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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 195819 sökträffar

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The method of using morselized compacted cancellous allografts for hip arthroplasty revision shows results that seem to differ dramatically from other kinds of allografting. In structural cancellous allografts, bone ingrowth usually is limited to 2 to 3 mm, whereas morselized compacted grafts seem to be remodeled totally in several cases, as judged by radiography. In the current study, impacted ca

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Aim Africa is identified by the Inter-governmental Panel on Climate Change (IPCC) as the least studied continent in terms of ecosystem dynamics and climate variability. The aim of this study was (1) to adapt the Lund-Postdam-Jena-GUESS (LPJ-GUESS) ecological modelling framework to Africa by providing new parameter values for tropical plant functional types (PFT), and (2) to assess the sensitivity

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An experimental investigation has been carried out to find the pressure difference of the process of steam condensation across the port to channel in plate heat exchangers. In the present study, low corrugation angle (30 degrees) plates have been used for different number of channels, namely, 10 and 80. The process steam entered at 1 bar with a small degree of superheat. Water has been used as the

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Stimulation around the superior cerebellar peduncle or within the deep cerebellar nuclei is known to inhibit the inferior olive with a very long latency. It has been suggested that this inhibition is mediated by the GABA-ergic nucleo-olivary pathway, but alternative explanations such as activation of an indirect excitatory pathway or a pathway via the red nucleus are possible. A long-latency inhib

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Background: Ratios of values of brachytherapy source strengths, as measured by hospitals and vendors, comprise constant differences as, e.g., systematic errors in ion chamber calibration factors and measurement setup. Such ratios therefore have the potential to reveal the systematic changes in routines or calibration services at either the hospital or the vendor laboratory, which could otherwise b

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Eggs of mallard ducks (Anas platyrhynchos) and ring-necked pheasants (Phasianus colchicus) were incubated in clutches arranged to stimulate embryos to hatch earlier or later than normal. This manipulation of hatching time was achieved by combining eggs of different age in the same clutch. To ensure hatching synchrony, embryos communicate with each other during the last stage of incubation, resulti

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Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain

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It has been suggested that speakers with an L1 with lexical tones may have an advantage when it comes to perceptually discriminating between different tones in another tone language (Kaan, Wayland, Bao & Barkley, 2007). Other studies in L2-learning show that this is not entirely the case (van Dommelen & Husby 2009, So & Best 2010). A model of typological pitch prominence (Schaefer &

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The life-history parameters of most living organisms are modified by fluctuations in environmental conditions. The impact of environmental autocorrelation on population persistence is well understood in single species systems. However, in multi-species communities the impact of stochasticity is complicated by the possibility of different species having differing intrinsic responses to the environm

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TRIM28 is a corepressor that mediates transcriptional silencing by establishing local heterochromatin. Here, we show that deletion of TRIM28 in neural progenitor cells (NPCs) results in high-level expression of two groups of endogenous retroviruses (ERVs): IAP1 and MMERVK10C. We find that NPCs use TRIM28-mediated histone modifications to dynamically regulate transcription and silencing of ERVs, wh

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Background Therapeutic hypothermia (TH) is a promising treatment of stroke, but limited data are available regarding the safety and effectiveness of cooling methodology. We investigated the safety of TH and compared the cooling capacity of two widely used cooling strategies endovascular and surface cooling. Methods COOLAID Oresund is a bicentre randomized trial in Copenhagen (Denmark) and Malmo (S

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The thermal stresses in a concrete bridge are affected by the surrounding climate. Varying temperature will produce movements which, if restrained, may induce stresses in the structure. To predict the thermal stresses in box cross-sections, FE simulations have been performed with extensive climatic input data to simulate the temperature and resulting stress fields in the hollow concrete arch of th

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Experimental work in turbid media has shown that transillumination images can be significantly improved by limiting light collection to a subset of photons which are minimally distorted by scattering. The literature details numerous schemes (commonly termed ballistic imaging), most often based on time-gating and/or spatially filtering the detected light. However, due to the complex nature of the d