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Mechanical stimuli such as tissue deformation and fluid flow are often implicated as regulators of mesenchymal stem cell (MSC) differentiation during regenerative events in vivo. However, in vitro studies have identified several other physical and biochemical environmental cues, such as substrate stiffness and oxygen availability, as key regulators of stem cell fate. Hypotheses for how MSC differe
Climate Emergency: Law, Policy, and Adjudication in the EU 9-10 May 2023, Lund 1 Conference Summary The conference ‘Climate Emergency: Law, Policy, and Adjudication in the EU’ was held in Lund on 9-10 May 2023, organized co-jointly by the EU Forum of Judges for the Environment (EUFJE) and Lund University with the support of the Lund Centre for European Studies (CFE) and the Association of Foreign
The aim of this study was to examine whether autoantibodies to: ZnT8-Tryptophan (ZnT8WA), ZnT8-Arginine (ZnT8RA) or ZnT8-Glutamine (ZnT8QA) correlated with C-peptide or other autoantibodies and to assess diagnostic sensitivity of ZnT8WRQA. Specimens from 270 newly diagnosed diabetic subjects (age 15--34 years) and after five 5 years duration of disease were examined. Four linear regression models
Popular Abstract in Swedish Bränslecellen uppfanns redan 1838, det kommersiella genombrottet dröjde till 2007, den framtida potentialen är mycket lovande Domedagsprofetior angående växthuseffektens betydelse för livet på jorden når oss via media allt oftare. Bränsleceller är mycket lovande för ett framtida miljövänligt samhälle. Hög energieffektivitet och inga utsläpp av koldioxid, kväveoxider elFuel cells are electrochemical devices that directly transform chemical energy into electricity. They are promising for future energy systems, since they are energy efficient, able to use renewable fuels and, when hydrogen is used as fuel, there are no direct emissions of greenhouse gases. Various improvements are made during the recent years, however the technology is still in the early phases of
Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associa
The invariant differential cross section for inclusive electron production in p+p collisions at root s=200 GeV has been measured by the PHENIX experiment at the BNL Relativistic Heavy Ion Collider over the transverse momentum range 0.4 <= p(T) <= 5.0 GeV/c in the central rapidity region (vertical bar eta vertical bar <= 0.35). The contribution to the inclusive electron spectrum from semileptonic d
We previously showed concordance between Goodpasture syndrome antibody binding and production of experimental glomerulonephritis using human chimeric proteins. We now examine a more limited aminoterminal region of alpha(3)( IV) non- collagenous domain ( NC1) and the impact of single amino acid ( AA) mutations of this region on glomerulonephritis induction. Rats were immunized with collagenase- sol
Background and aim: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreparable scarring of lung tissue, with most patients succumbing rapidly after diagnosis. The mevalonate pathway, which is involved in the regulation of cell proliferation, survival, and motility, is targeted by the bisphosphonate zoledronic acid (ZA). The aim of this study was to assess the antifibroti
LUDC-IRC Postdoctoral Program 2020 – Project 1 Fig.1 NT and axonal guidance signaling (slit2, Ach, ATP, Sema3, NE) from nerve cells and the mesenchyme promote islet cell migration and β cell clustering during development. NT and axonal guidance receptor genes are expressed in developing and adult β cells and loss of function mutants have altered adult β cell mass and islet morphology1-3. LUDC-IRC
https://www.ludc.lu.se/sites/ludc.lu.se/files/artner_project_1.pdf - 2026-07-23
Lund University Bioimaging Centre (LBIC) is Lund University’s central infrastructure for advanced bioimaging and translational imaging research within the Faculty of Medicine. Established in 2008, LBIC provides researchers with access to state-of-the-art imaging technologies and multidisciplinary expertise spanning biological scales from molecules and cells to whole organisms and humans.LBIC is cu
https://www.lbic.lu.se/about-lbic - 2026-07-22
Fruit flies and other miniscule flying insects often cause a nuisance in the kitchen areas of our dwellings. To mitigate the invasion of indoor insect pests, behavioral modifications using spatial repellents containing natural products are emerging as alternatives to chemical insecticides especially around the kitchens and food storage areas. However, the absence of standardized testing methods fo
The increased prevalence of obesity is causing challenges on individual and socioeconomic levels. Neuronal subtypes of the hypothalamus control appetite regulation through the secretion of peptide hormones and neurotransmitters. Our limited knowledge of early molecular patterning of the human hypothalamus sets a challenge to design human in vitro models for cellular studies and drug screening. In
An international course for postgraduate students In the autumn of 2027, the international PhD course on the Ecology of Animal Migration will run again. Invited and Lund-based international authorities in the field give lectures that cover different aspects of animal migration. PhD students working on animal migration and related animal movement topics are encouraged to apply. Animals move across
https://www.biology.lu.se/phd-studies/phd-courses/ecology-animal-migration - 2026-07-21
In this investigation, a gas chromatography/mass spectrometry (GC/MS)-based metabolomic protocol for adherent cell cultures was developed using statistical design of experiments. Cell disruption, metabolite extraction, and the GC/MS settings were optimized aiming at a gentle, unbiased, sensitive, and high-throughput metabolomic protocol. Due to the heterogeneity of the metabolome and the inherent
Segmental gain of chromosome 17q is the most common genetic aberration in high-risk neuroblastoma, but its role in disease progression is poorly understood. This study aims to address the contribution of 17q gain to neuroblastoma malignancy. We analyzed the genetic and transcriptional landscape of 417 neuroblastoma patients across various risk groups and clinical stages using multi-omic approaches
Massive MIMO enables a very high spectral efficiency by spatial multiplexing and opens opportunities to reduce transmit power per antenna. On the other side, it also introduces new challenges in tackling the power amplifier nonlinearity due to the increased number of antennas. The behavior of Out-of-Band radiation from PAs in Massive MIMO is non-trivial depending upon the applied precoding scheme,
Sequencing in tissues – Explore biological processes at the single base resolution with novel (micro-)fluidics Thesis Proposal In this project you will participate in an interdisciplinary research team with the goal of developing state-of-the-art sequencing technologies inside biological tissues. The specific goal of the thesis project is to develop and implement microfluidics coupled to microscop
https://www.nano.lu.se/sites/nano.lu.se/files/2022-01/MSc%20%20Fluidics_proposal2022.docx - 2026-07-23
Professor Contact details Email: lars [dot] harrie [at] mgeo [dot] lu [dot] se Phone: +46 46 222 01 55Organisation Department of Earth and Environmental Sciences (MGeo) Room number: GIS centre 104 Service point: 16 WebpageLars Harries profile in Lund University research portalOther affiliations Assistant programme director Surveying (M.Sc.Eng.) Member of Strategic Research Area eSSENCE: The e-Scie
https://www.nateko.lu.se/lars-harrie - 2026-07-22
Hepatitis A virus (HAV) was isolated from human faeces using a fetal rhesus monkey kidney cell line (Frhk-4). Infectious medium from passage 12 was used to inoculate a large (5000 cm2) microcarrier cell culture maintained in suspension. The microcarriers used were swollen, collagen-coated dextran beads on which it was easy to propagate Frhk-4 cells. Intra- and extra-cellular virus levels were assa
