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The purpose of this paper is to show how eye-tracking methodology can be used to study ‘inner space’; both from a theoretical point of view – the existence (or not) of internal image representations – as well as from an applied point of view – the usage of mental imagery in thinking and reasoning. First, we introduce the reader to the mental imagery debate. Second, we summarize studies on mental i
Large tropical (TROP) volcanic eruptions can influence North Atlantic climate by inducing a positive shift of the North Atlantic Oscillation (NAO), typically resulting in winter warming across northern Eurasia. However, these changes remain highly uncertain, as they may coincide with strong internal variability in Northern Hemisphere wintertime climate. In contrast, Northern Hemisphere extratropic
BACKGROUND: Although large studies and pooled analyses of individual patient data have demonstrated the safety of deferring coronary revascularization based on a nonischemic intracoronary pressure index result, conflicting findings have emerged in specific patient subsets and with varying follow-up. Thus, we conducted an updated comprehensive systematic review and meta-analysis to investigate the
Formation of calcium oxalate incrusts, scaling, may cause severe problems in the pulp and paper industry. Enzymatic degradation of oxalic acid provides a novel approach to eliminate the problems with calcium oxalate precipitation. The performance of two oxalate-degrading enzymes, oxalate oxidase from barley and oxalate decarboxylase from Aspergillus, was tested in model experiments with respect to
Burova L, Pigarevsky P, Seliverstova V, Gupalova T, Schalén C, Totolian A. Experimental poststreptococcal glomerulonephritis elicited by IgG Fc-binding M family proteins and blocked by IgG Fc fragment. APMIS 2012; 120: 221-30. The pathogenesis of acute poststreptococcal glomerulonephritis (APSGN), a major nonsuppurative complication of group A streptococcal (GAS) throat or skin disease, remains un
BACKGROUND Surgical site infections (SSIs) after dermatologic surgery cause pain, prolong healing, result in unaesthetic complications, and lead to excessive use of antibiotics. The pathogenesis of wound infections is complex and is dependent on bacterial load and diversity, among several factors. OBJECTIVE To investigate bacterial dynamics at dermatosurgical sites at different time intervals and
Autoantibodies against glutamic acid decarboxylase 65 (GADA) are found frequently in patients with autoimmune diabetes. Immunoglobulin (Ig)G(1) is the most frequent subclass among the GADA IgG subclasses. IgG(4) is a more common subclass in latent autoimmune diabetes in adults (LADA) at clinical onset compared to type 1 diabetes. The aim of this work was to study the different GADA-IgG subclass pr
Toll-like receptor signaling requires functional Toll/interleukin-1 (IL-1) receptor (TIR) domains to activate innate immunity. By producing TIR homologous proteins, microbes inhibit host response induction and improve their own survival. The TIR homologous protein TcpC was recently identified as a virulence factor in uropathogenic Escherichia coli (E. coli), suppressing innate immunity by binding
Billions of people are without access to surgical care, in part because of the inequitable distribution of the surgical workforce. Drawing on recently collected data for the number of surgeons, anaesthesiologists, and obstetricians worldwide, we sought to show their global maldistribution by identifying thresholds of surgical workforce densities, and by calculating the number of additional provide
Context: Long-term data are missing in GH-treated acute lymphoblastic leukemia (ALL) patients. GH therapy may result in poorer outcome regarding cardiovascular (CV) and particularly cardiac effects than in patients with hypothalamic-pituitary disease. Objective: Our objective was to evaluate GH therapy on CV risk, cardiac function, physical activity, and quality of life in ALL patients treated wit
Popular Abstract in Swedish År 2011 är det exakt 20 år sedan lärarkåren kommunaliserades. Reformen ger fortfarande upphov till diskussioner, inte minst från liberalt håll diskuteras idag lärarprofessionens status och vilka konsekvenser kommunaliseringen har medfört. I Professionens problematik analyseras motiven bakom kommunaliseringen. Historikern Johanna Ringarp visar att reformen var ett led i On 8 December 1989, the Swedish Parliament resolved that the state regulation of teaching positions would be terminated beginning on 1 January 1991. The parliament’s decision came on after fierce debates that took place in both teacher staff rooms and in public in 1989. Almost 20 years later, the reform still gives rise to controversy, and current political debates also touch on the possibility of
Water and salt mass balances for the Dead Sea were modeled. Precipitation, evaporation, river discharges, ground water flows, input/output from potash companies and salt production, and brine discharge were included in the models. The mixing time in the Dead Sea was modeled using a single-layer (well-mixed) a two-layer (stratified) system. Using the single-layer approach the water level was predi
Although estrogen receptor-alpha (ERalpha) is a marker used to identify breast cancer patients most likely to benefit from endocrine therapy, approximately 50% of ERalpha-positive breast carcinomas are resistant to tamoxifen. Preclinical studies have shown that phosphorylation of ERalpha at serine-118 (ERalphaS118-P) is required for tamoxifen-mediated inhibition of ERalpha-induced gene expression.
Vegetated roofs are becoming a trend in urban design, among others as a tool for city greening, mitigating urban heat island effect, and lowering urban storm runoff. Additionally, pollutant removal within vegetated roofs is often expected; however, it is commonly riot a design feature. This study investigated influence on runoff water quality from two fullscale vegetated roofs (an intensive from J
A role for Helicobacter pylori infection in the development of gastric cancer in humans is well established; however, evidence for its carcinogenicity in animals remains inadequate. Mongolian gerbils and mice are commonly used to investigate the carcinogenicity of H. pylori, yet it is unclear whether H. pylori infection per se causes gastric cancer or duodenal ulcers in these animal models. Gastri
IgG subclasses of glutamic acid decarboxylase (GAD(65)) antibodies (GADA) may reflect the immunological state in the pancreas of GADA-positive patients with autoimmune diabetes. The use of biotin-conjugated antibodies and streptavidin Sepharose are used commonly in immunoprecipitation assays (IPA) based on (125)I- or (35)S-labelled antigens to capture IgG subclasses directed against IA-2 or GAD(65
Levels of nonantigen-induced pro-inflammatory cytokines and prostaglandin in macrophages isolated from human leucocyte antigen (HLA)-matched type 1 diabetes mellitus patients, first-degree relatives and healthy controls were determined. We hypothesize that monocytes isolated from patients are sensitized or preactivated and therefore, have an altered response to in vitro stimulus compared with cont
Electron injection from the transition metal complex Ru(dcbpy)(2)(NCS)(2) (dcbpy = 4,4'-dicarboxy-2,2'-bipyridine) into a titanium dioxide nanocrystalline film occurs on the femto- and picosecond time scales. Here we show that the dominating part of the electron transfer proceeds extremely rapidly from the initially populated, vibronically nonthermalized, singlet excited state, prior to electronic
