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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 194658 sökträffar

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The European Union is often compared to other political systems in order to better understand its basic features and how they structure politics. This article argues that this focus on comparative politics instils a domestic bias into the study of the EU, which also ignores the impact of enlargement. To remedy this, a comparison is suggested between the order of the EU as a regional international

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The current research investigates the removal of endocrine disruptor compounds (EDC) in the absence and presence of organic matter in aqueous solution and natural water. In addition, the interactions of different fractions of natural organic matter (NOM) and fulvic acid (FA) in 17α-estradiol (EE2), 17β-estradiol (E2), estrone (E1) estriol (E3) and bisphenol A (BPA) were assessed. The interaction e

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PURPOSE: Autoantibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) define pre-clinical autoimmune thyroid disease (AITD) which can progress to either clinical hypo- or hyperthyroidism. We determined the age at seroconversion in children genetically at risk for type 1 diabetes.METHODS: TPOAb and TgAb seropositivity were determined in 5066 healthy children with HLA DR3 or DR4 containing

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BACKGROUND: Cell blocks (CBs) are widely used for biomarker analyses such as immunostaining. Although immunohistochemistry on formalin-fixed paraffin-embedded tissues is standardized, there are multiple preparation methods and fixatives for cytology. Our objective was to investigate the effect of different common fixatives on the immunoreactivity of pleural effusion CBs with metastatic lung adenoc

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De senaste årtiondena har samhället i stort präglats av digitalisering. Så också detaljhandeln, med en växande betydelse av digitala plattformar där människor gör sina vardagsinköp via dator, till alltmer även via mobilen. Avgörande för om människor faktiskt kan genomföra sina köp i detaljhandeln är betalningar. Betalningar har liksom detaljhandeln också blivit mer digitala, med en stadig minskninThis dissertation explores how and why certain payment methods are used in retail.Payment methods have changed in their form throughout history, and rapidly so in recent decades. Surprisingly, the treatment of payment in retail research appears detached from its purpose of use; i.e. purchasing products and services.Payment has a role to play in the digitalisation of society and is part of shaping

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Inconel 718 represents a large portion of high-temperature metals in key industries, where the machining-induced surface integrity is quite important. As the different grain size results in various densities of grain boundaries in the deformed area, the surface integrity can be significantly affected. This paper studies the effect of workpiece grain size on machining-induced surface integrity when

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Proof logging has long been the established method to certify correctness of Boolean satisfiability (SAT) solvers, but has only recently been introduced for SAT-based optimization (MaxSAT). The focus of this paper is solution-improving search (SIS), in which a SAT solver is iteratively queried for increasingly better solutions until an optimal one is found. A challenging aspect of modern SIS solv

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Our study aims to investigate the relationship between social participation and loneliness among Chinese older adults and examine how their views of social change moderate the strength of this relationship. The cross-sectional nationwide data from the China Longitudinal Aging Social Survey (CLASS) was used. Results show that increased online participation and community participation were associate

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At key moments in history, political understanding and action are irrevocably transformed. What makes such moments of transformation possible? This article examines the emergence of African nationalism in South Africa, following the multivocal appeal to African nationhood made by proto-nationalist leaders and intellectuals. In doing so I examine how new political imagination can reconfigure the st

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It is estimated that global anthropogenic carbon dioxide (CO2) emissions reduced by up to 12% at the start of 2020 compared to recent years due to the COVID-19 related downturn in economic activity. Despite the large decrease in CO2 emissions, no reduction in the trend in background atmospheric CO2 concentrations has been detected. So, how long would it take for sustained COVID-19 CO2 emission red

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Aims and objectives:This article investigates naturalistic acquisition of a second dialect (D2), comparing the global accent of speakers of Brazilian Portuguese (BP) exposed to European Portuguese (EP), either as children or as adults (early vs late bilectals). The focus is on the predicted advantage of an early age of onset of the D2, as well as possible crosslinguistic influence from the D2 onto

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Immunoglobulin κ promoters show sequence divergence but conserved function between different subgroups. Here we show that three separate 5' elements are required for synergistic stimulation of transcription with the decamer in a κ promoter. These sites are a 5' E-box, a 3' AT-rich region in the pentadecamer (pd) element, and the κ-Y element. Elf-1 is a novel κ-Y element ligand induced upon mitogen

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A statistical analysis has been done for the variation of the moment of inertia in pairs of rotational bands between odd-A and adjacent A - 1 even-even nuclei at normal deformation. A smooth distribution centered at small differences or no difference is obtained but apart from this, no special surplus of so-called identical bands is found. Furthermore, it is found that upsloping orbitals are predo

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This book is about how distinctions are drawn between civilians and combatants in modern warfare and how the legal principle of distinction depends on the technical means through which combatants make themselves visibly distinguishable from civilians. The author demonstrates that technologies of visualisation have always been part of the operation of the principle of distinction, arguing that the

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Measurements of the suppression and correlations of dijets is performed using 3 µ b − 1 of Xe+Xe data at s N N = 5.44 TeV collected with the ATLAS detector at the CERN Large Hadron Collider. Dijets with jets reconstructed using the R = 0.4 anti- k t algorithm are measured differentially in jet p T over the range of 32 to 398 GeV and the centrality of the collisions. Significant dijet momentum imba

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In this article, we investigate the rhetorical uses and media frames associated with the term polarisation in Swedish print media from 2010 to 2021. We first produce a qualitative and detailed assessment of a sample of 240 articles and then proceed to a computational (word2vec) analysis of all major Swedish newspaper articles including the term (N = 32,805). We find that the term has changed its r

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Anthropogenic stressors such as agricultural intensification, climate change, andincreased densities of non-native managed bees used for crop pollination arecontributing to bee declines. Understanding how and why bees have responded topast environmental changes is crucial for predicting future ones and enablingmitigation to maintain the functioning of both natural and agricultural ecosystems.The a

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Background: Obtaining functional sperm cells is the first step to treat infertility. With the ever-increasing trend in male infertility, clinicians require access to effective solutions that are able to single out the most viable spermatozoa, which would max out the chance for a successful pregnancy. The new generation techniques for sperm selection involve microfluidics, which offers laminar flow