Filtyp
Sweden succeeded in remaining a non-combatant through the First World War. However, the conflict affected the nation in many ways, for example in terms of film production and film consumption. The Swedish film industry was growing rapidly already before the outbreak of the First World War. The number of cinemas increased every year. It is estimated that there were 700 cinemas in Sweden in 1919, tw
4-Quinolones affect mammalian cellular functions in vitro in several ways. High concentrations inhibit DNA replication, but individual genes are perhaps sensitive to lower concentrations of drug. Inhibition of cell proliferation differs widely among 4-quinolones. Ciprofloxacin and norfloxacin are the most antiproliferative, inhibiting cell growth by -30% at 20 mg/L. Genotoxicity tests with 4-quino
The aim of this study was to delineate management zones by using topographical data, and to investigate how these management zones relate to soil parameters and yield. Elevation, as well as soil and yield data, were sampled in the field. Digital elevation models have been created, and the topographical parameters of slope, aspect and drainage area, estimated. Management zones have been delineated
Persuasion and manipulation have been central concerns of Critical Discourse Analysis since its beginnings (e.g. Hart 2014; Van Dijk 1996). Traditionally, the persuasive and manipulative potential of texts has been explored by means of interpretive analysis. However, the actual perlocutionary effects of the strategies identified through this process are rarely (if ever) evaluated empirically. This
Increasing evidence links intraneuronal β-amyloid (Aβ 42) accumulation with the pathogenesis of Alzheimer's disease (AD). In Aβ precursor protein (APP) mutant transgenic mice and in human AD brain, progressive intraneuronal accumulation of Aβ42 occurs especially in multivesicular bodies (MVBs). We hypothesized that this impairs the MVB sorting pathway. We used the trafficking of the epidermal grow
All infective bacterial species need to conquer the innate immune system in order to colonize and survive in their hosts. The human respiratory pathogens Haemophilus influenzae and Moraxella catarrhalis are no exceptions and have developed sophisticated mechanisms to evade complement-mediated killing. Both bacterial species carry lipooligosaccharides preventing complement attacks and attract and u
The human antimicrobial peptide LL-37 is produced by neutrophils and epithelial cells, and the peptide can be detected in plasma as well as saliva. LL-37 is active against both gram-positive and gram-negative bacteria including oral pathogens such as Porphyromonas gingivalis and Streptococcus mutans. Besides its antimicrobial properties, LL-37 modulates the innate immune system, and furthermore, i
BACKGROUND: Insomnia is a global problem and an important risk factor for patients living with cardiovascular disease (CVD), causing poor well-being and worsening disease prognosis. Yet, there is a lack of effective intervention strategies targeting sleep problems. To deliver patient-centered interventions and achieve good quality of sleep for this group, the own experiences of patients with CVD n
Objectives To examine the long term mortality associated with preterm delivery in a large population based cohort of women, and to assess for potential confounding by shared familial factors. Design National cohort study. Setting Sweden. Participants All 2 189 477 women with a singleton delivery in 1973-2015. Main outcome measures All cause and cause specific mortality up to 2016, identified from
Background: Chronic pain (CP) has serious medical and social consequences and leads to economic burden that threatens the sustainability of healthcare services. Thus, optimized management of pain tools to support CP patients in adjusting to their condition and improving their quality of life is timely. Although acceptance and commitment therapy (ACT) is considered an evidence-based psychological a
I avhandlingen skildras vardagslivet hos en grupp unga som bor på landsbygden. Medan vardagen i regel ses som grå och trist visar avhandlingen hur unga gör den till något särskilt, meningsfullt och roligt, hur de gör förhöjd vardaglighet. Genom att studera ungas vardagsliv med etnografiska metoder och teoretisk nyfikenhet når studien kunskap bortom de problembeskrivningar som vanligtvis skildrar sToday, the terms ‘young people’ and ‘rural Sweden’ are automatically associated with problems. Young people are associated with various worrying issues, such as mental illness, stress, pressure at school, or internet risk. Being young and living in a rural community is often regarded as especially problematic. Rural life is thought dull, and bracketed with isolation, lack of meaningful activities,
The research area of climate field reconstructions has developed strongly during the past 20 years, motivated by the need to understand the complex dynamics of the earth system in a changing climate. Climate field reconstructions aim to build a consistent gridded climate reconstruction of different variables, often from a range of climate proxies, using either statistical tools or a climate model
Here we present the results from an intercomparison of multiple global gridded crop models (GGCMs) within the framework of the Agricultural Model Intercomparison and Improvement Project and the Inter-Sectoral Impacts Model Intercomparison Project. Results indicate strong negative effects of climate change, especially at higher levels of warming and at low latitudes; models that include explicit ni
It is unclear whether caregiving has an impact on the physical, mental and functional health of older caregivers. This study aimed to describe physical, mental and functional health in relation to family caregiving in old age (60+) over a six-year period. The study comprised 2,294 randomly selected individuals (60–96 years) from the Swedish National Study on Aging and Care, who answered the questi
Exposure to inorganic arsenic (iAs) is a risk factor for cancer. Alterations in mitochondrial DNA copy number (mtDNAcn) and telomere length (TL) have been associated with cancer risk. Two Argentinean groups were studied: A) Puna area of Andes and B) Chaco. Arsenic exposure was assessed as the sum of arsenic metabolites (iAs, MMA, and DMA) in urine (U-As) using HPLC-HG-ICPMS. MtDNAcn, TL, and genot
