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Objective: GH causes insulin resistance, impairs glycemic control and increases the risk of vascular diabetic complications. Sulphonylureas stimulate GH secretion and this study was undertaken to investigate the possible stimulatory effect of repaglinide and nateglinide, two novel oral glucose regulators, on critical steps of the stimulus-secretion coupling in single rat somatotrophs. Methods: Pat
Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been identified as the strongest genetic risk factors for type 2 diabetes (T2D). However, the mechanisms by which these non-coding variants increase risk for T2D are not well-established. We used 13 expression assays to survey mRNA expression of multiple TCF7L2 splicing forms in up to 380 samples from eight types of human tiss
The thesis deals with circuit-level aspects of CMOS buffer SRAMs where the data throughput rate is a more important metric than access time or storage capacity. One aspect is the increased write cycle related power consumption that is the consequence of a high write ratio combined with a long word-length. That is addressed through the invention of a new bit-line operation mode which allows lower
BACKGROUND AND OBJECTIVES: During the past 10 years several DNA-typing methods have been developed to complement routine serological typing for determination of polymorphisms in the ABO, RH, KEL, JK and FY blood group genes. However, the molecular basis of blood groups can differ widely between ethnic groups. The purpose of this study was to evaluate selected DNA-based methods for phenotype predic
Treatment of bladder cancer has seen few advancements in recent decades until the introduction of checkpoint inhibitors during the last few years. Bladder cancer diagnostics have been similarly impaired and the likely advent of novel treatments in the neoadjuvant setting will require new diagnostic tools in the preoperative setting in muscleinvasive bladder cancer.This thesis evaluates three diagn
The activity-regulated cytoskeleton-associated (Arc) protein is essential for synaptic plasticity and memory formation. The Arc gene, which contains remnants of a structural GAG retrotransposon sequence, produces a protein that self-assembles into capsid-like structures harboring Arc mRNA. Arc capsids, released from neurons, have been proposed as a novel intercellular mechanism for mRNA transmissi
Global China: Resistance and Adaptation - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of
https://rwi.lu.se/news/global-china-resistance-and-adaptation/ - 2026-07-21
“Human Rights and Corruption City Challenges and Possibilities” - WHRCF - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and
https://rwi.lu.se/events/human-rights-and-corruption-city-challenges-and-possibilities-whrcf/ - 2026-07-20
Inriktning matematik | Matematikcentrum Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i våra system. Dessa c
Inriktning numerisk analys | Matematikcentrum Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i våra system. D
Variant specific zinc transporter 8 autoantibodies (ZnT8A) against either arginine (R) or tryptophan (W) at amino acid (aa) position 325 of the zinc transporter 8 (ZnT8) has been identified in T1D patients. Reciprocal cross-over tests revealed differences in half-maximal binding to indicate variable affinity of patient ZnT8 autoantibodies. Insufficient recombinant ZnT8 variant proteins have preclu
Background and aim - The development of clinical manifectations due to an eroded or ruptured atherosclerotic plaque, or occluded vessel, are one of the major causes of death world wide. It has been known for some time that atherosclerosis develops due to retention and modification of LDL particles in the vessel wall and the subsequent triggering of the immune system. The research presented within
Background: Left-sided pancreatic cancer is associated with worse overall survival (OS) compared with right-sided pancreatic cancer. Although neoadjuvant therapy is currently seen as not effective in patients with resectable pancreatic cancer (RPC), current randomized trials included mostly patients with right-sided RPC. The purpose of this study was to assess the association between neoadjuvant t
Methods Newsletter 2016 issue1.pdf JANUARY 2016 Methods & Methodology Faculty News What’s this? The Methods and Methodologies Project This project entails both a Graduate School (GS) and a Faculty of Social Sciences component, and both parts began in September 2015. Who am I? My background is one that is interdisciplinary, international, and mixed- and multi-method. I am a sociologist, but I als
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/methods_newsletter_2016_issue1_2.pdf - 2026-07-22
Smoking cessation prolongs survival and decreases mortality of patients with non-small-cell lung cancer (NSCLC). In addition, epigenetic alterations of some genes are associated with survival. However, potential interactions between smoking cessation and epigenetics have not been assessed. Here, we conducted an epigenome-wide interaction an
Popular Abstract in Swedish Det är en viktig uppgift för samhället att förebygga HIV och STI (sexuellt överförbara infektioner) bland ungdomar. Under de första åren av 1990-talet, när denna studie genomfördes, ökade dessa infektioner på ett oroväckande sätt. Detta gällde särskilt klamydiainfektionerna och nästan 25% av studenterna vid Lunds universitet rapporterade att de hade haft en konstaterad Slowing the incidence of HIV and STI among young people requires that they change their sexual behaviours. There is evidence that community-based interventions that target multiple levels of influence can be effective. In community mobilization different segments and sectors of a population are directly involved in problem identification and in the design and implementation of programs. The proces
Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study 1Lindfors K, et al. Gut 2019;0:1–7. doi:10.1136/gutjnl-2019-319809 Coeliac disease Original article Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk
https://www.teddy.lu.se/sites/teddy.lu.se/files/metagenomics_of_the_faecal_virome_indicate_a.pdf - 2026-07-22
ORIGINAL PAPER Achieving Standardized Medication Data in Clinical Research Studies: Two Approaches and Applications for Implementing RxNorm Rachel L. Richesson & Susan B. Smith & Jamie Malloy & Jeffrey P. Krischer Received: 16 December 2008 /Accepted: 15 March 2009 /Published online: 3 April 2009 # Springer Science + Business Media, LLC 2009 Abstract The National Institutes of Health has proposed
https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_07_richesson_jms_2010.pdf - 2026-07-22
LUNDS UNIVERSITET Sida 1 av 7 HUMANISTISKA OCH TEOLOGISKA FAKULTETERNA PROTOKOLL Diarienummer STYR 2025/285 Sammanträdesdatum 2025-01-29 kl 09.15-12.35 Fakultetsstyrelsen HT Fakultetsstyrelsens sammanträde 2025-01-29 Ledamöter Närvarande Sara Håkansson, universitetslektor, prodekan Anamaria Dutceac Segesten, universitetslektor, prodekan Arthur Holmer, universitetslektor Fanni Faegersten, internati
https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/protokoll/FS/Protokoll_FS_2025.pdf - 2026-07-20
