around 2800 cal BP. Several records, mainly from Europe, reveal a shift towards wetter, cooler and windier conditions. There are, however, indications for a global extent of the climate change. The climate change coincides with a distinct increas
Här behandlas Sveriges förbindelser med andra politisk-territoriella enheter, frånmedeltidens dynastiska unioner över de tidigmoderna konglomeratstaterna till1800-talets union av två nationalstater. Med hjälp av befintlig forskning fokuserasstatens växlande sammansättning och vikten av att skilja mellan riket och staten.Ett sådant perspektiv visar nya aspekter och ställer frågor som ett traditioneDuring most of the period from 1319 to 1905, the kingdom of Sweden formed part of a larger state, either through union with other states or through the possession of provinces that were not part of the kingdom proper. This is a neglected theme in Swedish historiography, where Sweden is described as a trans-historical entity, sometimes larger and sometimes smaller than the present state but still b
Although l-3,4-dihydroxyphenylalanine (l-DOPA) remains the reference treatment of Parkinson's disease, its long-term beneficial effects are hindered by l-DOPA-induced dyskinesia (LID). In the dopamine (DA)-denervated striatum, l-DOPA activates DA D1 receptor (D1R) signaling, including cAMP-dependent protein kinase A (PKA) and extracellular signal-regulated kinase (ERK), two responses associated wi
This dissertation consists of three empirical essays concerning social norms and their effect on economic outcomes. Each essays discusses a seperate subject. The first paper, Breaking the Glass Ceiling: Gender Norms and Women Executives in the United States studies social norms as a distal cause of differences between genders in corporate executive recruitment strategies. Using census-level panel This dissertation consists of three empirical essays concerning social norms and their effect on economic outcomes. Each essays discusses a seperate subject. The first paper, Breaking the Glass Ceiling: Gender Norms and Women Executives in the United States studies social norms as a distal cause of differences between genders in corporate executive recruitment strategies. Using census-level panel
By "codex simulations" or codex simulaters" I intend the various hard- and software products that imitate the form of the codex and /or simulate the function of it. They can be designed with the main purpose either to transfer literary work, as with "ordinary" electronic books, or to communicate the looks of a specific original artefact, as with those simulaters used by libraries for displaying di
Medlingsinstitutet är en alternativ konflikthantering där parterna ges möjlighet att påverka konfliktens lösning och att återställa lugnet parterna emellan. Transaktioner är inte alltid friktionsfria och situationer kan uppstå där en av parterna vill föra saken inför domstol. Det är inte ovanligt att ombud i dessa situationer hotar om stämning som en skrämseltaktik för att ge sin part en hävstång.The Mediation Institute is a form of dispute resolution alternative to the judicial process where the parties may impact with the process and can influence the outcome, all in the purpose of restoring the calm between the parties. Transactions are not always successful and may result in a dispute where one party is inclined to take the dispute to court. It is not unusual that a part’s lawyer uses
Den tekniska utvecklingen innebär att det finns nya sätt att kränka en annan person som inte överensstämmer med de tillvägagångssätt som tidigare avsetts i svensk straffrätt. Förevarande uppsats är en undersökning av straffbara ofredanden på sociala medier. Utredningen görs med utgångspunkt i den kritik som riktats mot svensk lagstiftning. Två bestämmelser som kan aktualiseras när brott begås via Due to the technical development, new ways of violating another person has been created. These ways do not comply with the procedures previously set out in Swedish penal law. This essay is an investigation of criminal offenses carried out on social media. The research is based on the criticism raised towards Swedish legislation. Focus lies on two provisions, molestation and sexual molestation acco
Acute myeloid leukemia (AML) is one of the most common and deadliest form of blood cancer in adults, accounting for over 80% of acute leukemic diagnoses. Despite the introduction of new targeted therapies, survival rate remains low in adults, and new therapeutic approaches are needed. In a previous CRISPR screen performed by the Järås group, CALRETICULIN was identified as a regulator of human leuc
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https://www.staff.lu.se/sites/staff.lu.se/files/modellavtal_forfattare_forlag.pdf - 2026-07-20
Background/introduction: E-commerce is becoming a natural part of retail business. In order to achieve a competitive edge, companies are shifting to omni channel retailing where channel integration is explored in the search for potential improvements in connection with customer offer and costs. One solution is to integrate inventories and offer improved order fulfilment by using both warehouse and
