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A recent genome-wide association study revealed a variant (rs2431697) in an intergenic region, between the pituitary tumor-transforming 1 (PTTG1) and microRNA (miR-146a) genes, associated with systemic lupus erythematosus (SLE) susceptibility. Here, we analyzed with a case-control design this variant and other candidate polymorphisms in this region together with expression analysis in order to cla
DIGITAL ANALYSIS OF CARDIAC ACOUSTIC SIGNALS IN CHILDREN Milad El-Segaier, MD Division of Paediatric Cardiology, Department of Paediatrics, Lund University Hospital, Lund, Sweden SUMMARY Despite tremendous development in cardiac imaging, use of the stethoscope and cardiac auscultation remains the primary diagnostic tool in evaluation of cardiac pathology. With the advent of miniaturized and po
Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population, predominantly women(1-4). A number of susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes and mutations is yet to be identified(5-9). We previously reported a susceptibility locus (SLEB2) for Nordic multi-case
Most proteins have evolved to function optimally in aqueous environments, and the interactions between protein and water therefore play a fundamental role in the stability, dynamics, and function of proteins. Although we understand many details of water, we understand much less about the protein-water interface. In this thesis we use molecular dynamics (MD) simulations to cast light on many struct
Popular Abstract in English Parasites and their host organisms have engaged in a desperate battle over millions of years to evolve strategies that enable continued survival of their respective species. Parasites require some key metabolites to be able to survive and reproduce inside the host that often results in damage to host, while host organisms attempt to limit or prevent this damage by severHaemosporidia is a well-studied group of parasites, which infect mammals, reptiles and birds and use blood sucking vectors for their transmission. By conducting natural population studies and experimental infections, We have been able to detect and quantify Haemosporidia from avian blood to investigate how these pathogens affect their avian hosts. We have used life history data of two long-term lo
We present a new methodology, which we call Single Pair of Observations Technique with Eddy Covariance (SPOT-EC), to estimate regional-scale surface fluxes of 222Rn from tower-based observations of 222Rn activity concentration, CO2 mole fractions and direct CO2 flux measurements from eddy covariance. For specific events, the regional (222Rn) surface flux is calculated from short-term changes in am
BACKGROUND: Germline polymorphisms can influence gene expression networks in normal mammalian tissues and can affect disease susceptibility. We and others have shown that analysis of this genetic architecture can identify single genes and whole pathways that influence complex traits, including inflammation and cancer susceptibility. Whether germline variants affect gene expression in tumors that h
The respiratory pathogen Moraxella catarrhalis is a human-specific commensal that frequently causes acute otitis media in children and stimulates acute exacerbations in chronic obstructive pulmonary disease patients. The exact molecular mechanisms defining host-pathogen interactions promoting pathogenesis are not clearly understood. Limited knowledge hampers vaccine and immunotherapeutic developme
Flood risk is a great global concern that is not only affecting developing countries, but threatens to undermine sustainable development also in the most affluent advanced liberal democracies. While political inertia is delaying much needed global change, efforts to reduce risk and adapt to a changing climate are growing on more local levels. However, floods tend not to be bounded by geopolitical,
Genetic diversity is the basis for evolutionary adaptation and selection under changing environmental conditions. Phytoplankton populations are genotypically diverse, can become genetically differentiated within small spatiotemporal scales and many species form resting stages. Resting stage accumulations in sediments (seed banks) are expected to serve as reservoirs for genetic information, but so
Range expansions can be shaped by sex differences in behaviours and other phenotypic traits affecting dispersal and reproduction. Here, we investigate sex differences in morphology, behaviour and genomic population differentiation along a climate-mediated range expansion in the common bluetail damselfly (Ischnura elegans) in northern Europe. We sampled 65 sites along a 583-km gradient spanning the
Interfaces play a crucial role in determining perovskite solar cells, (PSCs) performance and stability. It is therefore of great importance to constantly work toward improving their design. This study shows the advantages of using a hole-transport material (HTM) that can anchor to the perovskite surface through halogen bonding (XB). A halo-functional HTM (PFI) is compared to a reference HTM (PF),
The use of aluminum-magnesium (Al-Mg) alloy particle as energetic additive in solid propellants was previously shown to have many advantages over pure Al particle, such as relatively low ignition temperature, high reaction rate and low particle agglomeration rate. In this paper, the combustion of Al-Mg alloy in hot H2O/O2/N2 flows was experimentally studied using wires with a diameter of 200 µm. T
Group A streptococci have evolved multiple strategies to evade human antibodies, making it challenging to create effective vaccines or antibody treatments. Here, we have generated antibodies derived from the memory B cells of an individual who had successfully cleared a group A streptococcal infection. The antibodies bind with high affinity in the central region of the surface-bound M protein. Suc
ObjectivesThe formation of episodic memories is critically determined by how we visually sample the world over time via sequences of eye movements. Nonetheless, in the neuroscience of human memory, memory encoding has almost exclusively been studied in experimental paradigms where the study material is presented in a single fixed location on the screen, and where eye movements are treated as artif
The physical layer foundations of cell-free massive MIMO (CF-mMIMO) have been well-established. As a next step, researchers are investigating practical and energy-efficient network implementations. This paper focuses on multiple sets of access points (APs) where user equipments (UEs) are served in each set, termed a federation, without inter-federation interference. The combination of federations
Infrastructure barriers and high costs of alternative sustainable fuels constrain the global logistics sector's transition to decarbonization. This research investigates how logistics providers establish institutional trust in the 'Book and Claim' service, where the environmental benefits of sustainable fuels are spatially decoupled from the physical transport of goods. Because corpora
LL_SMMX38_eng_HT25_250514 Reading list for Sustainable Consumption (SMMX38), 7,5 credits. The reading list was approved by the Board of the Department of Service Studies 2025-05-14. The reading list is valid from 2025-05-14. Anantharaman, Manisha. (2018). Critical sustainable consumption: a research agenda. Journal of Environmental Studies and Sciences, 8(4), pp. 553-561. Doi:10.1007/s13412-018-04
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2025-05/LL_SMMX38_eng_HT25_250514.pdf - 2026-10-02
Centre for Retail Research at Lund University ANNUAL REPORT | 2018 2 ANNUAL REPORT CENTRE FOR RETAIL RESEARCH AT LUND UNIVERSITY 2018 3 ANNUAL REPORT CENTRE FOR RETAIL RESEARCH AT LUND UNIVERSITY 2018 Introduction Centre for retail research – the fifth year The centre for retail research has now been in existence for five years and, during the past year, we have wrapped up se- veral research proje
https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/annualreport-2018.pdf - 2026-10-02
AI utmanar humanistisk forskning AI utmanar humanistisk forskning Publicerad den 27 november 2023 Hur kan humanistiska forskare möta de utmaningar som ChatGPT och andra tillämpningar av generativ AI innebär? Humaniserad AI var temat för Huminfras första webbinarium som över 100 deltagare runt om i Sverige anmälde sig till. – Det är jätteroligt att så många ville delta. Ämnet engagerar! Det är ocks
https://www.humlab.lu.se/sv/article/ai-challenges-research-in-the-humanities/ - 2026-09-03
