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Effective treatment of haemophilic arthropathy requires a detailed evaluation of joint integrity. Methodological assessment of magnetic resonance imaging (MRI) scores are needed to assure reproducibility of measurements when comparing results of clinical trials conducted in different centres. We compared the reliability of two MRI scoring systems for assessment of haemophilic arthropathy: one prog

In Sweden, clear changes in the care of the elderly have occurred during the 1990s, with fewer people being provided public care, although greater efforts are now directed towards those most in need of help. Elderly people are cared for increasingly in other ways: by the family, by means of market-provided care, and by voluntary and informal means. Differences between municipalities are considerab

The angular pattern of scattered synchrotron x-ray radiation has been used to measure the composition of molecules and nanometer-sized particles in flames. The measured patterns were compared with patterns obtained from calculations for different species compositions. After ensuring that the calculations could reproduce the experiments for air and for ethylene flames under two different combustion

We investigate the competition between the associations of oppositely charged protein-surfactant complexes and oppositely charged surfactant complexes. In all systems examined, the most favorable complexation is the one between the two oppositely charged surfactant ions, despite the strong binding known, for example, dodecyl sulfate, DS-, to lysozyme. Thus, the phase behavior of the catanionic sys

Many bactericide species express surface proteins that interact with human serum albumin (HSA). Protein PAB from the anaerobic bacterium Finegoldia magna ( formerly Peptostreptococcus magnus) represents one of these proteins. Protein PAB contains a domain of 53 amino acid residues known as the GA module. GA homologs are also found in protein G of group C and G streptococci. Here we report the crys

PURPOSEAPR-246 (PRIMA-1MET) is a novel drug that restores transcriptional activity of unfolded wild-type or mutant p53. The main aims of this first-in-human trial were to determine maximum-tolerated dose (MTD), safety, dose-limiting toxicities (DLTs), and pharmacokinetics (PK) of APR-246. PATIENTS AND METHODSAPR-246 was administered as a 2-hour intravenous infusion once per day for 4 consecutive d

The aim of this study is to investigate if self-reported activity level or knee functions are influenced by subject characteristics, level of competition and history of knee injury. Cross-Sectional study using questionnaires distributed at a personal visit. One hundred and eighty-eight (65 women) amateur football players in 10 football clubs from each division below national level participated in

Purpose To assess the natural history of intrameniscal signal intensity on magnetic resonance (MR) images of the medial compartment. Materials and Methods Both knees of 269 participants (55% women, aged 45-55 years) in the Osteoarthritis Initiative without radiographic knee osteoarthritis (OA) and without medial meniscal tear at baseline were studied. One radiologist assessed 3-T MR images from ba

Abstract in UndeterminedBackgroundScreening for colorectal cancer (CRC) has been shown to decrease mortality.ObjectiveTo examine determinants associated with having (1) a screening colonoscopy, (2) an appropriate indication for screening, and (3) a significant diagnosis at screening.DesignProspective observational study.SettingTwenty-one endoscopy centers from 11 countries.PatientsAsymptomatic pat

Semiconductors are the backbone of almost every electrical or optical component, one of them being photodetectors. Photodetectors are used in many applications such as digital cameras or solar panels. They can also be designed to detect the omnipresent infrared radiation, discovered in 1800, which is invisible to human eye. Such infrared photodetectors are commercially used in e.g. night-vision, o

The docking protein p140Cap negatively regulates tumour cell features. Its relevance on breast cancer patient survival, as well as its ability to counteract relevant cancer signalling pathways, are not fully understood. Here we report that in patients with ERBB2-amplified breast cancer, a p140Cap-positive status associates with a significantly lower probability of developing a distant event, and a

