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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193448 sökträffar

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Pancreatic polypeptide (PP) is a gut-derived hormone of the neuropeptide Y family that regulates appetite, gastrointestinal motility, and energy homeostasis through activation of the neuropeptide Y4 receptor (Y4R). With the rising prevalence of obesity, understanding the molecular pharmacology and structure-function relationships of PP-Y4R interactions is essential for the development of novel ant

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Samhället idag skakas av en våldsvåg vilket saknar motstycke i svensk historia. Skjutningar, sprängningar och dödligt våld inom den kriminella miljön har ökat kraftigt de senaste åren. Straffrättsliga åtgärder för att få bukt med gängbrottsligheten har följaktligen hamnat högt upp på den politiska agendan. Flera förslag som läggs fram i den offentliga debatten präglas av en mer offensiv brottsbekä

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This thesis focuses on how online activists react to online censorship imposed onto them by social media platforms and how the reactions shape the activists’ responses to the censorship. It does so by deploying a qualitative interview study design onto how Swedish individuals who advocate for Palestine online experience and respond to digital censorship on Meta’s social media platforms. In the st

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This work investigates the relationship between three different theoretical concepts related to the experimental values from this project. The first model includes critical micelle concentration (CMC) and surface tension. The second model incorporates surface dilational modulus with the amount of emulsifier. The third concept relates the Weber number, a dimensionless number which compares inertial

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In recent years, the development of meat-and dairy analogues has increased to meet demands from consumers, as well as serving as environmentally beneficial alternatives to meat and dairy. While traditional plant-based diets based on whole-foods have been shown to lead to beneficial health effects, the new analogues differ vastly from the ingredients of a whole foods, plant-based diet and the effec

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Denna uppsats undersöker det framväxande förhållandet mellan geografiska beteckningar (Geographical Indications, GI) och varumärken inom EU-lagstiftningen, med särskilt fokus på den rättsliga utvecklingen som mynnat ut i förordning 2024/1143. Även om både GI och varumärken utgör immate-riella rättigheter, tjänar de olika syften. Varumärken skyddar främst privata kommersiella intressen och företagsThis thesis explores the evolving relationship between geographical indica-tions (GIs) and trademarks within European Union (EU) law, with a particu-lar focus on the legal developments culminating in Regulation 2024/1143. While both GIs and trademarks are forms of intellectual property, they serve different purposes. Trademarks primarily protect commercial brand identity, while GIs are recognised

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The 2010s have raised questions about the influence of small central banks in an integrated economy. This thesis investigates the efficacy of the Swedish Riksbank and the effect of economic integration since the adoption of a floating exchange rate in 1993. Theoretically, I examine how financial integration and trade may impact the Mundell-Fleming trilemma. To investigate the impact of integration

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Background In prehospital patient care, numerous patients are examined, treated, and transported. Some are acutely seriously ill, while others, though not acutely ill, necessitate ambulance transport due to their inability to do so independently. Among the latter group, patients may be sicker than initially estimated. Objective This study aims to delineate the course of action for EMS clinician

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This experimental study investigates the effect of diversity initiatives on White individuals' perception of discrimination against minorities and whether this relationship interacts with their meritocratic values. With an increased global emphasis on diversity and inclusion, organizations strive to reduce discrimination and instead promote a culture that values diversity. However, the effecti

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In 2017, the #MeToo movement sparked a massive reckoning with a vast continuum of sexual abuse. From the moment the U.S. actress Alyssa Milano pressed the button ‘post’ on Twitter and unleashed a flurry of responses, the landscape of sexual misconduct allegations changed forever. Through social media platforms, #MeToo has provided a platform for marginalized voices to be heard, fostering a sense o

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The topic of the research is the representation of European diversities in the French-German cultural channel ARTE, specifically in its collection of documentaries from the Magazine Show ‘Regards: European Stories’, henceforth ‘Re: European Stories’ (2023-2024). By investigating the ways in which multiple dimensions of diversity - religion, politics, gender, ethnicity, race, disability, class and

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The global food system is a cause of the worldwide poly-crisis in climate change and ecological decay. Ecological food systems have been emerging to contest the ruinous food production model. This thesis explores one branch of ecological food production: urban farming. Focused on the Swedish context, cases in Växjö, Malmö, and Göteborg were analyzed to examine how urban farms and involved agents n

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The transition towards sustainable rail transportation has positioned hydrogen as a promising alternative to traditional fossil fuels. This thesis focuses on the analysis of design for onboard and offboard hydrogen storage systems for light trains, which plays an important role in facilitating the adoption of hydrogen-powered rail vehicles. It explores state-of-the-art hydrogen storage technolo

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The 2011 UN Guiding Principles on Business and Human Rights (UNGPs) introduced human rights due diligence (HRDD) as a societal expectation to businesses to implement a new kind of due diligence risk management process to ‘know and show’ they respect human rights. Ten years later, mandatory human rights due diligence (mHRDD) legislation imposing a legal duty to carry out HRDD has become mainstream

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Transposable elements (TE) are parasitic genetic entities that have the ability to alter their position within a genome and have the potential to influence its functionality. Although TEs play beneficial roles in the evolution of their host, they are active in various human disorders including neurological diseases, where may contribute to the progress of the disease. Long Interspersed Nuclear Ele

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In the present thesis, the interaction between atoms in superposition states and attosecond pulses is studied from the microscopic to the macroscopic regime. Using a semi-classical framework, three different models have been explored in order to investigate attosecond light--matter interaction processes. The first model is a microscopic, single-atom model. Through using this model, the absorptio

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This paper studies whether the level of IPO underpricing is enforced by increased firm complexity. Evidence from a sample of 215 Swedish IPOs between 2010–2020 suggests that investor’s ex-ante uncertainty increases as issuing firms become increasingly complex. As a consequence, firms exhibiting complexity generally experience higher degrees of IPO underpricing. Moreover, we find support for our cl

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Pancreatic cancer (PC) is a severe disease where only 8% of the patients survive longer than five years. Chemotherapy is the standard treatment option for patients with PC, either in adjuvant or palliative setting, however only 15% of the tumors are resectable. The poor prognosis highlights the need to identify new prognostic biomarkers and novel treatment options to improve patient outcome. This