Filtyp
The middle Holocene Hekla-S/Kebister tephra originates in the Hekla volcanic system on SW Iceland. The distal distribution of the tephra includes the Faroe Islands, Shetland and Central Sweden, indicating a main dispersal towards the east. The chemical composition of the tephra follows the pattern of other major eruptions of Hekla, and ratios between selected oxides may in some cases allow separat
Hepatitis A virus (HAV) was isolated from human faeces using a fetal rhesus monkey kidney cell line (Frhk-4). Infectious medium from passage 12 was used to inoculate a large (5000 cm2) microcarrier cell culture maintained in suspension. The microcarriers used were swollen, collagen-coated dextran beads on which it was easy to propagate Frhk-4 cells. Intra- and extra-cellular virus levels were assa
CagA seropositivity is an important risk factor for gastric adenocarcinoma and duodenal ulcer. However, CagA seropositivity is also found in Helicobacter pylori-seronegative subjects. Is CagA seropositivity in these subjects a sign of a past H. pylori infection, or does it represent a false-positive reaction? This study investigates the intensity of the CagA immune reaction and the variation in Ca
BACKGROUND. Prostate-specific antigen (PSA) is produced in high amounts by normal and malignant prostate cancer cells. PSA is a serine protease with substrates that include semenogelin I and II, insulin-like growth factor binding protein 3, fibronectin, and laminin. PSA, via its enzymatic activity, may play a role in growth, invasion, and metastasis of prostate cancer cells. Recent data also sugge
Popular Abstract in Swedish C-Med 100, en naturmedicin med immunomodulerande egenskaper Vårt immunsystem skyddar oss mot infektioner från bakterier, virus och parasiter. För att detta ska fungera behövs många olika egenskaper och idag delas immunsystemet in i två delar, en ospecifik och en specifik. Den ospecifika delen består av hud, slemhinnor, magsyra och olika celler som snabbt tar sig till etExtracts from the bark of the vine Uncaria tomentosa have anti-inflammatory, antiviral, antimutagenic and antioxidant effects. In this study, we evaluate the effects of an Uncaria tomentosa extract, denoted C-Med 100, on the cellular level of the immune system both in vivo and in vitro. Our results indicated that lymphocytes had significantly prolonged half life after in vivo supplementation with
The Proton Exchange Membrane (PEM) fuel cell has been investigated for a long time because it has a high power density, low emission, wide choice of fuel sources, etc. However, the performance of a stack of PEM cells degrades with respect to that of a single cell. This is mainly due to the introduction of the manifold in which supplies the reactants to individual cells. The manifold can induce an
In trying to understand any aspect of success and failure in information systems practice, concepts of organisational analysis become increasingly important. Many issues arise and must be dealt with when an information system is to be developed and implemented. In order to avoid information system failures information system analysts should adopt an approach, which exploits the intrinsic and conte
The category of interjections is claimed to be universally encountered across languages of the world; this status, however, does not exempt it of a most troubled linguistic history. Interjections have been classifieds both as word-like and sentence- (or utterance-) –like; they have been denied linguistic status or exiled at the periphery of language as a bizarre, primitive form of communication, a
I understand patronage principally as a work of cultural and material support - the support shich was necessary to stage the performance of a piece of music in mayn different contexts. I focus on the fate of an opera, Richard Wagner's Parsifal, a work which was not performed at the Bayreuth festival between 1939 and 1944 because of its emphasis on reconciliation, non-violence and faith, but which
The overarching aim of this thesis was to contribute to the existing knowledge on the use of assistive devices in everyday life, by adding the perspective of very old single living people in a European context, namely Latvia and Sweden. The aim was to investigate the socio-demographics and environmental and health aspects that impact on device use in the two national contexts. A further aim was to
Although estrogen receptor-alpha (ERalpha) is a marker used to identify breast cancer patients most likely to benefit from endocrine therapy, approximately 50% of ERalpha-positive breast carcinomas are resistant to tamoxifen. Preclinical studies have shown that phosphorylation of ERalpha at serine-118 (ERalphaS118-P) is required for tamoxifen-mediated inhibition of ERalpha-induced gene expression.
Objectives: To study: (I) work-loss seen as sick leave and disability pension before and after the start of first anti-TNF therapy in Swedish regional and national RA cohorts; (II) baseline predictors of a good future work prognosis at diagnosis and after anti-TNF start with a special focus on the impact of the disease activity level and the disease duration at treatment start. Methods: RA patie
The 1st International Hip-related Pain Research Network meeting discussed four prioritised themes concerning hip-related pain in young to middle-aged adults: (1) diagnosis and classification of hip-related pain; (2) patient-reported outcome measures for hip-related pain; (3) measurement of physical capacity for hip-related pain; (4) physiotherapist-led treatment for hip-related pain. Thirty-eight
Monoclonal antibodies targeting CD20 are central in the treatment of B-cell lymphomas. In diffuse large B-cell lymphoma (DLBCL), inactivating mutations of the histone acetyltransferases CREB-binding protein (CBP) and EP300 are common. Moreover, knockdown of CBP in DLBCL has been shown to result in aberrant transcriptional silencing. Expression of CD20 is sensitive to epigenetic manipulation, and h
As a result of the huge economic and industrial development that human has been experiencing for decades or centuries, there are millions of potentially contaminated sites around the globe. Potentially contaminated sites are those which industrial, agricultural, mining and waste containment activities with potential to contaminate soil and groundwater has taken place in. A small number of these co
Background: Basal cell carcinoma (BCC) is the most common skin cancer form, and one first-line treatment is surgical excision. Complete excision is vital to minimize risk of recurrence. Studies on occurrence of incomplete excisions have given diverse results and seldom include large populations from a dermatological setting. Objectives: The rate of positive surgical margins in primary surgery of B
Modeling criteria interaction in decision-making problems is complex and often neglected. In complicated problems, like contaminated site remediation projects, independency of involved criteria is not a realistic assumption. INfluence based deciSIon guiDE (INSIDE) is a methodology that enables sustainable decision making and management in contaminated site remediation practice. Unlike most previou
