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Objective: To investigate the prevalence of voice disorders in the general population. Study design: Analysis of data from the Stockholm Public Health Cohort. Methods: A public health survey was distributed to an open cohort of 114,538 adults >18 years of age in the area of Stockholm County, Sweden. The survey included one question about voice problems, estimating the extent of occurrence of voice
Regional innovation policies are often applied in a standardized way oriented at best practice models developed elsewhere. These policies fail to take specific sectoral and regional characteristics sufficiently into account. However, innovation processes and problems vary for firms in particular sectors since these exhibit distinct features dependent on their knowledge base. Also, companies are lo
ExtendJ (formerly JastAddJ) is an extensible Java compiler, supporting full Java source-to-bytecode compilation. ExtendJ enables researchers and developers to easily build powerful language extensions, custom static analyses, and other tools for Java. ExtendJ is built with Reference Attribute Grammars and Aspect Oriented Programming, enabling easy extension development.
Deterministic lateral displacement (DLD) is a powerful bimodal separation scheme [1] based on regular obstacle arrays that in its basic embodiment sends particles in two different directions as a function of size. We add functionality to the technique by including gravitational forces, as a perturbation to particles transported by fluid flow, and as a way of transporting the particles through a st
Conventional fractionation techniques fail to fully benefit from the variety in morphology and shape that is found among biological particles. Although light scattering in conventional FACS gives some information on the size and morphology of a particle, it is generally not capable of giving a definite number on specified dimensions of a small object. We demonstrate an approach where we select whi
We very briefly discuss proposed in the literature possible scenarios for intermediate mass black holes formation in globular clusters. We also discuss the results of the MOCCA simulations of about 2000 models (BigSurvey) regarding the distribution of events connected with electromagnetic and gravitational radiations, namely: mass transfer on IMBH, collisions and mergers with IMBH and mergers with
OBJECTIVE: Maternal hemodynamics in pregnancy is associated with fetal growth and birth weight, which in turn is associated with offspring cardiovascular disease later in life. We therefore sought to quantify the extent to which birth weight is associated with cardiac structure and function in adolescence.METHODS: Participants (N=1,964, 55% females) from a UK birth cohort were examined with echoca
Up to 80% of adolescents have experienced trauma and one‐in‐seven suffer from post‐traumatic stress disorder (PTSD), a chronic, debilitating psychiatric disorder. For 50% of these adolescents, the course of their illness is further complicated by a co‐occurring substance use disorder, which often develops from repeated self‐medication of PTSD symptoms. Once established, both disorders serve to mai
Immigration status as a ground of making distinctions that might be in violation of the right to non-discrimination, is conceptually underdeveloped. This gap is addressed by explaining how the European Court of Human Rights has chosen to use arguments shaped by factual and legal/normative elements to reason under Article 14 of the European Convention on Human Rights. One such argument concerns the
Background: Individualized cancer rehabilitation should be an integral part of cancer care. Contact nurses play a key role in identifying patient needs and coordinating evidence-based interventions to support rehabilitation. However, cancer rehabilitation remains marginal in current practice, as contact nurses face challenges due to the lack of systematic processes for assessment, intervention, an
The role of anti-epithelial growth factor receptor monoclonal antibodies (anti-EGFR MoAbs) in treatment-related electrolyte disorders is still controversial. Therefore, we conducted a meta-analysis of published randomized controlled trials (RCTs) to evaluate the incidences and overall risks of all-grade and grade 3/4 electrolyte disorder events. We searched relevant clinical trials from PubMed, EM
Israel’s surprise attack exposed the Islamic Republic’s staggering military vulnerability, eliminating top commanders and penetrating airspace with impunity. The regime’s collapse in air defense and intelligence is not merely operational, it reflects decades of corruption, ideological purges, and systemic decay. As the war unfolds, six scenarios emerge, including revolt and military coup.
INTRODUCTION: The FEV1 quotient (FEV1Q), calculated as the index between FEV1 and a theoretical lower survivable FEV1 threshold of 0.4L for females and 0.5L for males, has been investigated as a novel method of interpreting results from lung function testing. The applicability of the FEV1Q in populations with chronic respiratory failure has not been studied, and the continuous association between
Herpes simplex virus type 1 (HSV-1) delivers its genome into the host nucleus via docking of the viral capsid at the nuclear pore complex (NPC), a process mediated by the capsid vertex-specific complex (CVSC), composed of UL17, UL25, and UL36. While prior in vivo studies have implicated UL25 and UL36 in NPC interactions, their interpretation is complicated by indirect effects from viral traffickin
What happened in Dersim in 1937–38, in the early years of the Turkish Republic, is no longer a secret. In recent decades, Dersim has been recognised as at least a state-led “massacre”, mass graves have been discovered, and written and oral testimonies of both victims and perpetrators have come to light. However, a clear definition and recognition of this genocide, as well as reconciliation and res
Anoxic and hypoxic environments serve as habitats for diverse microorganisms, including unicellular eukaryotes (protists) and prokaryotes. To thrive in low-oxygen environments, protists and prokaryotes often establish specialized metabolic cross-feeding associations, such as syntrophy, with other microorganisms. Previous studies show that the breviate protist Lenisia limosa engages in a mutualisti
This study investigated the impact of a national palliative care policy introduced in 2013. The hypothesis was that end‑of‑life and palliative care policy shape healthcare services, which in turn influence service utilisation and ultimately place of death for people dying from cancer. The aim was to identify longitudinal trends in place of death for people with cancer in Sweden. A population‑level
The human brain is a complex and finely tuned organ, constantly monitored and maintained by its resident immune cells.Among these, microglia are the primary regulators of the brain immune environment under physiological conditions, and monocyte-derived macrophages contribute mainly to pathological states such as ischemic stroke and neuronopathic Gaucher’s disease (GD). These two diseases, although
Immune function varies widely across humans. Biological sex is a key factor underlying human immune variability, with men presenting with more severe infections and increased cancer rates, while women exhibit higher vaccine responses and prevalence of autoimmunity. Intrinsic biological sex differences arise from varying contributions of chromosomal sex, and sex hormone sensing and downstream signa