I Sverige förekommer fortfarande problem med hedersrelaterade våldsbrott. År 2016 var en tredjedel av alla mord som begicks mot kvinnor hedersrelaterade. Många röster har höjts för att en straffskärpning bör ske på området. Mitt syfte med uppsatsen har varit att utreda om det finns ett behov att införa en särreglering vad gäller våldsbrott med heder som motiv i straffskärpande syfte. Följande frågIn Sweden there are still problems with honor-related violent crime. In 2016, one third of all murders committed against women were honor-related murders. Many voices have been raised in order for a punishment to take place in the area. The purpose of the present paper has been to investigate whether there is a need to introduce a special regime for violent crime with honor as a motive for puniti

Musical meaning is multifaceted: both highly sensory and yet often abstract, able to cross cultural boundaries and yet embedded in specific traditions. For the most part it is not denotational (Monelle, 1991). Nevertheless, in “programmatic music”, musical themes are intended to refer to worldly objects and events on the basis of iconic (and indexical) grounds. Such non-arbitrariness of the sound-

IPC-kontroller (In-process Controls) är kontroller som utförs i produktion för att säkerhetsställa kvalitet. På TePe Munhygienprodukter AB (TePe) fanns ett stort behov av att utvärdera, analysera och optimera IPC-kontroller i deras produktion vilket motiverade detta examensarbete. TePe hade omfattande problem gällande kassation av stora mängder defekta produkter samt avsaknad av tydliga instruktioIn-process Controls (IPC) are controls performed to ensure quality in production. At TePe Munhygienprodukter AB (TePe) there was a need to evaluate, analyze and optimize the IPC:s in their production which was the motivation for this master thesis. TePe had extensive problems regarding the disposal of large amounts of defect products and the absence of clear instructions describing the execution o

Financial markets turn all their attention towards the Federal Reserve Bank and the European Central Bank whenever there are the slightest rumors of a change in the policy rate of interest. But why is this rate so important and what is the theoretical basis of its existence in the first place? In modern economic literature theories of interest are rarely explicitly touched upon and interest is oft

Greenlanders in Denmark are often overlooked in the spheres of the Danish society. One stereotypical image of the Greenlander has become ingrained to be almost commonsensical in its use in the Danish language and media. That is the Greenlander as the loser in Danish society, someone who is either drunk, homeless, or destitute. Although some Greenlanders suffer from these issues, the majority of th

Title: Using scenarios to balance future requirements and capability development Author: Erik Jacobsson Division: Production Management Supervisors: Bertil Nilsson at the Technical Faculty of Lund University, Innovation Advisor at the case company Keywords: Scenarios, Corporate development, Energy Sector, Capabilities, Technology Background: The speed of change in the world is ever increasing

I år, 2020 har ett lagförslag från Boverket angående krav på klimatdeklarationer lämnats på remiss. Lagförslaget handlar om att fastställa ett krav på byggherrar, att vid nybyggnationer inkludera en klimatdeklaration. Denna klimatdeklaration ska verkställas genom att utföra en livscykelanalys på hela nybyggnationens klimatskal, stomme och innerväggar. För att kunna förenkla arbetet med klimatkalkyThis year, 2020, a bill from the Swedish National Board of Housing, Building and Planning regarding requirements for climate declarations has been submitted on a referral. The bill is about establishing a requirement for builders, to include a climate declaration for new buildings. This climate declaration is to be implemented by performing a life-cycle analysis of the entire new building's cl

Beskattningstidpunkten för lön i inkomstslaget tjänst styrs som huvudregel av kontantprincipen. Lönen ska tas upp det beskattningsår då arbetstagaren kan disponera över den eller då den på något annat sätt kommer arbetstagaren till del. Som arbetstagare kan man få erbjudande av sin arbetsgivare om att växla viss del av sin kontanta lön mot en förmån alternativt skjuta upp viss del av sin kontantAs a rule, the time of taxation for salary is governed by a principle that states that the salary is taxed the taxable year when the employee can dispose it or when it in an other way benefits the employee. As an employee, one can receive an offer from the employer to exchange a certain portion of the salary to a benefit or to postpone a certain portion of the salary to a future payment, so-calle