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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193168 sökträffar

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Almost 30 years have passed since gender studies entered archaeological discourse in earnest. What is the current status of gender research? One of the aims with this book is to contribute to answering this and other related questions. Another is to shed some light on the pasts and possible futures of gender research.Contributions deal with publication statistics in journals over the last theirty

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The primary goal of this paper was to uncover the drivers of digital transformation (DT) in the pharmaceutical industry. The Covid-19 pandemic and tightening regulatory standards in the global pharma industry necessitated pharma executives need to understand the most critical drivers of digitalizing the sector and charting a new path that improves production processes and streamlines these compani

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The food industry is very resource-intensive and continuously under stakeholder's scanner to address the impact of climate change, resource scarcity, ever-changing consumer demands and stringent legislations. It has resulted in the food industry adopting Industry 4.0 initiatives for changes. In this context, one of the key focus is on enhancing transparency through Augmented Reality (AR) experienc

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To optimize the workflow of civil engineering construction in a harbour, this paper developed a framework of the contaminant leaching assessment carried out on the stabilized/solidified dredged soil material. The specimens included the sampled sediments collected from the in situ fieldwork in Arendal and Kongshavn. The background levels of the concentration of pollutants were evaluated to assess t

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This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent p

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This thesis focuses on the removal of organic micropollutants and transformation products using ozone and activated carbon treatment processes. A combination of 14C-labeled and non-radiolabeled organic micropollutants was used to study aspects of micropollutant removal from novel perspectives. 14C-labeled ozone transformation products (OTPs) were generated by ozonation of 14C-labeled micropollutan

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The aTfaRel2/faRel2 operon from Coprobacillus sp. D7 encodes a bicistronic type II toxin-antitoxin (TA) module. The FaRel2 toxin is a toxic small alarmone synthetase (toxSAS) that inhibits translation through the pyrophosphorylation of uncharged tRNAs at the 3'-CCA end. The toxin is neutralized by the antitoxin ATfaRel2 through the formation of an inactive TA complex. Here, the production, biophys

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The behavioural variant of Alzheimer’s disease (bvAD) is characterized by early predominant behavioural changes, mimicking the behavioural variant of frontotemporal dementia (bvFTD), which is characterized by social cognition deficits and altered biometric responses to socioemotional cues. These functions remain understudied in bvAD. We investigated multiple social cognition components (i.e. emoti

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BACKGROUND: Both COVID-19 and its associated societal restrictions have affected individuals' health and everyday life. In Sweden, more lenient public health restrictions were implemented, with individuals asked to act responsibly in terms of reducing spread of disease. The majority of studies reporting on experiences of Covid-19 restrictions have been in the context of more substantial mandatory

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Background and aims: Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Mana

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Insurance can encourage the use of risk-increasing inputs, but it can also decrease people's incentives to exert effort when the latter is difficult to monitor. This effort reduction can be associated with a decrease in the use of effort-complementary inputs. I study a model of risk-sharing that allows for both effects of insurance on input use and use the latest ICRISAT panel to structurally esti

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Eyes in low-light environments typically must balance sensitivity and spatial resolution. Vertebrate eyes with large "pixels" (e.g., retinal ganglion cells with inputs from many photoreceptors) will be sensitive but provide coarse vision. Small pixels can render finer detail, but each pixel will gather less light, and thus have poor signal relative-to-noise, leading to lower contrast sensitivity.

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In this special issue of articles from leading neuroethologists—all of whom gave outstanding presentations within the Presidential Symposium of the 2022 International Congress of Neuroethology held in Lisbon, Portugal—we learn about the role of cryptochrome molecules in the magnetic sense of animals, how honeybees construct their honeycombs, why fish eyes are built the way they are in species from

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The guiding question of this paper is how (horizontal) connections are established when new items enter the network of constructions. It presents a quantitative, corpus-based study of the development of to-contraction (e.g. want to > wanna) in American English since the 19th century. From a plethora of earlier forms, gonna, wanna and gotta emerge, first as representations of phonetic reduction, bu

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Background: The distribution of ovarian tumour characteristics differs between germline BRCA1 and BRCA2 pathogenic variant carriers and non-carriers. In this study, we assessed the utility of ovarian tumour characteristics as predictors of BRCA1 and BRCA2 variant pathogenicity, for application using the American College of Medical Genetics and the Association for Molecular Pathology (ACMG/AMP) var

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Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. This thesis aims to address this issue by studying

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The theme of ICIS 2013 in Milan is "Reshaping Society through Information Systems" (http://icis2013.aisnet.org/). One aspect of reshaping society that has been recently discussed in central Europe is that of social inclusion (http://ec.europa.eu/social/main.jsp?catId=750&langId=en). Yet, after decades of research and ambitious political programs, we still observe an imbalanced treatment toward

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The significant environmental impact of the current fossil fuel-based industry is a major concern for society. Consequently, various initiatives are being undertaken to establish a more sustainable industrial model. One example is via the transition from conventional fossil fuel refineries to biorefineries, where renewable raw materials are utilised. Amongst these raw materials, the use of lignoce