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Background: Ten to 30% of HIV-1 infected subjects develop broadly neutralizing antibodies (bNAbs) during chronic infection. We hypothesized that immunizing rabbits with viral envelope glycoproteins (Envs) from these patients may induce bNAbs, when formulated as a trimeric protein and in the presence of an adjuvant. Methods: Based on in vitro neutralizing activity in serum, patients with bNAbs were
Delivery of fetuses with intrauterine growth restriction (IUGR) with abnormal umbilical artery blood flow in the second trimester represents a clinical dilemma. So far, no evidence based management protocols are available adressing when to deliver these fetuses. The high risk of hypoxia and fetal death has to be balanced against that of extreme preterm birth with associated morbidity. The clinical
Background The cerebrospinal fluid (CSF) is involved in several diseases and patho- physiological states, such as Alzheimer’s disease and hydrocephalus. Previous studies CSF dynamics in the brain show that the flow of the CSF depends on cardiac pulsation, time of day and respiration. Methods In this thesis, the validity of using real time phase contrast MRI in order to study CSF flow is evaluated
This thesis is about the overlooked workload nurses’ hands are daily exposed to. This workload is made up of small tasks, seemingly requiring small efforts that together and over time can cause considerable muscle wear. A large number of these tasks consist of opening packages constructed to ensure that the products are sterile. In this study, the effects these packages have on the users were exam
The integration of peer support workers (PSW) into the mental health services workforce has offered additional avenues to strengthen service provision. In Sweden, the availability of peer support workers has grown significantly over the past decade, yet there has been insufficient investigation into their organization and implementation. Consequently, there is a growing need for further research i
Context: Breathlessness is associated with depression, but its relationship to anxiety or impaired function is less clear. Objectives: This study evaluated associations between chronic breathlessness and anxiety, depression, and functional status in the general population. Methods: This cross-sectional study of consenting adults (18 years and older) used an online survey. Quota sampling (n = 3000)
Lobbyists are working in an ambivalent atmosphere. In Brussels, lobbying is an activity occupying about 20 000 people on a daily basis. They are trying to influence the legislative outcomes from the work of the about 15 000 politicians and employees of the EU institutions (Coen 2007). On one hand the lobbyists are wanted and needed by the politicians and their civil servants. Previous research tel
Purpose: The aim of this study was to assess the performance-based visual ability among independently living elderly subjects and to investigate whether there was any association between visual ability and falls. Subjects and methods: A total of 298 randomly selected subjects aged 70-85 years were invited for an examination including monocular and binocular visual acuity (VA), contrast sensitivity
When trying to map the bibliometrics based ‘research evaluation landscape’ in terms of for instance methods, technical systems and stakeholders; the complexities soon become obvious. Different methods are used at different national and local levels; there is a great variation of systems used for gathering, organizing, and analyzing data; and a multitude of stakeholders, many of which taking on a v
This work presents an analysis of the physical properties of sub-micrometer aerosol particles measured at the high Arctic site Villum Research Station, Station Nord (VRS), northeast Greenland, between July 2010 and February 2013. The study focuses on particle number concentrations, particle number size distributions and the occurrence of new particle formation (NPF) events and their seasonality in
Biohythane is a hydrogen-methane blend with hydrogen concentration between 10 and 30% v/v. It can be produced from different organic substrates by two sequential anaerobic stages: a dark fermentation step followed by a second an anaerobic digestion step, for hydrogen and methane production, respectively. The advantages of this blend compared to either hydrogen or methane, as separate biofuels, are
Exacerbation frequency is central in treatment strategies for chronic obstructive pulmonary disease. However, whether chronic obstructive pulmonary disease patients from the general population with frequent exacerbations continue to have frequent exacerbations over an extended period of time is currently unknown. In this study, we aimed to investigate the stability of the frequent exacerbator in a
This presentation highlights results from a research study of ‘Music Week’; a one-week Swedish music project. The aim of the ‘Music Week’ project was to enable young people with physical impairments to take part in musical activities. Digitally-based musical settings were used in order to provide tools for performing and creating music. The main purpose of the present research study was to explore
Objectives. Chest pain is a common complaint in the emergency department (ED), and it is a challenge to identify low-risk chest pain patients eligible for early discharge. We aimed to develop a simple objective decision rule to exclude 30-day major adverse cardiac events (MACE) in ED chest pain patients. Design. We analyzed prospectively included patients presenting with chest pain. Low risk patie
ABSTRACT: BACKGROUND: Individuals with autism spectrum disorders (ASDs) often display symptoms from other diagnostic categories. Studies of clinical and psychosocial outcome in adult patients with ASDs without concomitant intellectual disability are few. The objective of this paper is to describe the clinical psychiatric presentation and important outcome measures of a large group of normal-intell
Objective – The role of the academic librarian has become increasingly educative in nature. In this study, the critical friend method was introduced among teaching librarians in an academic setting of medicine and health sciences to ascertain whether this approach could be implemented for feedback on teaching of these librarians as part of their professional development. Methods – We used a singl
BACKGROUND.: To better define subpopulations in which achieving adequate mycophenolic acid (MPA) concentrations quickly would be important, a post hoc exploratory analysis on the fixed-dose concentration-controlled database was performed, comparing high- versus low-risk renal transplant patients. METHODS.: Renal transplant patients were treated with mycophenolate mofetil, corticosteroids, and cycl
The main functions of estrogen are associated with reproduction. However, estrogen has been shown to be of functional importance also in non-classic target organs. Previous studies, especially epidemiologic and clinical ones, have addressed estrogen's influence on periodontitis, suggesting that estrogen has a beneficial effect, but the biological mechanisms have not been identified. Estrogen exert
Schema för KURSNAMN 10 p (15 ECTS) VT -2 2003 Schedule for GEOM05, 15 hp (15 ECTS credits) Autumn 2015 Magmatic petrology, Geochemistry and Geochronology Course leader: Ulf Söderlund & Anders Schersten Teachers: AG = Ashley Gumsley, CA = Carl Alwmark, AS = Anders Scherstén, SA = Sanna Alwmark, US = Ulf Söderlund E-mail to teachers: name.surname@geol.lu.se * = Excursion/fieldwork (assembly by gneis
https://www.geology.lu.se/sites/geology.lu.se/files/geom05_schema_ht1_2015.pdf - 2026-07-10
Lund University Course (e LUMES Master Thesis 2002/2003 Yan Borne’ The Environmental Impacts of the Olympic Games— Looking Forward to the Olympic Games 2008 in Beijing, China "The only environmentally sound Olympics would be no Olympics at all.” ---- Olav Myrholt, the Olympic project leader for the Norwegian Society for Conservation of Nature. By Yan Borne’ Supervisor Stefan Anderberg Master Thesi
https://www.lumes.lu.se/sites/lumes.lu.se/files/borne_yan.pdf - 2026-07-10
