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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 195610 sökträffar

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Achieving climate policy goals and addressing the challenges of energy security requires very significant efforts from many private and public actors to bring immature technologies to competitiveness. Algae-based biofuel production is an emerging industrial sector that has great promise with regards to many sustainability aspects but faces many challenges in order to attain any meaningful market p

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The EU has assumed ambitious targets and strategies for the promotion of renewable sources of energy (RES) binding to all its member states. This report examines the proposed EU-wide policy instrument designed to help achieve the targets on renewable electricity and heat - the trading of Guarantees of Origin (GO). It analyses the rise and fall of the GO trading proposal in the European policy-maki

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Detta arbete är inspirerat av två flitigt debatterade skeenden inom den transatlantiska konkurrensrättsliga arenan och mera specifikt inom ramen för en prisrelaterad vertikal begränsning känd som prisbindning. Denna begränsning, enkelt definierad, går ut på förbestämmandet av minimipriser eller fasta priser av en tillverkare i ett vertikalt distributionsavtal. Det första skeendet ägde rum i FörenThis thesis is inspired by two thoroughly debated developments in the competition/antitrust law transatlantic arena and more specifically in the field of a price-related vertical restraint known as resale price maintenance (RPM). This restraint, loosely defined, encompasses the predetermination of minimum or fixed retail prices by a manufacturer in a vertical distribution agreement. The first de

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Corporate Social Responsibility (CSR) requires an organisation to be responsible for “the impacts of its decisions and activities on society and the environment, through transparent and ethical behaviour that contributes to sustainable development” (ISO Central Secretariat, 2011, p. 26). Companies are voluntarily starting to implement CSR due to understanding the social need or wanting to improve

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Det terrestra ekosystemet absorberar cirka en tredjedel av de antropogena utsläppen varje år, vilket är en avgörande ekosystemtjänst som minskar ökningstakten av atmosfärisk koldioxid och bidrar till att mildra klimatförändringen. Observerade koncentrationer av atmosfäriskt koldioxid uppvisar en stor årlig variabilitet som främst anses vara orsakad av det terrestra ekosystemets respons på klimatföThe terrestrial ecosystem sequesters about one-third of anthropogenic emissions each year, thereby providing a critical ecosystem service that slows the rate of increase of atmospheric carbon dioxide and helps mitigate climate change. Observed atmospheric carbon dioxide concentrations exhibit a large inter-annual variability which is considered to be caused primarily by the response of the terrest

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Abstract in Finnish Inleding Dagen's biomedicinska utveckling bidrar till förbättrad livskvalitet för många människor. Det kan röra sig om nya läkemedel eller andra kliniska behandlingar med avgörande betydelse för en person's hälsotillstånd. Dessa medicinska möjligheter är emellertid inte helt oproblematiska. Ofta är stora ekonomiska kostnader förknippade, inte enbart med utvecklingsarbetet, men

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Mobile business intelligence (m-BI), an extension of business intelligence (BI), promises to support decision-making on the move. What is new and interesting about m-BI is the fact that users can access and analyse business information when needed independently of time and place on mobile devices such as smartphones and tablets. This is largely due to the mobile capabilities entailed in m-BI, such

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BACKGROUND Madagascar is the fourth biggest island and one of the poorest countries in the world, with more than 75 % of the 24 million inhabitants living under poverty line. The health care system in the country is under development, as well as the field of rehabilitation services and the area of prosthetic and orthotic services in specific. There is very limited published research concerning reh

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Urban pluvial flooding is a growing climate-related risk in Nordic cities, where short-duration rainfall extremes interact with aging drainage infrastructure and urban form. This study analyses 17 years (2006–2023) of property-level basement flooding reports from Trelleborg, a coastal municipality in southern Sweden, to identify empirical rainfall thresholds and infrastructural conditions associat

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Background Achievement of global health goals will require assessment of progress not only nationally but also for population subgroups. We aimed to assess how the magnitude of socioeconomic inequalities in health changes in relation to different rates of national progress in coverage of interventions for the health of mothers and children. Methods We assessed coverage in low-income and middle-inc

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The mechanisms underlying biphasic insulin secretion have not been completely elucidated. We compared the pattern of plasma insulin changes during hyperglycemic clamps in mice to that of glucose-induced insulin secretion and cytosolic calcium concentration ([Ca2+](c)) changes in perifused mouse islets. Anesthetized mice were infused with glucose to clamp blood glucose at 8.5 (baseline), 11.1, 16.7

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Mass spectrometry imaging (MSI) generates large volumetric data sets consisting of mass to charge ratio (m/z), ion current, and x,y coordinate location. A typical analysis can acquire a dataset comprising tens of thousands of ion signals at each of thousands of sampling locations. This dataset volume often serves the limited purpose of measuring the distribution of a small set of ions with known m

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The signal crayfish Pacifastacus leniusculus is an invasive species in Sweden, threatening the red-listed nobel crayfish Astacus astacus through spreading the crayfish plague. Time-to-event models can handle censored data on such introduced populations for which the state (successful or not) is only partially known at the last observation, but even though data on introduced populations most often

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Abstract Divergent natural selection is often thought to be the principal factor driving phenotypic differentiation between populations. We studied two ecotypes of the aquatic isopod Asellus aquaticus which have diverged in parallel in several Swedish lakes. In these lakes, isopods from reed belts along the shores colonized new stonewort stands in the centre of the lakes and rapid phenotypic chang

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Reliable performance evaluation of wastewater treatment plants (WWTPs) can be done by simulating the plant behavior over a wide range of influent disturbances, including series of rain events with different intensity and duration, seasonal temperature variations, holiday effects, etc. Such simulation-based WWTP performance evaluations are in practice limited by the long simulation time of the mech

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Financial assurance is increasingly seen as a means to ensure orderly, clean and lasting closure of mines. Broadly interpreted, "closure" requires leaving viable ecosystems on mining lands that are compatible with a healthy environment and with human activities, that have low hazard, and that encompass measures to prevent ongoing pollution from the site in the long-term. Financial assurance encomp

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In this work we describe a new preparation method for an esterolytic imprinted polymer with catalytic sites on the surface. A template was prepared by immobilizing a transition state analogue (phosphoramidic acid derivative) of an esterolytic reaction within porous silica particles. Polymerization within the pores was carried out using 4-vinylimidazole as a functional monomer and divinylbenzene as

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A method has been developed for establishing a "University Without Walls" for the purpose of studying the relationship between electrocardiographic estimation and magnetic resonance imaging measurements of myocardial infarct size. The research team includes faculty and students from 4 medical centers, with expertise extending from clinical to technical. Weekly interactive videoconferences provide