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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192335 sökträffar

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Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. This thesis aims to address this issue by studying

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The theme of ICIS 2013 in Milan is "Reshaping Society through Information Systems" (http://icis2013.aisnet.org/). One aspect of reshaping society that has been recently discussed in central Europe is that of social inclusion (http://ec.europa.eu/social/main.jsp?catId=750&langId=en). Yet, after decades of research and ambitious political programs, we still observe an imbalanced treatment toward

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The significant environmental impact of the current fossil fuel-based industry is a major concern for society. Consequently, various initiatives are being undertaken to establish a more sustainable industrial model. One example is via the transition from conventional fossil fuel refineries to biorefineries, where renewable raw materials are utilised. Amongst these raw materials, the use of lignoce

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This master’s thesis is performed in collaboration with the Research Institute of Sweden. The purpose of the study was to investigate food neophobia, or an aversion to trying new foods, in the Swedish population and see if it correlates with the country's low and undiversified seafood consumption. The topic of the study stems not only from consumers consuming less seafood than is recommended,

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Rural Germany is massively dependent on fossil fuel driven cars. But in many villages, socio-technical innovations have emerged to tackle this dependency. Electric carsharing, often organised in grassroots-settings, is one of them. For such innovations to spread and grow, different projects from across the country need intermediariesto connect them in networks, or share ideas, and experiences. Thi

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In 2017, the #MeToo movement sparked a massive reckoning with a vast continuum of sexual abuse. From the moment the U.S. actress Alyssa Milano pressed the button ‘post’ on Twitter and unleashed a flurry of responses, the landscape of sexual misconduct allegations changed forever. Through social media platforms, #MeToo has provided a platform for marginalized voices to be heard, fostering a sense o

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The topic of the research is the representation of European diversities in the French-German cultural channel ARTE, specifically in its collection of documentaries from the Magazine Show ‘Regards: European Stories’, henceforth ‘Re: European Stories’ (2023-2024). By investigating the ways in which multiple dimensions of diversity - religion, politics, gender, ethnicity, race, disability, class and

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The global food system is a cause of the worldwide poly-crisis in climate change and ecological decay. Ecological food systems have been emerging to contest the ruinous food production model. This thesis explores one branch of ecological food production: urban farming. Focused on the Swedish context, cases in Växjö, Malmö, and Göteborg were analyzed to examine how urban farms and involved agents n

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The transition towards sustainable rail transportation has positioned hydrogen as a promising alternative to traditional fossil fuels. This thesis focuses on the analysis of design for onboard and offboard hydrogen storage systems for light trains, which plays an important role in facilitating the adoption of hydrogen-powered rail vehicles. It explores state-of-the-art hydrogen storage technolo

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The 2011 UN Guiding Principles on Business and Human Rights (UNGPs) introduced human rights due diligence (HRDD) as a societal expectation to businesses to implement a new kind of due diligence risk management process to ‘know and show’ they respect human rights. Ten years later, mandatory human rights due diligence (mHRDD) legislation imposing a legal duty to carry out HRDD has become mainstream

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Transposable elements (TE) are parasitic genetic entities that have the ability to alter their position within a genome and have the potential to influence its functionality. Although TEs play beneficial roles in the evolution of their host, they are active in various human disorders including neurological diseases, where may contribute to the progress of the disease. Long Interspersed Nuclear Ele

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In the present thesis, the interaction between atoms in superposition states and attosecond pulses is studied from the microscopic to the macroscopic regime. Using a semi-classical framework, three different models have been explored in order to investigate attosecond light--matter interaction processes. The first model is a microscopic, single-atom model. Through using this model, the absorptio

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This paper studies whether the level of IPO underpricing is enforced by increased firm complexity. Evidence from a sample of 215 Swedish IPOs between 2010–2020 suggests that investor’s ex-ante uncertainty increases as issuing firms become increasingly complex. As a consequence, firms exhibiting complexity generally experience higher degrees of IPO underpricing. Moreover, we find support for our cl

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Pancreatic cancer (PC) is a severe disease where only 8% of the patients survive longer than five years. Chemotherapy is the standard treatment option for patients with PC, either in adjuvant or palliative setting, however only 15% of the tumors are resectable. The poor prognosis highlights the need to identify new prognostic biomarkers and novel treatment options to improve patient outcome. This

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In 2020, the German government introduced a legislation to phase-out coal mining and combustion by 2038. Expert reports state that this is too late for Germany to meet its obligations from the Paris Agreement. For many people in Lusatia, one of the three coal mining areas in Germany, even the 2038 coal-exit is happening too fast. They fear for their economic and personal future in the coal-mining

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The development of electrical circuit boards is increasing and the time spent in the development stage can be quite long. The thesis has tried to shorten the time spent developing new electrical circuit boards, by first finding a common denominator for efficiency losses in the development process and then implementing an example solution. The problem identified was the lack of attention towards pr

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High affinity antibodies of appropriate isotype are crucial for protection against pathogens and are generated within secondary lymphoid organs in structures called germinal centers (GC). Apart from affinity maturation, germinal centers also give rise to memory B cells and plasma cells, but how these fate decisions are regulated and what signals may be delivered by TFH cells is still unclear. Usin

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Medans världens fossila bränslereserver sinar har utvinningen av fossilgas genom hydraulisk spräckning, allmänt känt som fracking, vunnit mark internationellt. Parallellt med detta uppenbarar sig klimatförändringarnas katastrofala effekter och tiden är knapp för att ställa om global energiproduktion innan medeltemperaturen når så kallade ”tipping points”. Syftet med denna uppsats är att utforska d

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The economic crisis in Greece resulted in a change in residential heating fuels utilized, which in turn resulted in a change of air quality over Greater Athens Area. The aim of this study was to investigate the effects of economic crisis in air quality over Attica by examining the change in air pollutants’ concentrations before, during, and after the onset of the economic crisis in Greece and to a