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Consumers want innovations that fulfil present and future needs and to be delighted! Hence the main objective of an innovation is to create value for the consumer/customer by a product, process, service or combinations, but is also important for manufacturers, suppliers and society, to promote growth, create new markets, answer new needs etc. The retailers now have the power in the supply - and va
The Japanese economy has since the beginning of the 1990’s suffered from a prolonged period of economic stagnation. Known as the Lost Decade, but extending its influence well into the 2000’s and beyond, many attempts has been made to reverse the stagnation. The latest of these has come to be known as Abenomics and is headed by incumbent Prime Minister Shinzō Abe. In this essay we investigate wheth
Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E
Tuning an ideal PID and then using its parameters in a real one, can yield undesired results. Nonetheless, many rules conceived for the ideal PID are successfully used in practice, owing to their greater flexibility. A systematic method would thus be useful to extend ideal PID tuning rules to the real PID, so as to preserve said flexibility while synthesising a realistic controller. This manuscrip
The problem of ‘naked statistical evidence’ is one of the most debated issues in evidence theory. Most evidence scholars agree that it is deeply problematic to base a verdict on naked statistical evidence, but they disagree on why it is problematic, and point to different characteristics of naked statistical evidence as the root of the problem. In this article, the author discusses the merits of dThe problem of ‘naked statistical evidence’ is one of the most debated issues in evidence theory. Most evidence scholars agree that it is deeply problematic to base a verdict on naked statistical evidence, but they disagree on why it is problematic, and point to different characteristics of naked statistical evidence as the root of the problem. In this article, the author discusses the merits of d
Partially Premixed Combustion (PPC) has shown its potential by combining high combustion controllability with emission characteristics that are close to those of an HCCI engine. In order to get PPC the ignition delay needs to be long enough for the fuel and air to mix prior to combustion. This can be achieved by injecting the fuel sufficiently early while running with high EGR.In order to find out
A diffusion process on complex networks is introduced in order to uncover their large-scale topological structures. This is achieved by focusing on the slowest decaying diffusive modes of the network. The proposed procedure is applied to real-world networks like a friendship network of known modular structure, and an Internet routing network. For the friendship network, its known structure is well
The main objective of this study is to introduce the new Sandvik’s production cost-model within Crushing & Screening (C&S) technology. So far, there have been different ways of determining different production costs in the industry, however, the previously published and presented methods have not been very efficient in calculating the costs per product and metric ton. Accordingly, the curr
Most studies that validate GFR equations present accuracy results stratified by measured GFR (mGFR; diagnostic correctness) or by estimated GFR (eGFR; diagnostic predictiveness) only, without a clear distinction in interpretation. The accuracy of a GFR equation is normally reported in percent (e.g. P30), but is often misinterpreted when stratified by eGFR. The aim of the study was to develop new a
