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Background: C. pseudotuberculosis is an important animal pathogen that causes substantial economical loss in sheep and goat farming. Zoonotic infections in humans are rare, but when they occur they are often severe and difficult to treat. One of the most studied proteins from this bacterium, the secreted protein CP40 is being developed as a promising vaccine candidate and has been characterized as
Amplification of the HER-2/neu (HER-2) proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend to alter their phenotype during disease progression. Circulating tumor cell (CTC) analysis may serve as an altern
The reaction between the SO5– radical and MnII has been proposed to be the most important process for regeneration of MnIII in the MnIII/II-catalysed autoxidation of SIV in acidic aqueous solution. In the present study, the second-order rate constant for this reaction has been determined at pH 3. 0 and 10 mmol dm–3 ionic strength by use of pulse radiolysis. The study was performed in the presence The reaction between the SO5– radical and MnII has been proposed to be the most important process for regeneration of MnIII in the MnIII/II-catalysed autoxidation of SIV in acidic aqueous solution. In the present study, the second-order rate constant for this reaction has been determined at pH 3. 0 and 10 mmol dm–3 ionic strength by use of pulse radiolysis. The study was performed in the presence
Introduction: Atrial septal defect is the third most common CHD. A hemodynamically significant atrial septal defect causes volume overload of the right side of the heart. Preterm children may suffer from both pulmonary and cardiac comorbidities, including altered myocardial function. The aim of this study was to compare the rate of adverse events following atrial septal defect closure in preterm-
The circular economy (CE) is argued as a possible model for dealing with value chain instabilities in global production networks. Since geographical proximity is central to unlocking circular potential, x-shoring (including concepts like reshoring, resourcing, or friendshoring) is arguably key to this process. Often, spatial restructurings of the CE are embraced without a critical examination of t
De senaste årtiondena har samhället i stort präglats av digitalisering. Så också detaljhandeln, med en växande betydelse av digitala plattformar där människor gör sina vardagsinköp via dator, till alltmer även via mobilen. Avgörande för om människor faktiskt kan genomföra sina köp i detaljhandeln är betalningar. Betalningar har liksom detaljhandeln också blivit mer digitala, med en stadig minskninThis dissertation explores how and why certain payment methods are used in retail.Payment methods have changed in their form throughout history, and rapidly so in recent decades. Surprisingly, the treatment of payment in retail research appears detached from its purpose of use; i.e. purchasing products and services.Payment has a role to play in the digitalisation of society and is part of shaping
Increased concern was raised globally at the outbreak of COVID-19 that victims of domestic violence would be even more at risk when isolated with a violent partner and out of reach of support due to restrictions. Swedish staff in violence against women services prepared for increased calls for help. Instead, a worrying silence arose in a time and place of high uncertainty. This paper analyses the
In this paper, we explore the seeming stability of aging. More precisely, we offer an empirical account of how aging – images of aging, embodiments of aging, feelings about aging – is enacted in company practice, both in place and across time. Drawing on ethnographic fieldwork conducted at SMCare, a small-to-medium sized company active in the care technology sector, we show how aging achieves its
Background: Many patients with psychotic disorders have persistent paranoid ideation and avoid social situations because of suspiciousness and anxiety. We investigated the effects of virtual-reality-based cognitive behavioural therapy (VR-CBT) on paranoid thoughts and social participation. Methods: In this randomised controlled trial at seven Dutch mental health centres, outpatients aged 18–65 yea
This chapter explores the relationship between long-term exposure to neighborhood income inequality and adult mortality in Landskrona during a period of declining economic disparities. Using geocoded data from 1939 to 1967, the authors examine three interconnected hypotheses concerning income inequality and longevity. The analysis considers spatial changes in neighborhood inequality over time and
BackgroundTranscatheter aortic valve implantation (TAVI) is a percutaneous catheter-based treatment of aortic stenosis as an alternative to open heart valve surgery. In cases of TAVI endocarditis, the treatment possibilities may be limited as surgical removal of the infected valve may be associated with a high risk in elderly, comorbid or frail patients. The propensity of bacteria to form a biofil
Background: International research demonstrates an association between arts and culture activities and health and wellbeing. A similar association exists for sports event attendance and health. The aim of this study was to investigate associations between arts and culture engagement and attending sports events during the past year and self-rated health (SRH). Methods: A cross-sectional study. A pu
This explorative literature review aims to examine the content and methodologies of recent empirical studies on the aspirations of youth in situations of migration in Europe. The search yielded 30 peer-reviewed social science publications in English for the period 2010–2022, including both intra-European migrants ages 10–24 and youth with backgrounds from outside Europe. Contextual analysis was us
Background: Cities are restoring existing natural outdoor environments (NOE) or creating new ones to address diverse socio-environmental and health challenges. The idea that NOE provide health benefits is supported by the therapeutic landscapes concept. However, several scholars suggest that NOE interventions may not equitably serve all urban residents and may be affected by processes such as gent
How should democratic states approach and respond to secessionist movements using tactics contrary to the constitution to achieve their goals? What is the role of international human rights mechanisms in these processes? This article sheds light on these questions by examining how the UN Human Rights Committee approached and assessed two complaints that came before it in the wake of the Catalan De
Infection represents a complex interplay between invading microorganisms and the immune system. The immune system dynamically responds to the presence of pathogens, employing various defence mechanisms to neutralize and eliminate invaders. However, pathogens have evolved strategies to evade detection and elimination, leading to infections. This thesis focuses on mycobacterial regulation of macroph
The minority stress model has become a well-used framework to explain and analyse health among LGBTQ people, and specifically among transgender and gender-diverse people (TGD), when it is sometimes called ‘the gender minority stress model’. Scholars have argued the need for critical discussions about some of the assumptions underlying the gender minority stress model and how it has been used and d
In the context of a decarbonized future where stringent carbon dioxide (CO2) emissions constraints are imposed on vehicles, hydrogen emerges as a promising solution to address emissions directly at the point of use. This chapter explores the potential of using hydrogen to power vehicles, particularly in the context of heavy-duty (HD) internal combustion engine (ICE) applications. Hydrogen vehicles
