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The possibility that the noradrenergic locus coeruleus system influences brain damage following ischemia was explored in rats. Bilateral lesions of the locus coeruleus projections to the forebrain aggravated the neuronal necrosis in the hippocampal CAI region and neocortex following complete cerebral ischemia induced by transient cardiac arrest. These findings provide evidence that the postischemi
The presence of focal EEG abnormalities in juvenile absence syndrome (JAS) may cause it to be misdiagnosed as focal epilepsy. The purpose of our study was to determine the presence of focal EEG abnormalities in patients with JAS and to ascertain whether some clinical features or antiepileptic drugs (AEDs) have an effect on focality. Serial EEGs of 52 consecutive patients with JAS were retrospectiv
Metallothionein is a protein with affinity for metals and is present in several tumors. We examined its immunohistochemical expression in 37 resected primary liver tumors and 117 colorectal metastases. The reaction was intense in the two fibrolamellar hepatocellular carcinomas and in many of the hepatocytes of the pseudotumor case of focal nodular hyperplasia. The reaction was low or moderate in 5
Purpose: We evaluated the influence of urodynamic factors on the establishment of bacteriuria, after deliberate intravesical inoculation with Escherichia coli. Materials and Methods: Nine women and 7 men with recurrent symptomatic urinary tract infections underwent intravesical injection of E. coli 83972. This strain had documented ability to persist in the urinary tract and it lacks expressed vir
(S)-Hydroxynitrile lyases from Hevea brasiliensis, Manihot esculenta, and Sorghum bicolor and (R)-hydroxynitrile lyase from Prunus amygdalus have been used as biocatalyst for the enantiospecific addition of hydrogen cyanide to aldehydes in organic solvents. The effects of the reaction parameters on the enzymatic reaction rate and product enantiomeric excess (e.e.) are presented. The reaction rate
A technique of continuous water activity control was used to examine the effects of water activity on enzyme catalysis in organic media. Esterification catalyzed by Rhizopus arrhizus lipase was preferably carried out at a water activity of 0.33, which resulted in both maximal initial reaction rate and a high yield. When Pseudomonas lipase was used as catalyst it was beneficial to start the reactio
Esterification of N-acetyl phenylalanine with ethanol catalyzed by immobilized αchymotrypsin (EC 3.4.21.1) was studied in various reaction media. The effect of reaction medium polarity on enzymatic activity as well as equilibrium yield was measured. The reaction rate increased with increasing amounts of added water, reaching an optimum corresponding to water saturation of the reaction medium. Furt
The ability of several electron acceptors to promote the Gluconobacter oxydans catalyzed oxidation of glycerol was investigated. p-Benzoquinone was the most effective electron acceptor. The reaction rate obtained with p-benzoquinone was higher than the maximal rate with the natural electron acceptor, oxygen, in all the oxidation reactions tested.
Models of baryon structure predict a small quadrupole deformation of the nucleon due to residual tensor forces between quarks or distortions from the pion cloud. Sensitivity to quark versus pion degrees of freedom occurs through the Q2 dependence of the magnetic (M1+), electric (E1+), and scalar (S1+) multipoles in the γ∗p→Δ+→pπ0 transition. We report new experimental values for the ratios E1+/M1+
We report the first results of the beam-spin asymmetry measured in the reaction →ep→epγ at a beam energy of 4.25 GeV. A large asymmetry with a sinφ modulation is observed, as predicted for the interference term of deeply virtual compton scattering (DVCS) and the Bethe-Heitler process. The amplitude of this modulation is α=0.202±0.028. In leading-order and leading-twist perturbative QCD, the α is d
Fundmental comprehension of light-induced processes in perovskites are still scarce. One active debate surrounds the influence of excess lead iodide (PbI2) on device performance, as well as optoelectronic properties, where both beneficial and detrimental traits have been reported. Here, we study its impact on charge carrier recombination kinetics by simultaneously acquiring the photoluminescence q
The last decade has seen an expansion in initiatives promoting the development of special sex services oriented to people with disabilities, which in Europe are increasingly labelled ‘sexual assistance’. These have become the object of political and media attention, and arguably call for a critical analysis incorporating both disability and sex workers’ rights perspectives. Based on an 18-month em
Summary: The longitudinal growth rates of the distal fibula were measured, using a roentgen stereophotogrammetric method, in 32 children treated for slipped capital femoral epiphysis and compared with growth rates in a series of normal children. The growth rates in patients were similar to the growth rates in normal children, in both boys and girls. However, at the time of slippage, 13 patients ha
The use of motor reactions including spinal motor mechanisms, such as tail-flick, hot plate test, and flexion reflexes, in research on pain and analgesia requires some precautions, and results should be interpreted with caution. Nocifensive specificity and analgesic selectivity cannot be established unequivocally by only comparing reflexes evoked by noxious stimuli with monosynaptic reflexes. Rath
