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Up to this date, only a few silk hydrogels were reported to be injectable. Of these, none are truly biomimetic, and are instead comprised of blends with limited amounts of silk. Hence, no truly silk-based hydrogels exist as of today. From the reported injectable matrices, only a few have considered the natural progressive acidification to which silk proteins are exposed before spinning. Adding to
Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type-specific regulatory landscape of human melanocytes, which give rise to melanoma but account for <5% of typical human skin biopsies, we performed an eQTL analysis in primary melanocyte cultures from 106 newborn males. We i
Coupled gas chromatographic (GC)–electroantennographic detection (EAD) analyses of ovipositor extract of calling Hessian fly, Mayetiola destructor, females revealed that seven compounds elicited responses from male antennae. Four of the compounds—(2S)-tridec-2-yl acetate, (2S,10Z)-10-tridecen-2-yl acetate, (2S,10E)-10- tridecen-2-yl acetate, and (2S,10E)-10-tridecen-2-ol—were identified previously
As the Human Proteome Project has outlined currently many research groups worldwide dedicated resources to focus on the completion of the human proteome catalogue. According to the project directives, not only all products of ca. 20,300 protein coding genes should be identified but also at least one splicing variant, one single nucleotide polymorphism product and some major post-translational modi
Fourier transform infrared (FT-IR) spectroscopy was applied to characterize the extracellular matrix (ECM) of kidney tumor tissue and normal kidney tissue. Freshly resected tissue samples from 31 patients were pressed on a CaF2 substrate. FT-IR spectra obtained from ECM of tumor tissue exhibit stronger absorption bands in the spectral region from 1000 to 1200 cm−1 and around 1750 cm−1 than those o
Cows produce saliva in very large quantities to lubricate and facilitate food processing. Estimates indicate an amount of 50–150 L per day. Human saliva has previously been found to contain numerous antibacterial components, such as lysozyme, histatins, members of the S-100 family and lactoferrin, to limit pathogen colonization. Cows depend on a complex microbial community in their digestive syste
The presence of 5-methyluridine (m5U) at position 54 is a ubiquitous feature of most bacterial and eukaryotic elongator tRNAs. In this study, we have identified and characterized the TRM2 gene that encodes the tRNA(m5U54)methyltransferase, responsible for the formation of this modified nucleoside in Saccharomyces cerevisiae. Transfer RNA isolated from TRM2-disrupted yeast strains does not contain
https://www.ht.lu.se/serie/2969083/ - 2026-07-02
This thesis covers the estimation of the fracture behaviour of the European woodspecies Norway spruce and birch. The fracture behavior of wood can be quantifiedthrough three material parameters: the stiffness, the strength, and the specific fractureenergy. In the present work, these parameters are characterized through two methods.The first method is purely experimental and only estimates one para
Mysteriet med akut svår hepatit – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Mysteriet med akut svår hepatit 2022-11-04 Gülsen Özkaya Sahin blev snabbt inolverad i jakten att få svar på varför barn drabbades av akut svår hepatit. Foto: Tove Smeds Slutet av januari, 2
https://www.vetenskaphalsa.se/mysteriet-med-akut-svar-hepatit/ - 2026-07-02
This paper presents a millimeter-wave (mm-wave) phase-locked loop (PLL), with an output frequency centered at 54.65 GHz. It demonstrates a mode-switching architecture that considerably improves the lock time, by seamlessly switching between a low-noise mode and a fast-locking mode that is only used during settling. The improvement is used to counteract the increased lock-time caused by cycle-slipsThis paper presents a millimeter-wave (mm-wave) phase-locked loop (PLL), with an output frequency centered at 54.65 GHz. It demonstrates a mode-switching architecture that considerably improves the lock time, by seamlessly switching between a low-noise mode and a fast-locking mode that is only used during settling. The improvement is used to counteract the increased lock-time caused by cycle-slips
With their potential to effectively address multiple urban sustainability challenges, the emerging policy discourse on nature-based solutions seeks to encourage the development of multifunctional nature for sustainable and just cities. Nature-based solutions, however, are vulnerable to co-option by powerful interests in ways that limit their contribution to a broad range of sustainability goals. R
Follicular lymphoma (FL) frequently transforms into the more aggressive diffuse large B cell lymphoma (DLBCL-tr), but no protein biomarkers have been identified for predictive or early diagnosis. Gene expression analyses have identified genes changing on transformation but have failed to be reproducible in different studies, reflecting the heterogeneity within the tumor tissue and between tumor sa
Antibody microarray based technology is a powerful emerging tool in proteomics, target discovery, and differential analysis. Here, we report the first study where recombinant antibody fragments have been used to construct large scale antibody microarrays, composed of 127 different antibodies against mostly immunoregulatory antigens. The arrays were based on single framework recombinant antibody fr
