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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192517 sökträffar

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The purpose of this research was to find how young women in Bangkok spend their money, especially in terms of fashion consumption in the new context of globalized consumer society. The research was conducted through general observations and interviews with designers and fashion shop owners in order to find out their views of fashion and consumption among the young women in the city as well as thro

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The purpose of the present study is to compare the use of three major conjunctions ?and?, ?or? and ?but? by Chinese (Hong Kong) and American university students. The study is also concerned with the position and functions of major conjunctions. Materials from three corpora are used with the help of a concordance for functional analysis, which may be applied to ELT material design and classroom met

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The conflict between the right to data protection and the right of access to documents is mirrored in the Regulations embodying these rights, as they appear to have conflicting end-goals. The two main conflicts are, first, between the Article 8 of Regulation 45/2001 and the Article 6(1) of Regulation 1049/2001, and second, between the Article 4(1)(b) of Regulation 45/2001 or the principle of purpo

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This thesis analyzes the way peace and justice interact within the latest Colombian peace process between 2012-2016. This process was the first attempts at ending hostilities between the government and the FARC-EP in a decade. This thesis is carried out as an idea analysis of three different material categories: joint material from peace-negotiations, and materials attributed to the government or

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Ecologists have long proposed that environments providing more energy can support more species, yet empirical evidence frequently contradicts this expectation. We argue that such inconsistencies result from confounding geographical influences that mask the true relationship between species richness and energy-related factors. Here, by comparing species richness across different climate conditions,

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In this second article in a series based on various analyses of data from the survey of the vascular flora of the province of Skåne, southern-most Sweden, completed 1987–2007, the geographic distribution of mean indicator values are mapped and discussed. The Ellenberg indicator values are applied and found to correlate well with actual conditions as far as light, temperature and soil reaction (pH)

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The development of new therapies for the treatment of type 2 diabetes requires robust, reproducible and well validated in vivo experimental systems. Mice provide the most ideal animal model for studies of potential therapies. Unlike larger animals, mice have a short gestational period, are genetically similar, often give birth to many offspring at once and can be housed as multiple groups in a sin

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Exocytosis is the mechanism by which a vesicle inside the cell fuses with the plasma membrane to release its contents into the extracellular environment. The process might sound trivial but reduced expression or mutations in genes involved can cause a variety of disease states. The exocytotic process is a necessary part of neurotransmitter release from the pre-synaptic side into the synaptic cleft

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Aims/hypothesis Type 2 diabetes is characterised by progressive loss of pancreatic beta cell mass and function. Therefore, it is of therapeutic interest to identify factors with the potential to improve beta cell proliferation and insulin secretion. Bone morphogenetic protein 4 (BMP4) expression is increased in diabetic animals and BMP4 reduces glucose-stimulated insulin secretion (GSIS). Here, we

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Recoverin a member of the neuronal calcium sensor (NCS) branch of the calmodulin superfamily, is expressed in retinal photoreceptor cells and serves as a calcium sensor in vision. Ca2+-induced conformational changes in recoverin cause extrusion of its covalently attached myristate (termed Ca2+-myristoyl switch) that promotes translocation of recoverin to disk membranes during phototransduction in

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Detailed knowledge on habitat requirements is a key to successful conservation actions. The marbled jewel beetle Poecilonota variolosa (Buprestidae) has a wide global distribution but populations are often scarce and typically fragmented. In Sweden it is monophagous on aspen Populus tremula and is classified as near threatened on the Swedish Red List due to its rapid population decline. This study

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Summary Data on species' demography are essential to detect changes in population size, identify drivers of population change, motivate conservation plans, or evaluate the effectiveness of management. The Arctic Skua Stercorarius parasiticus is a seabird with a circumpolar distribution, which is listed as Endangered on the International Union for Conservation of Nature (IUCN) European Red List, al

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AbstractBackgroundThe role of nutrient intake in celiac disease pathogenesis is poorly understood.ObjectiveTo examine whether longitudinal childhood intake of selected vitamins and minerals is associated with celiac disease autoimmunity (CDA, primary outcome) and celiac disease (secondary outcome) in genetically at-risk children.MethodsA total of 6,520 HLA-conferred at-risk children in the observa

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Ozonation is one of the most promising advanced oxidation processes to be implemented as quaternary treatment for the removal of micropollutants in wastewater treatment plants. However, there are some knowledge gaps that limit its implementation. First, the removal efficiency is not known for all pollutants, and second, knowledge about degradation byproducts is limited, as well as the toxicity of

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BACKGROUND: Sepsis-induced coagulopathy (SIC) is a scoring system developed for early detection of coagulopathy in sepsis and selection of patients for interventional studies. Our aim was to define the prevalence of SIC in a critically ill population and investigate if SIC at intensive care unit (ICU) admission is associated with morbidity and mortality.METHODS: Patients admitted with septic shock

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Background: We aim to examine the association between ultra-processed foods (UPF) consumption and cardiovascular disease (CVD) risk and to identify plasma proteins associated with UPF. Methods: This prospective cohort study included 26,369 participants from the Swedish Malmö Diet and Cancer Study, established in 1991–1996. Dietary intake was assessed using a modified diet history method, and UPF c

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Background: Cognitive deficits are common and disabling residual symptoms following major depressive disorder (MDD) and are related to increased risk of relapse. Residual cognitive deficits should thus be considered an important target for treatment. However, few have reported long-term outcomes of interventions targeting residual cognitive deficits. Objective: This study aimed to (1) investigate

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IntroductionThe interest in Para athletes’ health continues to increase. Still, there are few studies that have evaluated health parameters beyond injury and illness in this athlete population.ObjectiveTo assess: i) the weekly proportion of elite Para athletes reporting anxiety/depression, low sleep levels (≤7 hours) and pain over 52 weeks and; ii) and to explore whether these health parameters ar

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The lack of effective, scalable solutions for lifestyle treatment is a global clinical problem, causing severe morbidity and mortality. We developed a method for lifestyle treatment that promotes self-reflection and iterative behavioral change, provided as a digital tool, and evaluated its effect in 370 patients with type 2 diabetes (ClinicalTrials.gov identifier: NCT04691973). Users of the tool h