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This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580
Aurelija LukosevicieneAuthors and Creative UsersAddressing the Conceptual Challenges of Digital Creativity to EU Copyright Law from the Perspective of the AuthorDatum för disputation: fredagen den 1 oktober 2021Fakultetsopponent: Professor Ole Andreas Rognstad, Oslo universitetÄmne: civilrättAbstractTo be an “author” might mean many different things, depending on the context in which the word is u
https://www.jur.lu.se/forskning/disputationer/disputationer-2021 - 2026-06-25
9 juni 2026 13:15 till 14:00 | Exjobbspresentationer One Computer Science MSc thesis to be presented on 9 June Tuesday, 9 June there will be a master thesis presentation in Computer Science at Lund University, Faculty of Engineering.The presentation will take place in E:2116.Note to potential opponents: Register as an opponent to the presentation of your choice by sending an email to the examiner
https://www.cs.lth.se/evenemang/cs-msc-thesis-presentation-9-june-2026 - 2026-06-25
2013-08-29 1 Avtal för användning av datorutrustning vid Geologiska institutionen Jag har läst och accepterar att följa ”Regler för användning av datorutrustning vid Geologiska institutionen”, ”Regler för anslutning och användning av SUNET” samt ”Föreskrifter för användning av datornät vid Lunds universitet”. Datum: _______________________________________ Underskrift: _____________________________
https://www.geologi.lu.se/sites/geologi.lu.se/files/regelformular.pdf - 2026-06-25
The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh
Ash is produced in combustion of biomass. Sonic part of this matter is called fly ash and is carried by the flow and causes not only air pollution and erosion, but also call affect the thermal radiation. The effects of fly ash particles oil the thermal radiation are considered ill this investigation. By analyzing sampled data in all electrostatic filter, a realistic particle size distribution is f
Introduction: Umbilical cord blood measurement is the gold standard of evaluating neonatal metabolic status at birth. Dual sampling of cord blood vessels is clinical routine, yet the long-term value of venoarterial differences(ΔpH) is undetermined. The objective was to investigate the association of ΔpH, to long-term mortality and morbidity up to 20 years.Material and methods: This was a retrospecIntroductionUmbilical cord blood measurement is the gold standard of evaluating neonatal metabolic status at birth. Dual sampling of cord blood vessels is clinical routine, yet the long-term value of venoarterial differences (ΔpH) is undetermined. The objective was to investigate the association of ΔpH, to long-term mortality and morbidity up to 20 years.Material and methodsThis was a retrospectiv
Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel
The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl
In the equation for thermal energy output from a flat-plate solar collector (written as a function of the collector mean heat carrier temperature), both the gain and the loss terms are multiplied by the collector efficiency factor, F'. For a concentrating collector with an uneven (non-uniform) irradiation on the absorber, the efficiency factor for the gain term, here called the optical efficiency
In this paper the PreAmplifier ShAper (PASA) for the Time Projection Chamber (TPC) of the ALICE experiment at LHC is presented. The ALICE TPC PASA is an ASIC that integrates 16 identical channels, each consisting of Charge Sensitive Amplifiers (CSA) followed by a Pole-Zero network, self-adaptive bias network, two second-order bridged-T filters, two non-inverting level shifters and a start-up circu
The M protein of Streptococcus pyogenes is a major bacterial virulence factor that confers resistance to phagocytosis. To analyze how M protein allows evasion of phagocytosis, we used the M22 protein, which has features typical of many M proteins and has two well-characterized regions binding human plasma proteins: the hypervariable NH2-terminal region binds C4b-binding protein (C4BP), which inhib
The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren′s syndrome. To investigate whether NOD genes also promote autoimmune-mediatedarthritis we established a NOD strain with an MHC class II fragment containing the Aq class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contr
The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit
