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Identification of the target for therapeutic recombinant anti-apoB-100 peptide antibodies in human atherosclerotic lesions.

PURPOSE: Accumulation of oxidized LDL in the arterial wall is believed to play a key role in the development of atherosclerosis. Experimental studies have identified the presence of immune responses against epitopes in oxidized LDL that protects against atherosclerosis. We have produced human recombinant IgG against one of these epitopes (aldehyde-modified apoB-100 amino acids 661-680) and demonst

Berättelser om stroke och arbetsliv : Att upptäcka styranderelationer

The starting point in this thesis is stroke inflicted individuals’ stories about their experience of stroke, relations in everyday life, and their relations and attempts to return to paid work with the objective of gaining a further understanding of what happens when inflicted by illness and/or disability in working age. Furthermore, it aims at understanding how social relations and ruling relatio

Sustainable vehicle fuels - do they exist?

Our aim with this report is to discuss vehicle fuels from a wide perspective of sustainability. Biofuels and electricity are analyzed and compared to fossil vehicle fuels. Our goal is to try to point out the circumstances under which vehicle fuels can be reasonably perceived as sustainable, and which systems we should develop and which we should avoid. The all-embracing conclusion of this study is

Screening Detects a High Proportion of Celiac Disease in Young HLA-genotyped Children.

BACKGROUND AND AIMS:: Celiac disease is associated with tissue transglutaminase autoantibodies (tTGAb) and the human leukocyte antigen (HLA)-risk alleles DQB1*02 and DQB1*0302. The aim was to estimate the proportion of undiagnosed celiac disease in children with HLA risk at 3 years of age. PATIENTS AND METHODS:: From a population-based HLA-DQ screening study of newborns born between June 2001 and

Förändring av deltagandet i produktionen : Exempel från slutmonteringsfabriker i Volvo

This dissertation focuses on the changes in the organization of the production process that occurred at Volvo Cars and Volvo Trucks in the early 1990s. The changes were directed at the established division of labor – both vertical and horizontal – between different groups of employees: managers, foremen, white and blue-collar workers. The questions posed are primarily concerned with the changes fo

Survival in cancer patients hospitalized for psoriasis: a population-based cohort study in Sweden.

Background Increased cancer risk after psoriasis has been observed in previous studies, whereas little is known about the prognosis in cancer patients with previously diagnosed psoriasis. Objectives We aimed at examining the cancer-specific and overall mortality among psoriatic cancer patients compared with the reference population. Methods The population-based Swedish registers were used to ident

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes : Results from a randomized clinical trial

Aims Metformin therapy is associated with diffuse intestinal 18F-fluoro-deoxyglucose (FDG) accumulation in clinical diagnostics using routine FDG-PET imaging. We aimed to study whether metformin induced glucose uptake in intestine is associated with the improved glycaemic control in patients with type 2 diabetes. Therefore, we compared the effects of metformin and rosiglitazone on intestinal gluco

Impact of penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm for 18 F-fluorocholine PET-CT regarding image quality and interpretation

Background: Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-penalizing factor (β), acquisition time, and administered activity for optimal image quality has not been established for 18 F-fluorocholine (FCH). The aim was to compare image

”The queer disappearance of Butler" : När Judith Butler introducerades i svensk feministisk forskning, 1990-2002

This article on the Swedish reception of the work and theories of feminist philosopher Judith Butler follows four feminist fields that introduced and discussed Butler’s work from the early 1990’s to the early 2000’s; the first and earliest being the radical feminist field, followed by the field of feminist literary studies, the field of queer theory and, as a field of its own, the various translat

Lost in Translation: Queer Studies in Sweden

The word queer landed in Sweden in a terminological and theoretical vacuum. It was not that nobody had studied issues and theories relating to sexualities and identities before queer theory were introduced, but the approach of the then new queer theory was slightly different. Above all, it concerned a term that had no history in the Swedish language. Queer is not a Swedish word, and therefore it c

Drug costs and benefits of medical treatments in high-unmet need solid tumours in the Nordic countries

Introduction: Regional and hospital decision-makers increasingly require analyses assessing the cost-benefit profile of new cancer drugs. This analysis evaluates the cost-benefit profile of nano albumin-bound paclitaxel (nab-paclitaxel) in pancreatic cancer, versus other drugs indicated in high-unmet need solid tumour indications in Nordic countries (Sweden, Denmark, Finland, Norway and Sweden). M

