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Type 2 Diabetes (T2D) is a disease of increasing importance and represents a growing burden on global healthcare and human health. In T2D, loss of effectiveness of insulin signaling in peripheral tissues cannot be compensated for by adequate insulin secretion, leading to hyperglycemia and resultant complications. In recent years, inflammation has been identified as a central component of T2D, both

This dissertation examines appropriations of five of Shakespeare’s tragedies (King Lear, Macbeth, Othello, Romeo and Juliet and Hamlet), written for the stage between 1979 and 2010 and set in Shakespeare’s playworlds. The aim of the study is to investigate how these appropriations are used as a strategy for discussing issues that are central both to Shakespeare’s plays and to the present gender-po

Firearm-related violence is common in our contemporary world and causes serious harm to humans as well as to the society. One of the countries in which firearm-related violence is increasing is Sweden and its most southern region, Skane, in which Malmo, Sweden's third largest city, is highly affected. If not contained and limited, Sweden risks becoming more and more violent.

Purpose: Stigma has been proposed to be one of the most serious obstacles to successful treatment, rehabilitation and inclusion in society of people with severe mental illness. An aspect of stigma which has been increasingly discussed is self-stigma, which refers to the internalization of negative stereotypes among people with severe mental illness. The aim of the present study was to investigate

It is well established that high ambient heat could cause congenital abnormalities resulting in miscarriage or stillbirth among certain species of mammals. However, this has not been systematically studied in real field settings among humans, despite the potential value of such knowledge for estimating the impact of global warming on the human species. This study sought to test the hypothesis that

Recent clinical trials have pioneered the successful use of a nonsteroidal immunosuppressive regimen and established a basis for application in a routine clinical setting. In this study, a single islet transplant was not sufficient to regulate blood glucose levels, and a second transplant became necessary. A similar observation was made in our macaque islet transplant study, where animals after th

Att kunna redovisa resultat ser vi i dagens samhälle som en självklar del av en organisations verksamhet. Privata profitdrivna företag liksom även alltmer offentliga organisationer styrs idag genom en marknadslogik som bland annat bygger på kontraktsbaserade uppdrag vilka förutsätter en granskning av hur de offentliga medlen används. Liknande krav på att utvärdera resultat och framgång blir i allt

Geoportals are increasingly used for searching, viewing, and downloading spatial data. This study concerns methods to improve the visual presentation in viewing services. When spatial data in a viewing service are taken from more than one source there are often syntactic, semantic, topological, and geometrical conflicts that prevent maps being fully consistent. In this study we extend a standard v

Bed joint reinforcement consisting of unprotected carbon steel was widely used to bridge windows and other openings in post-war brick buildings in the Scandinavian countries. Today, cracking caused by reinforcement corrosion constitute an increasing technical and economic problem, since removal of the corroding reinforcement can be both labour intensive and costly. Retrofitting measures are usuall

Current mobility patterns mean that many trips cross one or several municipal borders. This emphasises the need to integrate land-use and transport planning at regional functional scales. However, the Swedish planning system is characterised by a ‘municipal planning monopoly’, where local governments control the formal planning instruments. The lack of formal means for regional-level planning has

Purpose: The purpose of this study is to discuss the concept of information in relation to temporality within the context of climate change communication. Furthermore, the paper aims to highlight the empirical richness of information as a concept by analysing its use in context. Design/methodology/approach: The discussion is based on 14 semi-structured interviews with initiators and collaborators

Antibodies are central to acquired immunity against malaria. Plasmodium falciparum elicits antibody responses against many of its protein components, but there is also formation of antibodies against different parts of the red blood cells, in which the parasites spend most of their time. In the absence of a decisive intervention such as a vaccine, people living in malaria endemic regions largely d

OBJECTIVES: From a reproductive justice framework, we aimed to investigate how a possible association between hormonal contraceptive (HC) and antidepressants use (as a proxy for depression) is distributed across intersectional strata in the population. We aimed to visualise how intersecting power dynamics may operate in combination with HC use to increase or decrease subsequent use of antidepressa

Objectives: To analyse the living conditions and social outcomes (housing, engagement in employment or higher education, access to personal assistance and having a partner) in adults with cerebral palsy (CP) relative to their age, sex, communication ability, and motor skills. Methods: Cross-sectional registry-based study of 1,888 adults (1,030 males/858 females) with CP in the Swedish CP follow-up

Abstract: The aim of this chapter was to analyze associations between measures of cortisol in salivaand mental health and to see if divergent results were functions of the methods used. Measures ofmental health outcome included Major Depressive Disorder (MDD), symptoms of depression, andsymptoms of anxiety, Burnout (BO), and Vital Exhaustion (VE). Only studies on otherwise healthyindividuals were