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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192487 sökträffar

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In an organization where the safety level is high and incidents and serious accidents are very rare, a steady erosion of safety awareness and protective measures can occur, especially when productive demands rise. Thus, it is important to continuously identify and monitor aspects in the organization that can affect work performance and safety. In an ongoing joint research project between the LFV G

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Local CNS inflammation takes place in many neurological disorders and is important for autoimmune neuroinflammation. Microglial activation is strain-dependent in rats and differential MHC class II expression is influenced by variations in the Mhc2ta gene. Despite sharing Mhc2ta and MHC class II alleles, BN and LEW.1N rats differ in MHC class II expression after ventral root avulsion (VRA). We stud

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Background: Mantle cell lymphoma (MCL) is an aggressive disease with short median survival. Molecularly, MCL is defined by the t(11;14) translocation leading to overexpression of the CCND1 gene. However, recent data show that the neural transcription factor SOX11 is a disease defining antigen and several involved signaling pathways have been pin-pointed, among others the Wnt/β-catenin pathway that

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OBJECTIVES: Venous thromboembolism (VTE) is a common worldwide disease. The burden of multimorbidity, that is, two or more chronic diseases, has increased. Whether multimorbidity is associated with VTE risk remains to be studied. Our aim was to determine any association between multimorbidity and VTE and any possible shared familial susceptibility.DESIGN: A nationwide extended cross-sectional hypo

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The aim of this study was to determine, through a genome-wide association study (GWAS), the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis (SSc). We considered limited (IcSSc) and diffuse (dcSSc) cutaneous involvement, and the relationships with presence of the SSc-specific auto-antibodies, anti-centromere (ACA), and anti-topoisomerase I (ATA). Four GWAS

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The purpose of this study was to identify new prognostic biomarkers with clinical impact in malignant peripheral nerve sheath tumor (MPNST), a highly aggressive malignancy for which no consensus therapy exists besides surgery. We have used tissue microarrays (TMAs) to assess in situ expression of 14 cell-cycle-regulating proteins in 64 well-characterized MPNST patients: 36 sporadic and 28 with neu

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Extracellular signal-regulated kinase 2 (ERK2) is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. Passive transport of an ERK2 monomer through the nuclear pore is also reported to coexist. We attempted to characterize the cytoplasmic retention and nuclear translocation of fusion proteins between deletion and sit

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Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of blastocyst stage embryos, and upon differentiation into embryoid bodies (EBs) they recapitulate the genetic, cellular and morphological events occurring in early embryogenesis. Among several signalling pathways and inductive factors, the fibroblast growth factors (FGFs) and their receptors (FGFRs) have been shown to be impor

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Twenty-five isolates of nontuberculous mycobacteria isolated from the South Indian BCG trial area were analysed by high performance liquid chromatography (HPLC) for mycolic acid pattern. The chromatograms differentiated the isolates into four species, namely M. terrae complex, M. intracellulare, M. parafortuitum and M. fortuitum. Three strains were unidentified, one of which did not show any mycol

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Definitive hematopoiesis emerges via an endothelial-to-hematopoietic transition in the embryo and placenta; however, the precursor cells to hemogenic endothelium are not defined phenotypically. We previously demonstrated that the induction of hematopoietic progenitors from fibroblasts progresses through hemogenic precursors that are Prom1+Sca1+CD34+CD45- (PS34CD45-). Guided by these studies, we an

antikroppar – Vetenskap och Hälsa

antikroppar – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: antikroppar Elakartad prostatacancer kan upptäckas med ny metod 2025-05-28 Prostatacancer (PCa) är den vanligaste cancerformen bland svenska män. Särskilt utmanande är stadiet med metastaser, där exist

https://www.vetenskaphalsa.se/tag/antikroppar/ - 2026-07-07

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Alten AB has a technology demonstator in the form of a motorized and camera equipped large scale labyrinth game. The ball position is controlled by a ABB industrial PLC connected with Android tablets for user interface and a camera as a sensor for the ball position. This thesis demonstrates the ability to place a wide angle camera inside the cabinet, correcting the lens distortion caused by the wi

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DC grids will play a key role in the future, interconnecting generation and load centers as well as energy markets. Large multi-terminal VSC-HVDC systems of high capacity will require automated coordination for several operation scenarios especially when operating under disturbances. With this in mind, and considering the dynamics of a DC system, communication loss events are considered severe dis

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The first study with a PID controller based automatic drug delivery system for propofol anesthesia in children is presented. It is shown that a robustly tuned PID controller is capable of delivering safe and adequate anesthesia. The design process of the control system is reviewed. Results are discussed and compared to those of two previous studies in adults.

Nyhetsbrev Juni 2024 (komplett)

Kära medlemmar i Nordic Network for Narratives in Medicine! Först och främst: Stort och varmt tack till er som medverkade i vårt nätverksmöte i Trondheim 13-14 juni och ett än varmare tack till briljanta organisatörer, ledda av Silje Haugen Warberg, Institutt for språk og litteratur, Norges teknisk-naturvitenskapelige universitet (NTNU)! Nyhetsbrevet läser ni i sin helhet i bifogad PDF, nedan i ko

https://www.medicinsk-humaniora.lu.se/sites/medicinsk-humaniora.lu.se/files/2025-05/Nyhetsbrev%20juni%202024%20(komplett).pdf - 2026-07-09

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The dynamics in a swirl-stabilized flame is studied using large eddy simulation (LES). We account for the effect of turbulence on the flame through a model based on a filtered flamelet technique. The model provides a consistent and robust reaction-diffusion expression for simulating the correct propagation of premixed flames. The filtered flamelet formulation has been implemented into a high-order