Ultrafast photoisomerization of pinacyanol : Watching an excited state reaction transiting from barrier to barrierless forms

Photoisomerization of 1,1′-diethyl-2,2′-carbocyanine iodide (pinacyanol) in alcohols was investigated by means of femtosecond time-resolved absorption spectroscopy. Only one out of two possible types of photoisomer was found. Viscosity-dependent kinetics indicate that the excited state dynamics consist of two parts, associated with a barrier-crossing observed in the blue side of stimulated emissio

Ny forskning vill identifiera personer som riskerar kronisk psykos – Vetenskap och Hälsa

Ny forskning vill identifiera personer som riskerar kronisk psykos – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ny forskning vill identifiera personer som riskerar kronisk psykos 2010-05-26 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Psykos är en av v

https://www.vetenskaphalsa.se/ny-forskning-vill-identifiera-personer-som-riskerar-kronisk-psykos/ - 2026-06-02

Administration of monoclonal antibodies neutralizing the inflammatory mediators tumor necrosis factor alpha and interleukin -6 does not attenuate acute behavioral deficits following experimental traumatic brain injury in the rat

PURPOSE: Although many previous studies have indicated that the acute inflammatory response following traumatic brain injury (TBI) is detrimental, inflammation may also positively influence outcome in the more chronic post-injury recovery period. We evaluated the effects of monoclonal antibodies (mAB), neutralizing either IL-6 (IL-6 mAB) or TNF-alpha (TNF mAB), administered intracerebroventricular

Fermented, ropy, oat-based products reduce cholesterol levels and stimulate the bifidobacteria flora in humans

This investigation determined the effects of fermented oat-based products containing both native and microbial beta-glucans on plasma lipids and on fecal total bacterial count and Bifidobacterium ssp. The study was randomized, double blind with 3 parallel groups. Sixty-two free-living volunteers with moderately increased plasma cholesterol levels were recruited. In the final analysis, 56 subjects

Survival in prospectively ascertained familial breast cancer: Analysis of a series stratified by tumour characteristics, BRCA mutations and oophorectomy

Dedicated clinics have been established for the early diagnosis and treatment of women at risk for inherited breast cancer, but the effects of such interventions are currently unproven. This second report on prospectively diagnosed inherited breast cancer from the European collaborating centres supports the previous conclusions and adds information on genetic heterogeneity and the effect of oophor

På jakt efter språk : om språkdelen i gymnasieskolans svenskämne

Popular Abstract in Swedish Ett gemensamt drag i befintlig forskning är att språkliga delar av gymnasieskolans svenskämne framstår som diffusa och tycks sakna kärna och teoretisk ram. Syftet med avhandlingen På jakt efter språk är att beskriva och problematisera språkdelen i gymnasieskolans svenskämne. Undersökningen är gjord i två klasser på studieförberedande program under deras första termin i A common feature of existing research is that the linguistic part of the subject Swedish in upper secondary school appears to be diffuse and seems to lack core and theoretical framework. The purpose of the thesis ’Hunting for language’ is to describe and investigate how the linguistic part of Swedish is handled in upper secondary school. The study was carried out in two classes of college-preparat

Inflammation-sensitive proteins and risk of atrial fibrillation: a population-based cohort study.

Low-grade inflammation has been repeatedly associated with cardiovascular diseases but the relationship with incidence of atrial fibrillation (AF) remains unclear. We explored the association between elevated plasma levels of inflammation-sensitive proteins (ISPs) and incidence of AF in a population-based cohort. Plasma levels of five ISPs (fibrinogen, haptoglobin, ceruloplasmin, α(1)-antitrypsin

Self-injury in youths who lost a parent to cancer: nationwide study of the impact of family-related and health-care-related factors

Background: Self-injury, a manifestation of severe psychological distress, is increased in cancer-bereaved youths. Little is known about the potential influence on the risk for self-injury of factors that could be clinically relevant to and modifiable by the health-care professionals involved in the care of the dying parent. Methods: In a nationwide population-based anonymous study, 622 (73.1%) yo

Cancer incidence among Iranian immigrants in Sweden and Iranian residents compared to the native Swedish population

Background and goals: Comparing cancer incidence by migrant studies is one of the main approaches to generate hypotheses on the aetiology of cancer. Immigrant studies are most informative when cancer incidence data are available from both the Source and the host country. Methods: The age standardised incidence rate (ASR) and standardised incidence ratio (SIR) of cancers among the Iranian immigrant