Sökresultat

Filtyp

Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 194667 sökträffar

No title

In the Bas-Draa Inlier (Anti-Atlas, Morocco), the Paleoproterozoic basement which is cut by the Ediacaran Taourgha granite is also crosscut by numerous dykes of a variety of trends, mostly of uncertain age. Two doleritic dykes are dated by the ID-TIMS U-Pb method on baddeleyite and yield emplacement ages of 1381 +/- 8 Ma (MSWD = 0.84) and 1384 +/- 6 Ma (MSWD = 1.4) determined for a N135 degrees E

No title

Femtosecond and nanosecond photolysis of CH2I2 in acetonitrile at an excitation wavelength of 266-nm yield the ground-state CH2I-I isomer product in similar to70% quantum yield. High isomer formation quantum yields (> 70%) were measured also in n-hexane, dichloromethane, methanol, and ethanol using nanosecond photolysis. The CH2I-I product is formed biphasically within similar to15 ps after excita

No title

Purpose: To evaluate if preoperative assessment with A Quick Test of Cognitive Speed (AQT) could increase the accuracy of predicting delirium after cardiac surgery compared to Mini-Mental State Examination (MMSE), and examine if a composite of variables, including cognitive function and depressive symptoms, could be useful to predict delirium. Patients and Methods: Cardiac surgery was performed in

No title

Background and aim: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreparable scarring of lung tissue, with most patients succumbing rapidly after diagnosis. The mevalonate pathway, which is involved in the regulation of cell proliferation, survival, and motility, is targeted by the bisphosphonate zoledronic acid (ZA). The aim of this study was to assess the antifibroti

No title

Studies of the apportionment of human genetic variation have long established that most human variation is within population groups and that the additional variation between population groups is small but greatest when comparing different continental populations. These studies often used Wright's F(ST) that apportions the standardized variance in allele frequencies within and between population gr

No title

Aims/hypothesis: Rapid and adequate islet revascularisation and restoration of the islet–extracellular matrix (ECM) interaction are significant factors influencing islet survival and function of the transplanted islets in individuals with type 1 diabetes. Because the ECM encapsulating the islets is degraded during islet isolation, understanding the process of revascularisation and engraftment afte

No title

Wastewater treatment with activated sludge is the most common way of treating wastewater. The process relies on bacteria converting nutrients, BOD and COD into biomass, CO2 and N2. Even though the configuration of activated sludge processes and wastewater treatment plants varies there are common problems which are shared. Filamentous bulking sludge is one problem that is widespread and disturbs th

No title

Genetic factors play an important role in the pathogenesis of osteoporosis but the genes that determine susceptibility to poor bone health are defined incompletely. Previous work has shown that a polymorphism that affects an Spl binding site in the COLIA1 gene is associated with reduced bone mineral density (BMD) and an increased risk of osteoporotic fracture in several populations. Data from cros

No title

Five patients with Menière's disease and disabling vertigo were treated with two intratympanic instillations of gentamicin given at an interval of about 12 h. Although no further gentamicin treatment was given despite the absence of any discernible effects on the vestibular endorgan at that time, all patients developed vertigo and nystagmus beating toward the untreated ear within 3 to 5 days after

No title

Multitype branching processes have been employed to determine the stack algorithm computational distribution for one subtree. These results are extended here to the distribution of the number of computations in any finite number of subtrees. Starting from the computational distribution forK-1subsequent subtrees, a recurrent equation for the distribution forKsubsequent subtrees is determined.

No title

Chronic myeloid leukemia (CML) is a myeloproliferative disorder associated with the translocation t(9;22)(q34;q11) and progresses from a relatively indolent chronic phase (CP) to an accelerated phase (AP) and finally to the more aggressive blast crisis (BC). The general aim of this thesis was to identify and characterize genetic abnormalities occurring at disease progression of CML using molecular

No title

Skeletal development is heterogeneous. Throughout growth, bone size is more maturationally advanced than the mineral being accrued within its periosteal envelope; before puberty, appendicular growth is more rapid than axial growth; during puberty, appendicular growth slows and axial growth accelerates. We studied women with differing age of onset of anorexia nervosa to determine whether this tempo

No title

Using microdialysis, extracellular noradrenaline (NA) levels in the rat cerebral cortex were studied under isoflurane/N2O anaesthesia before, during and for 6 hours following 10 min of forebrain ischemia in a 2-vessel occlusion model. A microdialysis probe was introduced into the parietal cortex and dorsal hippocampus in anaesthetized rats and continuously perfused with Krebs-Ringerbicarbonate buf

No title

Sequence analysis of Candida rugosa lipase 1 (LIP1) predicts the presence of three N-linked glycosylation sites at asparagine 291, 314, 351. To investigate the relevance of sugar chains in the activation and stabilization of LIP1, we directed site mutagenesis to replace the above mentioned asparagine with glutamine residues. Comparison of the activity of mutants with that of the wild-type (wt) lip

No title

Imaging beta cells is a key step towards understanding islet transplantation. Although different imaging platforms for the recording of beta cell biology have been developed and utilized in vivo, they are limited in terms of allowing single cell resolution and continuous longitudinal recordings. Because of the transparency of the cornea, the anterior chamber of the eye (ACE) in mice is well suited

No title

Älska Skog educational competition (Gothenburg, Sweden)Gothenburg-based educational institute Universeum is running annual design competitions on forest topics for primary school pupils, starting in 2016. Based on various activities in which pupils gain knowledge about forest-related challenges and opportunities as well as forestry, they would design plans to deal with those problems. After a firs