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Pharmaceutical packaging is linked to important demographic changes. Aging ofpopulations is one of the demographic changes which has called for more attention, especially in well-developed countries. The increase in life expectancy represents a positive consequence of years of research, development of medications, and improvement in life habits. In spite of that, the growth in the number of people
The Tamaulipas tragedy in 2010 proved a turning point for transit migration politics. This was one of the worst massacres on Mexican territory, in which 72 undocumented migrants, mostly from Central America, were kidnapped, tortured, and their dead bodies piled up in a ditch at a local ranch in the northern Mexican state. With this event, transit migrants became visible through their experiences o
The MAX IV 3 GeV storage ring operates with beam of high current and ultralow emittance. These beam parameters in combination with the small effective aperture enhance possible collective beam instabilities. Three passive harmonic cavities are installed to introduce bunch lengthening and tune spread, leading to decoupling of the bunch spectrum from the machine effective impedance and mitigating in
Background and purpose — Clindamycin has not been compared with other antibiotics for prophylaxis in arthroplasty. Since 2009, the Swedish Knee Arthroplasty Register (SKAR) has been collecting information on the prophylactic antibiotic regime used at every individual operation. In Sweden, when there is allergy to penicillin, clindamycin has been the recommended alternative. We examined whether the
Although gamification is a popular term, the concept has rarely been applied to political studies. Therefore, this chapter provides an overview of the key features of gamification and offers an adapted definition of gamification suited to the study of electoral politics. To help illustrate this definition, two examples of gamification from recent campaigns are discussed: the uCampaign mobile appli
Avhandlingen närmar sig frågan om hur journalistiska praktiker underlättar konstruktionen av kändisstatus. Teoretiskt uppfattas kändisskap som en särskilt flytande form av social status baserat på medierad uppmärksamhet och engagemang. Journalistik studeras som en invitation att dela upplevelser, organiserade utifrån narrativa strukturer. De empiriska fallen som studeras i avhandlingen är två mång
In recent years the possibility to increase maximum length and weight of heavy goods vehicles to allow for High Capacity Vehicles (HCVs) has been debated in Sweden. Proposals to increase maximum weight to 74 tonnes, and length to 34m have caused controversy. Key arguments among proponents are that HCVs will bring about benefits, such as: increasing energy efficiency and decreasing CO 2 emissions,
Synovial fluid (SF) may contain cleavage products of proteolytic activities. Our aim was to characterize the degradome through analysis of proteolytic activity and differential abundance of these components in a peptidomic analysis of SF in knee osteoarthritis (OA) patients versus controls (n = 23). SF samples from end-stage knee osteoarthritis patients undergoing total knee replacement surgery an
Socialization plays an essential role in ensuring that newcomers to an organization enjoy greater productivity and also integrate well into their workgroups. Since the COVID-19 pandemic, enterprise social media (ESM) is increasingly being used in organizations as an informal socialization tool. However, the effectiveness of these tools in affording the necessary socialization opportunities and ena
Although the use of location-based data (location coupled with semantic information) within Geographical Information Systems (GIS) and from Earth Observation (e.g. satellite) sources has been long established for decision makers, this has only recently been reflected in the construction sector with a more recent move from Computer Aided Design (CAD) to Building Information Modelling. BIM has opene
The fatigue deterioration modeling for welded steel structures subjected to high cycle fatigue is presented in the current document. The aim of this paper is to formulate approaches based on actual research results for the phases fatigue crack initiation, fatigue propagation and fatigue failure. The physical characteristics of the approaches are discussed in combination with the associated uncerta
A reliability-based approach to inspection planning for welded steel structures subjected to high cycle fatigue is presented in the current document. Inspections are an effective means to control the progress of fatigue deterioration and the presented approach allows to determine the minimum required inspection effort so that the considered structure complies with the given risk acceptance criteri
The mechanisms underlying M. fortuitum-induced pathogenesis remains elusive. Using headkidney macrophages (HKM) from Clarias gariepinus, we report that TLR-2-mediated internalization of M. fortuitum is imperative to the induction of pathogenic effects. Inhibiting TLR-2 signalling alleviated HKM apoptosis, thereby favouring bacterial survival. Additionally, TLR-2-mediated cytosolic calcium (Ca2+)c
Twenty-four strains of Mobiluncus mulieris and 27 strains of Mobiluncus curtisii were tested with respect to 6 different biochemical characteristics: arginin-decarboxylase activity, beta-galactosidase activity, synergistic hemolysis with Staphylococcus aureus, hydrolysis of hippurate, migration through soft agar and reduction of nitrate. Antigens of the same strains, prepared by ultrasonication, w
This open-access book surveys how digital technology can contribute effectively to improving our understanding of the past, through a sensory engagement based on the evidence of material culture. In particular, it encourages specialists to consider senses and human agency as important factors in studying ancient space, while recognising the role played by digital tools in enhancing a human-centred
We investigate the possibility that the Sun could have been born in M67 by carrying out N-body simulations of M67-like clusters in a time-varying Galactic environment, and following the Galactic orbits of stars that escape from them. We find that model clusters that occupy similar orbits to M67 today can be divided up into three groups, which we call hot, depleted, and scattered clusters. Hot clus
We demonstrate that exceptional points exist in fully transparent, optically "effectively" biaxial, anisotropic micro-cavities, fabricated using an uniaxial cavity material with its axis inclined to the Bragg mirror growth direction. This is similar to the existence of singular (optic) axes in absorbing biaxial crystals, but the lack of time reversal symmetry is mediated by the mode broadening, i.
X-ray phase-contrast imaging by grating interferometry has in the past decades been established both at synchrotron radiation sources and at conventional x-ray tubes. Due to the sensitivity to x-ray phase shifting, contrast in soft tissue has been improved significantly and the possibilities to do virtual histology of tissue biopsies are being pioneered. Constraints in the design of a grating inte
