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In the fusion-evaporation reaction Ca-40+Mg-24 at 104 MeV beam energy, excited states have been observed for the first time in the isotope Ga-31(61)30. The experimental setup comprised the Ge array CLARION, a recoil mass spectrometer and, in its focal plane, an ionization chamber. Five transitions in Ga-61 are identified, out of which a cascade of three transitions has been established by means of
Thrombomodulin (THBD) serves as a cofactor for thrombin-mediated activation of anticoagulant protein C pathway. Genetic aberrations in THBD have been studied in arterial and venous thrombosis. However, genetic changes in THBD and their role in the risk assessment of recurrent venous thromboembolism (VTE) are not well understood. The aim of the present study was to identify the genetic aberrations
Background: The FRAX® algorithm quantifies a patient's 10-year probability of a hip or major osteoporotic fracture without taking an individual's balance into account. Balance measures assess the functional ability of an individual and the FRAX® algorithm is a model that integrates the individual patients clinical risk factors [not balance] and bone mineral density. Thus, clinical balance measures
The risk of cancer in men from BRCA1 and BRCA2 families is relevant to define to motivate genetic testing and optimize recommendations for surveillance.
Spectral analysis as well as parametric identification techniques have been applied to data from boiling water reactor noise measurements to estimate the process dynamics. Three different parametric model structures were tried. Least squares and maximum likelihood methods were tried to estimate the parameters of the models. Low order models were obtained in most cases.The results show the difficul
Bifidobacterium longum endo-α-N-acetylgalactosaminidase (GH101), EngBF, is highly specific toward the mucin Core 1 glycan, Galβ1-3GalNAc. Apart from the side chains involved in the retaining mechanism of EngBF, Asp-682 is important for the activity. In the crystal structures of both EngBF and EngSP (from Streptococcus pneumoniae), we identified a conserved water molecule in proximity to Asp-682 an
Water resource recovery facilities face challenges with increasingly stringent effluent demands, complexity and demand for capacity increasing investments. Emerging technologies such as digital twins could alleviate these problems but require high frequency influent data. This work presents a method for utilising measurements in the primary clarifier effluent with a model of the processes between
Background: Older adults spend more time at home after retirement, and the home becomes a central place for activity. While research indicates that indoor lighting, exposure to daylight, physical activity and sleep interact to influence functioning, mood and daily rhythm, strategies are needed to promote behavioural changes to optimise these factors in daily life. The objective is to design an int
Retinal image motion could be due to movement of the observer through space or an object relative to the scene. Optic flow, form, and change of position cues all provide information that could be used to separate out retinal motion due to object movement from retinal motion due to observer movement. In Experiment 1 we used a minimal display to examine the contribution of optic flow and form cues.
Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. During stress, the cell can form cytoplasmic complexes of proteins and RNAs,
There exists an increasing demand for cost and time efficient cutting tests for describing the performance of different combinations of cutting tools and workpiece materials in the cutting process both in industry and academia. Cutting tools are expected to withstand the heat and the pressure developed during the machining of difficult to machine materials such as Ti6Al4V. This article introduces
Pili have only been discovered in the major Gram-positive pathogens in the past decade and they have been found to play an important role in colonisation and virulence. Pili have been shown to have many important functions including attachment to host tissues, mediating bacterial aggregation, biofilm formation and binding to proteins in the extracellular matrix. In this study, sortase-dependent pi
Background: Targeted viral load (VL) testing has been proposed for antiretroviral treatment (ART) monitoring in resource-limited settings. In this study, we have investigated the performance of the host biomarker galectin-9 (Gal-9), alone and in combination with interferon-γ-inducible protein 10 (IP-10), in identifying individuals at increased likelihood of viremia during ART.Setting:Cohort of HIV
Objective: Serum is usually added to growth media when mammalian cells are cultured in vitro to supply the cells with growth factors, hormones, nutrients and trace elements. Defined proteins and metal ions, such as insulin, growth factors, transferrin and sodium selenite, are sometimes also included and can in some cases substitute serum components. How adaptation to serum free media influences ce
Effective methods for locating formally protected capercaillie (Tetrao urogallus) lek sites in the Swedish forest landscape are essential for targeted conservation measures. This study aimed to develop a multi-scale habitat suitability model for capercaillie lek sites in the northern Swedish forest counties, and further evaluate its potential to identify priority areas for future field survey effo
Scintillation camera images contain a large amount of Poisson noise. We have investigated whether noise can be removed in whole-body bone scans using convolutional neural networks (CNNs) trained with sets of noisy and noiseless images obtained by Monte Carlo simulation. Methods: Three CNNs were generated using 3 different sets of training images: simulated bone scan images, images of a cylindric p
