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B cell lymphomas (BCLs) are a group of severe cancers, afflicting both men and women at different ages. Gene expression profiling (GEP), have during the latest decades fundamentally contributed to a better classification and biological understanding of the different BCLs. Most studies using GEP have analyzed mRNA from tumor tissue constituted of both tumor cells and non-malignant bystander cells.
Crystal phase control in single III-V semiconductor nanowires has emerged recently as an important challenge and possible complement to conventional bandgap engineering in single material systems. Here we investigate a supply interruption method for precise crystal phase control in single nanowires. The nanowires are grown by metalorganic vapor phase epitaxy using gold particles as seeds and are a
The rise of water-based electromagnetic devices opens up new possibilities for controlling electromagnetic performance due to the liquid state of crucial parts of the device. This letter proposes the siphon mechanism as a novel way to achieve reconfigurability in these types of electromagnetic devices. To demonstrate this, a simple polarization-reconfigurable device based on a siphon is introduced
BACKGROUND: Triticum aestivum (wheat) is one of the world's oldest crops and has been used for >8000 years as a food crop in North Africa, West Asia and Europe. Today, wheat is one of the most important sources of grain for humans, and is cultivated on greater areas of land than any other crop. As the human population increases and soil salinity becomes more prevalent, there is increased pressure
Expression of antibodies inside cells has been used successfully to ablate protein function. This finding suggests that the technology should have an impact on disease treatment and in functional genomics where proteins of unknown function are predicted from genomic sequences. A major hindrance is the paucity of antibodies that function in eukaryotic cells, presumably because the antibodies fold i
Amplification of the MYCN proto-oncogene serves as a key marker of aggressive disease and poor treatment outcomes in certain pediatric tumors originating from the nervous system, including neuroblastoma and medulloblastoma. However, the complex nature of the challenging MYCN protein underscores the urgent need for additional targets and therapies to tackle neuroblastoma and medulloblastoma. In thi
Anaerobic bacteria dominate the human normal microbiota but strikingly little is known about these commensals. Finegoldia magna is a Gram-positive anaerobe found in the skin and at other non-sterile body surfaces, but it is also an opportunistic pathogen. This study describes a novel protein designated FAF (F. magnaAdhesion Factor) and expressed by more than ninety percent of F. magna isolates. Th
The A rabidopsis thaliana protein kinase AtPDK1 was identified as a homologue of the mammalian 3-phosphoinositide-dependent protein kinase-1 (PDK1), which is involved in a number of physiological processes including cell growth and proliferation. We now show that AtPDK1 expressed in E. coli as a recombinant protein, undergoes autophosphorylation at several sites. Using mass spectrometry, three pho
G protein-coupled receptor 30 (GPR30) is a ubiquitously expressed receptor reported to bind and become activated by estrogen (17β-estradiol). However, the role of GPR30 as an estrogen receptor for rapid estrogenic signaling is not completely accepted, and controversies exist regarding the identity of the cognate ligand, signaling, and subcellular localization of the receptor. Expression of GPR30 i
This report deals with identification of multivariable linear systems of finite order from measurements of input-output signals when the outputs are corrupted by additive random noises. The input-output relations of such systems can be described by a vector difference equation. A canonical form for the matrix coefficients of this equation is proposed and its existence and uniqueness are shown. Thi
Bibliotekarie Kontaktinformation E-post: maria [dot] bjorklund [at] med [dot] lu [dot] se Telefon: +46 46 222 18 36 Mobil: +46 73 075 08 26Organisation Biblioteket Besöksadress: Sölvegatan 19, Lund Rumsnummer: BMC F1027 Hämtställe: 66 WebbplatsMaria Björklunds profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ All
https://www.lub.lu.se/internt/maria-bjorklund - 2026-07-09
Stimulation of rat adipocytes with insulin and isoproterenol results in serine phosphorylation and activation of the adipocyte cGMP-inhibited phosphodiesterase (cGI PDE), events believed to be important in the antilipolytic action of insulin (Degerman, E., Smith, C.J., Tornqvist, H., Vasta, V., Manganiello, V.C., and Belfrage, P. (1990) Proc. Natl. Acad. Sci. U.S.A. 87,533-537). Here we demonstrat
The recently discovered selective glomerular hypofiltration syndromes have increased interest in the actual elimination of molecules in the human kidney. In the present study, a novel human model was introduced to directly measure the single-pass renal elimination of molecules of increasing size. Plasma concentrations of urea, creatinine, C-peptide, insulin, pro-BNP, β2-microglobulin, cystatin C,
Experimental studies are carried out to investigate the jet impingement heat transfer in crossflow by liquid crystal thermography (LCT). The aim is to assess the possibility of controlling heat transfer by using a rib. The crossflow Reynolds number spans from 80,000 to 160,000 and the velocity ratio ranges from 1.0 to 2.8. The results show that the presence of rib can significantly modify the heat
Urinary Incontinence is a problem for many people which can give rise to both psychological and social issues. To their aid there are a range of incontinence products available in retail today. A customer concern is however possible malodor formation. Studies have shown that both urine and the bacterial flora can contribute to malodor but the impact of microbial behavior in incontinence products o
