Filtyp
Platform trials have become widely adopted across multiple disease areas over recent years, however, guidelines for operationalising these trials have not kept pace. We outline a series of documents that summarise the statistical components, and implicit processes, of the Staphylococcus aureus Network Adaptive Platform (SNAP) trial to provide an informal template for other researchers and reviewer
ObjectiveSputum cultures can guide antibiotic therapy, particularly in severe pneumonia or when resistant pathogens are suspected. However, data on how prior and ongoing antibiotic exposure affects microbial detection are limited. This study aimed to evaluate this impact, stratified by timing and route of administration.MethodsIn- and outpatients from nine hospitals in Skåne, Sweden, who submitted
A search is conducted for a new scalar boson S, with a mass distinct from that of the Higgs boson, decaying promptly into four leptons (ℓ=e, μ) via an intermediate state containing two on-shell, promptly decaying new spin-1 bosons Zd: S→ZdZd→4ℓ, where the Zd boson has a mass between 15 and 300 GeV, and the S boson has a mass between either 30 and 115 GeV or 130 and 800 GeV. The search uses proton–
A search for the production of top-quark pairs with the same electric charge (tt or tt¯) is presented. The analysis uses proton-proton collision data at s = 13 TeV, recorded by the ATLAS detector at the Large Hadron Collider, corresponding to an integrated luminosity of 140 fb−1. Events with two same-charge leptons and at least two b-tagged jets are selected. Neural networks are employed to define
Democracies face a crisis of public reason grounded in a disintegration of shared epistemic ground and amplified by digital polarisation and AI-mediated disinformation. Current pedagogy, focused on deconstructive critique or fact-checking skills, fails to address how algorithmic systems engineer plausibility at scale. Higher education must cultivate discerning judgement alongside critique. Drawing
The term self-determination is embedded in much difficulty. It is a term whose meaning has developed considerably from its first intended usage. Today, in a world that is in several respects becoming smaller and more conformed, certain peoples claim rights they have previously not been granted in order to protect their subsistence and preserve their culture. The Sami is one of these peoples. This
Water resources management has been reconfigured over time and space; as power over decision-making processes has increasingly been vested from the state and distributed among networks of private and non-governmental actors. Geographical scholarships of environmental governance seek to critically analyse this transformation in order to grasp how decisions are made, and the consequences that entail
The question of secondary liability of internet intermediaries for illegal content online is closely linked to the enjoyment of freedom of expression that has to be guaranteed both online and offline. The provisions concerning internet service providers’ liability in Europe include ‘notice and take down’ procedure, blocking measures and injunctions against intermediaries, which are all well-desi
The actions of states are governed by norms. These norms regulate what is looked upon as desirable behaviour and what is not. In recent years the norm about women, peace and security has developed and resulted in the UN Security Coun-cil Resolution 1325. The aim of the resolution is to make peace processes more inclusive and take issues related to women into concern. Despite the resolution much is
Variability of atmospheric circulation is considered one of the most important factors causing interannual and interdecadal variability of freshwater amount that is discharged from the continents. Here it is presented an analysis of the relations between the discharge variability of five major rivers in the Mediterranean basin (i.e. Adige, Arno Ebro, Po and Rhone) responsible for the 70% of total
Striving to contribute to research on child- and youth spirituality and African theology with a contextually grounded, non-western, qualitative youth perspective, the aim of this study is to seek an understanding of the spirituality of male youth that live on the streets in Nairobi. To fulfil this aim, the research task carried out is an analysis of the source material from six focus group intervi
The master thesis seeks to develop a control system for the Crazyflie 2.0 unmanned aerial vehicle to enable aggressive and autonomous flight. For this purpose, different rigid-body models are considered, differing primarily in their parametrisation of rotation. The property of differential flatness is explored and several means of parametrising trajectories in at output space are implemented. A ne
In order to enable an effective and efficient adoption of radical innovations in networks, science-based organizations should be aware of the challenges and resistance they may face within their network relationships, resulting from the interconnected structure of high-tech networks as well as the uncertain nature of their radical innovations. By analyzing how nuances of relationship quality influ
Water management tackles complexities within the interconnected social, political, economic and ecological systems across scales, while aiming to meet the needs of multiple stakeholders dependent on water. Many tensions and unsolved issues persist in water management regarding socio-political power structures, spatial scale, and relations between stakeholders who have different perceptions on prob
Insects have been recommended by the FAO as a sustainable food alternative to meat. Despite their nutritional quality and sustainability, most Western countries still see insects as belonging far away from the dinner table. Although still a niche market, Denmark has been at the forefront of innovation and adoption of edible insects. I used integral theory to map out the structural, cultural and pe
Development of valuable products from downstream process residual biomasses and profound reduction of waste are two key components for developing a more sustainable process industry. The importance of bio-renewable feedstocks and bio-based processing techniques are also crucial in the transformation to a more sustainable and green society. Therefore focus is directed on full exploitation of seawee
Central to the field of agrarian political economy, is rural development and capitalism’s advancement in the countryside and its consequences for the peasantry, ‘the agrarian question’. With the present case study, I examine the interplay between social relations of production and agrarian change in eastern Bolivia. Using the case study of Ramada, a small indigenous community, this dissertation in
The occurrence of climate change will have a significant impact on society and adapting to a more sustainable environment is of key importance. The dangers of climate change will include temperature and precipitation patterns becoming more extreme creating a substantial impact on society. Greece’s location and climate make it particularly vulnerable to a changing climate and climate impact assessm
Mountains provide a variety of ecosystem services, such as drinking water, which sustains not only mountain communities but also people living further downstream. While climate change threatens most ecosystems, its negative impacts are up to three times greater in high altitudes. As well as changing the water cycle this further accelerates climate change. Although they contribute comparably little
