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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192641 sökträffar

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OBJECTIVE:: To evaluate the prognostic implication of changes in postoperative B-type natriuretic peptide (BNP) concentrations in patients undergoing cardiopulmonary bypass for cardiac surgery. DESIGN:: A retrospective analysis of prospectively collected clinical data. SETTING:: Cardiothoracic surgery and an intensive care unit (ICU) in a university hospital. PARTICIPANTS:: The present study inclu

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Observational studies have shown inconsistent results for the association between blood pressure and cancer risk. We investigated the association in 7 cohorts from Norway, Austria, and Sweden. In total, 577799 adults with a mean age of 44 years were followed for, on average, 12 years. Incident cancers were 22184 in men and 14744 in women, and cancer deaths were 8724 and 4525, respectively. Cox reg

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Different types of progenitor and stem cells have been shown to provide neuroprotection in animal models of photoreceptor degeneration. The present study was conducted to investigate whether human neural progenitor cells (HNPCs) have neuroprotective properties on retinal explants models with calpain- and caspase-3-dependent photoreceptor cell death. In the first experiments, HNPCs in a feeder laye

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Thrombin generation is a key process that determines the extent of a hemostatic plug or a thrombotic process. The ensuing thrombin burst is crucial for the formation of a stable fibrin clot. During its active life, thrombin exerts a multitude of highly regulated actions on the blood and the vessel wall, including the clotting of fibrinogen. The inappropriate generation of thrombin may lead to path

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Abstract Therapeutic hypothermia (TH) is the only treatment available to reduce neurological sequels for unconscious patients following cardiac arrest (CA). TH requires sedation and muscular relaxation, obscuring the clinical neurological examination for estimation of prognosis, and clinical decision making. Continuous amplitude-integrated EEG (aEEG) has been used to predict outcome in neonates

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In two papers, Pekala et al. (2010a, 2010b) reviewed and empirically assessed the relationships among response expectancies, hypnotic suggestibility, spontaneous alterations in consciousness following a hypnotic induction, and hypnotic depth. We appreciate their attempt to integrate diverse facets of hypnotic responding and reconcile seemingly competing accounts of hypnosis. In addition, we applau

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The aim of the study was to investigate whether a supplement of antioxidants to subjects with a high working pace can influence the antioxidant capacity. The study was parallel and double blind with 98 subjects randomised into two groups. One of the groups was given a test drink with antioxidants for 4 weeks (450 ml/day) while the other group took a corresponding amount of placebo drink. The test

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Popular Abstract in Swedish Bildundervisningen i grundskolans tidigare år uppfyller inte de i Sverige uppsatta målen. De nationella utvärderingarna (NU 89) och (NU92) bekräftar detta. Lärarna säger att de saknar ämneskunskaper och utvärderingarna visar att inslag från äldre läroplaner präglar undervisningen. För att ge en bild av hur nuvarande problem kan ha uppstått presenteras i studien en histoThe art education in Swedish primary and secondary schools is far from perfect and as a result pupils seldom reach the desired standard. National evaluations in 1989 and 1992 confirm this. Teachers admit that they lack specific subject knowledge and evaluation reveals that many aspects of older curricula still prevail. The way in which the present problems may have arisen is described through the

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This thesis consists of an introductory chapter followed by four separate papers. The papers deal with various aspects of human capital, ability and migration. Using the Swedish Military Enlistment test, the first paper, Ability and Rates of Return to Schooling ? making use of the Swedish Enlistment Battery Test, estimates the return to schooling for individuals belonging to different parts of th

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Calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated anti-migraine efficacy. One remaining question is where do these blockers act? We hypothesized that the trigeminal ganglion could be one possible site. We examined the binding sites of a CGRP receptor antagonist (MK-3207) and related this to the expression of CGRP and its receptor in rhesus trigeminal ganglion. Pituitary

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Leaf and bark volatiles from nonhost angiosperm trees were tested on lps duplicatus by gas chromatographic-electroantennographic detection (GC-EAD) and by pheromone-baited traps in Sweden and Inner Mongolia, China, respectively. GC-EAD analysis of the headspace volatiles from fresh bark chips of Betula pubescens revealed trans-conophthorin, two green leaf Volatiles (GLVs): 1-hexanol and (Z)-3-hexe

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Vetenskapen likt andra verksamhetsområden existerar i växelspel med det omgivande samhället, i sitt historiska, sociala och psykologiska sammanhang. Något som även omfattar ekonomiska, politiska och kunskapsmässigt sammansatta grundvalar. På detta fundament vilar analysen i denna bok som förmedlar flera olika aspekter avseende vetenskapligt debatterande och vetenskapligt praktiserande. Boken ger i

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BRCA1 mutations, although implicated in disease predisposition in a major part of the hereditary breast cancer population, do not seem to be crucially involved in tumorigenesis of sporadic breast and ovarian cancers. This suggests that tumours arising in BRCA1 mutation carriers may differ from BRCA1 negative hereditary and sporadic cancer in genetic and biological features, as well as in clinical

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OBJECTIVES:: Individuals with chronic pain often report increased pain sensitivity compared to pain free individuals, so it is crucial to determine if and how different pain characteristics influence or interact with pain sensitivity. An alternative to experimental pain sensitivity testing is the self-reported pain sensitivity questionnaire (PSQ), that captures pain sensitivity in various body are

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Objectives. The aim of the study was to investigate older persons' experiences of using mobility devices. Methods. In this qualitative study, focus group interviews were carried out with participants living in two municipalities in the south of Sweden. Occupational therapists and physiotherapists identified interested participants, 65 years or older. A total of 22 persons participated once in the

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BACKGROUND: Pituitary tumours are common and easily treated by surgery or medical treatment in most cases. However, a small subset of pituitary tumours does not respond to standard medical treatment and presents with multiple local recurrences (aggressive pituitary tumours) and in rare occasion with metastases (pituitary carcinoma). The present European Society of Endocrinology (ESE) guideline aim

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The mechanisms and role of nerve cell death after traumatic brain injury (TBI) are not fully understood. The authors investigated the effect of pretreatment with the oxygen free radical spin trap alpha-phenyl-N-tert-butyl-nitrone (PBN) on the number of neurons undergoing apoptosis after TBI in rats. Apoptotic cells were identified by the TUNEL method combined with the nuclear stain, Hoechst 33258,