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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 192508 sökträffar

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Background: Retention of study participants in observational studies is essential to maintaining the representativeness of the population, minimizing selection bias, and assuring sufficient statistical power. The aim of this report is to describe the structures and strategies used to retain participants in The Environmental Determinants of Diabetes in the Young (TEDDY) Study, an observational stud

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Transit spectroscopy usually relies on the integration of one or several transits to achieve the signal-to-noise ratio (S/N) necessary to resolve spectral features. Consequently, high-S/N observations of exoplanet atmospheres, where we can forgo integration, are essential for disentangling the complex chemistry and dynamics beyond global trends. In this study, we combined two partial 4-UT transits

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The growth of III-V nanowires has attracted significant attention due to their superior electrical and optical properties, which are crucial for advanced optoelectronic devices such as lasers and photonic circuits. Since the 1960s, Au has beenextensively used as a catalyst for III-V nanowire growth, with substantial research conducted through both ex situ and in situ techniques. However, Au introd

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Powders are essential ingredients of chocolate. In particular for milk chocolate milk and whey powders are important, together with sucrose, lactose and cocoa solids. During processing to maintain a good flow of the molten chocolate mass, particles with hydrophilic surfaces, such as dairy powders and sugars, are coated with a surface-active compound. Only lecithin and polyglycerol polyricinoleate

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In Ostend, Rosa Barba presents Pillage of the Sea, 2021, a permanent sculpture. Barba has anchored an outsized cairn on the beach, imitating stones by pouring concrete in textile. The textile makes one think of the form of sandbags, with which Barba creates a type of imaginary barrier against the future rise in the sea level. Each stone symbolizes a city, the fate of which is threatened by climate

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Stem cells are unique, undifferentiated cells that have the ability to both replicate themselves and develop into specialized cell types. This dual capability makes them valuable in the development of regenerative medicine. Current development in stem cell research has widened their application in cell therapy, drug discovery, reproductive cloning in animals, and cell models for various diseases.

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Introduction: Anti–glomerular basement membrane (GBM) disease is caused by pathogenic antibodies usually targeting the noncollagenous domain of the α3 chain of type IV collagen and frequently presents as rapidly progressive glomerulonephritis and diffuse alveolar hemorrhage (DAH). Rapid reduction of these antibodies is imperative for kidney survival and the mainstay of therapy is the combination o

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AimsAdipose tissue distribution, metabolism, and expansion capacity exhibit notable sex- and depot-specific differences. Herein, we monitored adipocyte traits related to insulin responsiveness and glucose transport during adipose expansion in visceral and subcutaneous fat from male and female mice.Material and methodsAdipocytes were isolated from perigonadal and inguinal adipose tissue of chow-fed

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Quantum information science has leaped forward with the exploration of high-dimensional quantum systems, offering greater potential than traditional qubits in quantum communication and quantum computing. To advance the field of high-dimensional quantum technology, a significant effort is underway to progressively enhance the entanglement dimension between two particles. An alternative effective st

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One of the benefits often claimed for 'moving' the state closer to people through the institutional reforms of democratic decentralisation is an improvement in the inclusion of politically marginalised groups. Decentralisation promises to deliver both the closer physical presence of centres of government and the formalisation of practices of representation at the grassroots. These changes in turn

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The COVID-19 pandemic has affected the entire area of health care, including care provided to patients with mental health problems. Due to the stressful nature of the pandemic, the number of patients experiencing mental health problems, especially depression or anxiety, has increased. Even well-before the pandemic, Europe struggled with a lack of mental health care, which was especially caused by

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Although political governance guides education and research, there are options for researchers, educators and curators to act in the spirit of academic freedom. The deontological ethical guidelines stabilize the archaeological establishment no matter what kind of work. The utilitarian dimensions within archaeological research and higher education open up for critical thinking.Twisting and turning,

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Quantum information science has leaped forward with the exploration of high-dimensional quantum systems, offering greater potential than traditional qubits in quantum communication and quantum computing. To advance the field of high-dimensional quantum technology, a significant effort is underway to progressively enhance the entanglement dimension between two particles. An alternative effective st

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The overall environmental impact of a product is influenced by decisions made during product development, e.g. on alternative materials. Different tools exist on how to select materials. However they are seldom adapted to a company's needs. The research question of this thesis is dedicated to this issue: Designing a material selection tool for the product development process of an organisation

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Sex trade in China resurfaced with the economic reforms of Deng Xiaoping in 1978, and has since evolved to an industry of gigantic scale. This paper analyzes the prostitution in China in a social, economic, political, and historical context, with a special emphasis on Shanghai. The problem posed is how to strike a balance between the positive and negative effects of prostitution. The solution prop

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Botswana has been a stable democracy since independence. There is a wide-spread assumption that this is due to democratic elements in its traditional system, and the minimal colonial influence exerted by the British. This thesis examines the character of the traditional system and the effects of the colonial presence, with the aim to ascertain how democratic pre-independent Botswana actually was.

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This case study aims to analyse the contribution of the Information Sector to the success of the Lisbon Agenda. The Information Sector is here defined as covering the areas of information technology, telecommunications and digitised information (e.g. software, content). The observations made through primary sources and reports show that the Information Sector spreads the ability to deal with the t