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Assistive robots have received considerable research attention due to the increase of the senior population around the world and the shortage of care-givers. However, limited attention has been paid to involving seniors in the de-sign process in order to elicit their attitudes and perceptions of having their own robot. This study addresses this issue. We conducted a workshop with 14 Swe-dish senio
A new approach for the classification of patients with Sjogren's syndrome (SS) has been recently proposed. Although these new criteria substantially differ from the American European Consensus Group criteria, which have represented the gold standard for the last decade, when compared with each other the two sets show a high statistical degree of agreement. However, the fact that two different crit
Syftet med avhandlingen är att beskriva och analysera hur Försäkringskassans organisationskultur har förändrats. Mer specifikt är syftet att fånga förändringarna i Försäkringskassans organisationskultur genom att studera tjänstemännens relationer, reaktioner och handlingsstrategier över tid. De centrala frågeställningarna är följande: ”Hur har försäkringskassans organisationskultur förändrats?”, ”In 2005, The Swedish Social Insurance Agency (Försäkringskassan), was reformed from being local county authorities to a nationalized and integrated organization. The aim of this thesis is to describe how Försäkringskassan’s organizational culture has changed. The key questions are: ”How has Försäkringskassan’s culture changed?”, ”How are the organizational culture perceived and handled by the empl
We report on recent advances on the computation of the matrix elements of the electroweak penguins Q(7) and Q(8) which are relevant for the DeltaI = 3/2 contribution to epsilon'(K) in the chiral limit. The matching of scale and scheme dependences between Wilson coefficients and these matrix elements is done analytically at NLO in alpha(S).
Autoimmune T cell responses directed against insulin-producing β cells are central to the pathogenesis of type 1 diabetes (T1D). Detection of such responses is therefore critical to provide novel biomarkers for T1D 'immune staging' and to understand the mechanisms underlying the disease. While different T cell assays are being developed for these purposes, it is important to optimize and standardi
CD46 is a cell surface complement inhibitor widely expressed in human tissues, in contrast to mice, where expression is limited to the testes. In humans, it has been identified as an important T cell costimulatory receptor, and patients deficient in CD46 or its endogenous ligands are unable to mount effective Th1 T cell responses. Stimulation of human CD4(+) T cells with CD3 and CD46 also leads to
Thioredoxin (Trx)-1 is a small, ubiquitously expressed redox-active protein with known important cytosolic functions. However, Trx1 is also upregulated in response to various stress stimuli, is found both at the cell surface and secreted into plasma, and has known anti-inflammatory and antiapoptotic properties. Previous animal studies have demonstrated that exogenous Trx1 delivery can have therape
A number of policy instruments are used in order to provide consumers healthy products produced in a proper way as regards environmental impacts. The policy instruments are mainly directed to enterprises and companies producing products. Such actors are often addressed in terms of laws or regulations and represent different actors in a production chain. Policy instruments and the way they are used
FELs are well known for generating highly coherent light with excellent brilliance. In order to improve FEL coherence we have to follow how coherence evolves along the undulator and determine the factors that influence it the most. This paper presents qualitative coherence features that shine new light on the importance of coherence studies in the design of an FEL. By simulating and then analyzing
BACKGROUND: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung cancer remains unclear. METHODS: We performed single and combined multiple instrumental variable Mendelian randomization analysis by an inverse-weighted method, in addition to a
This paper focuses on a reliability analysis of an offshore wind turbine support structure which is part of an assessment and monitoring framework for wind turbines in operation. The reliability analysis builds upon structural, loading, limit state and uncertainty models comprising design, production and erection data. This model basis facilitates the reliability analysis of the ultimate, the fati
A fundamental question for economic sociology is: how are prices set? In economic sociological theory, a price is generally conceptualized either in terms of the performative construction of economy (e.g. a market device), or in terms of co-ordinational effects of power relations between buyers and sellers (e.g. the effect of social structures and institutions). In this paper, I set out to show ho
IMPORTANCE Intensive follow-up of patients after curative surgery for colorectal cancer is common in clinical practice, but evidence of a survival benefit is limited. OBJECTIVE To examine overall mortality, colorectal cancer–specific mortality, and colorectal cancer–specific recurrence rates among patients with stage II or III colorectal cancer who were randomized after curative surgery to 2 alter
Evidence of the effectiveness of the tests used to diagnose Helicobacter pylori (H. pylori) in primary healthcare is limited. This cross-sectional study aims to assess the accuracy of tests used for to diagnose H. pylori infection in primary care patients and its relationship with gastroduodenal pathologies. Over 12 months, 173 primary care patients with dyspeptic symptoms were referred for upper
