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Microsoft Word - 68284559-file00 10.1101/gr.147678.112Access the most recent version at doi: published online December 10, 2012Genome Res. Helen M Rowe, Adamandia Kapopoulou, Andrea Corsinotti, et al. cells necessary to preserve transcriptional dynamics in embryonic stem TRIM28 repression of retrotransposon-based enhancers is P
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/full_article.pdf - 2026-07-10
Strategic Plan - MultiPark StrategiC reSearCh area | lund uniVerSity PhotographerS: Kennet Ruona, Nina Ransmyr, Charlotte Carlberg bärg, Jens Persson, Laurent Roybon effort that has engaged many MultiPark co-workers and all our board members in an iterative process. The MultiPark strategic plan for 2014–2019 was ratified by the MultiPark Board in May 2014. We look forward to putting the strategic
https://www.multipark.lu.se/sites/multipark.lu.se/files/multipark_strategic_plan_2014-2019.pdf - 2026-07-10
Popular Abstract in Swedish Immunsystemet skyddar kroppen mot infektion. För att kunna skydda mot infektion krävs att immunsystemet är utrustat med kraftfulla biokemiska motmedel. Ett sådant motmedel är antikroppar. Antikroppar är proteiner som känner igen och specifikt binder till andra molekyler via en s k molekylbindande klyfta. När antikropparna har bundit in till en molekyl på t ex en bakteriPrimary infections and vaccination stimulates the immunesystem to produce memory cells that rapidly respond to reexposure of the same antigen. These memory responses are dependent on an adaptive type of immunity that sustains the reactivity of the immune system by long-lived memory immune cells. From an evolutionary perspective adaptive immunity as such appears to be restricted to jawed vertebrate
A very large majority of the current product development process models put forward in textbooks present a homogenous structure, what Ulrich & Eppinger [1] call the market-pull model, presented as a generic one, while other possible product development process models are merely seen as variants. This paper focuses on the task clarification and derived activities (mainly the systematic search f
In order to tap the energy saving and climate mitigation potential of the building sector, transaction costs of implementing energy efficient technologies need to be better understood and ultimately reduced. The objective of this paper is to identify and analyze the nature and scale of transaction costs resulting from the application of the passive house concept in energy efficient renovations. Re
The challenges for creating a greener economy and the institutional framework for sustainable development pass necessarily, or mostly, through cities, as they concentrate a large and growing part of the world’s economy and population, as well as decision-making power. With the processes of urbanization and rural-urban transformation, the economy in cities, especially in cities of developing countr
Popular Abstract in English Climate migration has become an iconic topic in international climate politics and policy. This work, combining political ecology, critical security studies and post-foundational theories, traces the changes of conflicting discourses across time and space, and assesses the different forms of security they interpellate. While initially attracting attention as a securityThis work seeks to de-naturalise climate-induced migration (CM). Combining political ecology and post-foundational theories, I read CM as a construct that reifies a series of phenomena into an issue to be researched and governed. By assessing the narratives, the knowledge, the logics and imaginaries on which conflicting discourses are built, I analyse the strategies of government they envision. I
The purpose of this thesis is to characterize the health status of the population in early Lund. This is pursued by an osteological analysis of 3.305 individuals fron three time periods: c. 990-1100, c. 1100-1300 and c. 1300-1536. The individuals derives from cemeteries connected to four neighbouring churches, where one is the sucessor of the other (Trinitatis). One cemetery (Kattesund) is by and
Abstract in Uncoded languages Tarptautiniai klimato kaitos susitarimai ir Europos Sąjungos teisės aktai veikia skirtingus valdymo lygmenis, įskaitant nacionalines teisės sistemas ir administravimo modelius. Disertacijoje iškeltas tyrimo klausimas – Kaip Lietuva, konkrečiai pramonės sektorius, įgyvendina šiltnamio efektą sukeliančių dujų (toliau – ŠESD) emisijų mažinimo reikalavimus, nustatytus KioInternational climate change agreements and the European Union legislation have an influence on different levels of governance, including national legal systems and administrative schemes. The following research question is addressed in the doctoral dissertation: “How does Lithuania, specifically the industrial sector, implement GHG reduction requirements under the Kyoto Protocol and the European
The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. This thesis, which is based on four original papers, deal with antibody d
This paper presents the development as well as the architecture of a computer-aided dedicated fixture design system intended to support the design of lightweight (carbon fiber composite) grippers for a major truck company. Lightweight grippers were required due to the increasing production rates in the automotive industry. The current robotic equipment was facing diverse problems during transporta
Popular Abstract in Swedish Är ledgångsreumatism en immunreaktion mot brosk? Kroppens immunförsvar bygger på ett antal olika vita blodkroppar, immunceller, som cirkulerar i blod och lymfa på spaning efter främmande och farliga "angrepp". Immuncellerna sägs svara på "angrepp", sådana immunsvar dirigeras av s k T-hjälparceller (Th-celler). Th-cellerna kommer från benmärgen, men de blir inte funktioThis thesis is based on work trying to understand the normal and pathological interactions taking place between the immune system and cartilage, specifically involving the cartilage-specific protein typ II collagen (CII). The work has been carried out in an experimental model of rheumatoid arthritis namely collagen type II induced arthritis (CIA) in mice. CIA can be triggered in mice of certain MH
Recently, semiotics has begun to be related to computing. Since semiotics is about the interpretation of signs, of which language is a chief part, such an interest may seem quite reasonable. The semiotic approach is supposed to bring semantics to the computer. In this paper I discuss the realistic in this from the point of view of computers as linguistic systems, that is, as interpreters of descri
Numerical analysis, such as the finite element method is the most used computational procedure for nonlinear deformation and strength analysis of structures. In order to obtain meaningful results the material behaviour must be described and simulated accurately. Another important element in order to perform the simulation is a robust and accurate numerical integration algorithm. The present paper
The 2008–2009 global financial crisis triggered ‘Green Energy Economy’ (GEE) policy packages to stimulate green growth in many countries. China soon became a leader and, supported by its 11th Five-Year Plan (2006–2010), devoted approximately one-third of its US$ 647 billion stimulus package to green energy technologies. Since then, numerous policy instruments have been implemented to encourage ‘Gr
The end of the Cold War and the subsequent dismantling of the Soviet Union has brought about fundamental changes in the Baltic Sea region in the last decade. In view of these developments, this article addresses two central questions when it comes to Baltic Sea security—how can the current peace in the Baltic Sea region be characterized and what are the prospects and problems involved in achieving
During recent years a couple of emergencies have affected the city of Malmo and its inhabitants and forced the city management to initiate emergency responses. These emergencies, as well as other incidents, are situations with a great potential for learning emergency response effectiveness. There are several methods available for evaluating responses to emergencies. However, such methods do not al
A role for regulatory lymphocytes has been demonstrated in the pathogenesis of type I diabetes in the NOD mouse but the nature of these cells is debated. CD1d-restricted NKT lymphocytes have been implicated in this process. Previous reports of reduced diabetes incidence in NOD mice in which the numbers of NKT cells are artificially increased have been attributed to the enhanced production of IL-4
This thesis is focused on natural killer (NK) T cells. NKT cells recognize lipids and glycolipids, rather than peptides, in the contents of the antigen presenting molecule CD1d. NKT cells have a surface phenotype reminiscent of memory cells, and have been shown to rapidly produce large amounts of cytokines, such as IL-4 and IFN-gamma, upon activation. Because of their rapid response to activation,
