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Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.

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Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac

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Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl

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ABSTRACT IN ENGLISH Title: Why Pay When You Can Get It For Free? A quantitative study of the web-based music industry Seminar date: 4 of June, 2014 Topic/Course: FEKH19 Bachelors Thesis in Strategic Management, 15 University Credits Points (UPC) or ECTS-credits) Authors: Erika Fredriksson, Louise Klintner, Evelina Wennerberg Advisor: Christine Blomquist Key words: Web-based music services,

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The tendency to buy expensive and unnecessary goods is a pattern of consumer behavior that is becoming all too common in our society. We consume luxury items to satisfy practical needs that are already satisfied in the quest toward self-fulfillment, or simply to impress those around us. The phenomenon of “status consumption” has become increasingly evident in modern society. Although conspicuous c

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The aim of this Master’s thesis is to examine how students studying to become physiotherapists use the library’s website at the Medical Faculty at Lund University. We wanted to investigate whether the students were satisfied or not satisfied with the website’s structure and navigation and we also wanted to know how the students used the website and how well the website responded to the information

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Popular Abstract in Swedish Begreppet systemförvaltning började användas i början på 1970-talet. Ämnet har betydelse ur flera perspektiv. Systemförvaltningskostnaderna är som regel betydligt större än systemutvecklingskostnaderna, vilket kan veri¬fieras med flera undersökningar gjorda i olika länder och under en tidsperiod omfattande ett par decennier. Det vetenskapliga intresset för systemförvalt

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CAMBODIA NATIONAL LAW AND POLICY REPORT CONSULTATION DRAFT 2020 Displacement in the Context of Disasters and Climate Change Funded by This report was prepared by Victor Bernard (RWI) and Matthew Scott (RWI) 2020 TABLE OF CONTENTS 1 INTRODUCTION 1 1.1. A human rights-based approach 1 2 Displacement in Numbers 3 2.1. Number of disasters and people affected in the last ten years (2009–2018) 3 3 Recom

https://rwi.lu.se/wp-content/uploads/2024/03/Consultation-Draft_Cambodia.pdf - 2026-07-03

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Popular Abstract in Swedish Städer har kommit att framstå som alltmer drivande i arbetet med att ställa om till ett ekologiskt hållbart samhälle. Utöver att genomföra statliga direktiv eller fokusera på klassiskt kommunala uppgifter som fysisk planering eller renhållning, har kommunala politiker och tjänstemän alltmer kommit att driva en egen miljöpolitik på lokal nivå. Ett exempel är energi- och Local governments are increasingly taking the initiative in environmental governance. But can they make any difference in addressing current environmental challenges, which are becoming more and more global in scope? This PhD thesis explores and analyses the outcomes of proactive initiatives in the field of building energy efficiency, and the governance approaches taken. It addresses outcomes both

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BACKGROUND: Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome p