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Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygou
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BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and
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Dysfunction in various parts of immune defence, such as immune response, immune complex clearance, and inflammation, has an impact on pathogenesis in systemic lupus erythematosus (SLE). We hypothesised that combinations of common variants of genes involved in these immune functions are associated with susceptibility to SLE. The following variants were analysed: HLA DR3, HLA DQ2, C4AQ0, Fcgamma rec
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Popular Abstract in Swedish Protein H - ett bakteriellt ytprotein med förmåga att binda till olika proteiner hos människa Bakgrund I vårt dagliga liv omges vi av bakterier av många olika slag. Flertalet av dessa är normalt ofarliga och många utgör den så kallade normalfloran hos människa. En del bakterier kan under vissa förhållanden ge upphov till infektion och sjukdom, men för att åstadkomma d
Course literature
Course literature is an important part of your studies. You can access the books you need by borrowing them from the library, buying them new or used, or using online resources. Planning ahead can help you save both time and money. Reading listsUniversity programmes and courses often have long reading lists. These are usually available at the start of the course and include the books you are expec
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Special-area-studies-schedule-spring-26
Special Area Studies, spring 2026 Special Area Studies ACCESSIBLE TO ALL EXCHANGE STUDENTS, SPRING 2026 SAS COURSES AT THE JOINT FACULTIES OF HUMANITIES AND THEOLOGY Information may be requested from: international@ht.lu.se | Webpage: www.ht.lu.se/en/international/ MONDAY A.M. SASH65 History of the Holocaust 19 January – 09 March 10.15 – 12.00 (Mon. and Thur.) Department of History, LUX SASH66 One