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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 194664 sökträffar

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High density lipoprotein (HDL) and its principal protein component Apolipoprotein A-I (ApoA-I) are commonly recognised for their anti-cardiovascular disease properties. Multiple studies have indicated that they also have important roles in the context of glycaemic control and diabetes. Low levels of HDL and ApoA-I have been linked to increased risk of diabetes development. Furthermore, it has been

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Den process där nya länder går med Europeiska unionen (EU) kallas utvidgning. Det har haft en central roll i unionens utveckling. Sedan grundandet har EU vuxit från sex till tjugosju medlemsländer, under totalt sju utvidgningsomgångar. För närvarande är fem länder kandidater för medlemskap: Montenegro, Serbien, Albanien, Nordmakedonien och Turkiet. Kosovo och Bosnien och Hercegovina är potentiellaEnlargement, the process whereby countries join the European Union (EU), has had a key role in the Union’s development. Since its founding, the EU has grown from six to twenty-seven Member States, in a total of seven enlargement rounds. Currently, five countries are candidates for membership: Montenegro, Serbia, Albania, North Macedonia and Turkey. Kosovo and Bosnia and Herzegovina are recognised

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This research focused on the media framing of the issue of protection and safeguarding of the Haenyeo community in Jeju Island, South Korea. The Haenyeo are a community of fisherwomen who free dive to harvest sea life and are representative of the matriarchal cultural tradition of Jeju Island. This study aimed to analyze how the issue is framed in regional media and explored the reasons portrayed

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Diet-related diseases kill millions of people every year and pose significant costs to the economy and society. In Sweden, this is an increasingly prevalent phenomenon. However, a healthy diet can prevent this. This thesis investigates what costs and benefits there are to adopting healthy eating habits and how these effects impact the Swedish economy. This thesis finds that the costs and benefits

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Popular science summary Ecosystem seasonality in climate models Climate change has a major effect on the timing, intensity and duration of seasonal events in Earth´s ecosystems. These changes may remain undetected when analyzing them on an annual scale, as current climate models usually do. Therefore it is necessary to investigate the impact of ecosystem seasonality on climate processes to impr

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The first part of this thesis investigates if probing control can be applied to glucose feeding of the bacteria Bacillus subtilis producing the enzyme xylanase. The experimental work reveals unexpected results, where growth and cell/glucose yield are significantly lower in the feed phase than in the batch phase of a fed-batch cultivation. The reason for this is still unclear, but some hypotheses a

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The purpose of this thesis is to take the temperature of social capital in four cities – Bologna, Modena, Reggio nell’Emilia, and Parma – in the historical region Emilia in Italy. Social capital, which has been described as ‘the key to making democracy work’ is conceptualized and decomposed into two key variables: trust and participation. Furthermore, the study consists of new empirical statistica

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This paper investigates the distribution of the tax burden of the value added tax, VAT, in Switzerland. The current Swiss VAT system overall is slightly progressive, putting a higher tax burden on the high-income households. The analysis of different household types yields similar results. The results depend crucially on the measurement base adopted. It is however argued that the tax ratio as a pr

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This thesis examines how innovation affects firm performance in the United States during the financial crisis in 2008. A difference-in-difference estimation combined with Coarsened Exact Matching is applied on a panel data set of 4,928 U.S. firms between 2004 and 2011. Two opposing theoretical frameworks concerning the outcome are used to state hypotheses regarding if innovative firms perform bett

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SpectraCure AB is a start-up company aiming at treating internal solid tumours such as prostate tumours with an innovative technology called ‘Interstitial Photodynamic Therapy’. This treatment requires the use of fibres to deliver the amount of light required to activate a drug injected to the patient which leads to the destruction of the tumours. This treatment is patient-based which means that t

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Oxidativ stress i celler är en bakomliggande faktor till många dödliga sjukdomar. Detta kan kroppen reglera till en viss del med olika proteiner. Ett av proteinerna är Alfa-1-mikroglobulin (A1M) som kan sänka oxidativ stress i kroppen genom att t.ex binda till fria radikaler och bidra till vävnadsreperation. A1M transkriberas tillsammans med ett annat protein, bikunin, som har anti-inflammatoriska

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Biofilms are intricate bacterial communities prevalent in diverse environments and rely on complex physiological adaptations and interactions to manifest community-intrinsic properties. The biofilm matrix itself is a major contributor to biofilm dynamics, as one of the mediators of the interactions within the biofilm, and it is composed of a diverse array of molecules. This project focuses on Sten

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Previous research has shown that conducting scientific research aimed at studying human behavior in a virtual environment in the context of safety is feasible. However, most applications of this kind are done with a primary focus on the visual aspects of the virtual environment. This study investigates if (a) a visual and auditory recreation of a real-world environment in Virtual Reality (VR) for

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This thesis delves into the construction and exhibition of national identity during the first decade of President Suharto's Indonesian rule, focused on its role in legitimising authoritarianist measures and enabling external interventions, with a particular focus on East Timor. Through a postcolonial perspective and employing a Critical Discourse Analysis, it explores how national identity was

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Landscapes fill a fundamental function of the human experience. The variance of these landscapes however, are vast, and arguably, so could the human experience of them and the ways they are expressed linguistically be as well. Of the few studies that so far has been conducted on this, none has focused on North America as a whole in a quantitative manner. This study aims to explore what systems lan

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This thesis explores how new ventures develop routines for using artificial intelligence (AI) in social media marketing. As AI tools become more accessible, many small companies begin using them without formal rules or training. The study focuses on small and medium-sized enterprises (SMEs) in the early stages of development and examines how AI use begins and spreads within teams. The research is

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Global post-industrial cities face the dual challenge of sustaining growth while repairing damaged ecosystems. Industrialization has left profound scars on both ecological networks and the urban fabric, demanding systematic spatial regeneration and environmental repair. Among these, abandoned brownfields hold unique potential: they offer opportunities to reshape urban structures, restore ecologica

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This thesis examines the Netherlands as a deviant case in the cooperation networks of the Council of the European Union. Drawing on seven waves of the Negotiations in the Council of the European Union dataset (2003-2021), it documents a trajectory more complex than the existing literature recognizes: a positive size-adjusted residual (overperformance) in every wave combined with a sustained declin

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Utvecklingen av autonoma fartyg (‘MASS’) innebär betydande utmaningar för det befintliga systemet för sjörättsligt ansvar. Culpabaserat ansvar och begreppet vårdslöshet är traditionellt uppbyggda kring bedömningen av mänskligt handlande, beslutsfattande och kontroll. Detta väcker frågor om huruvida vårdslöshet och culpa fortfarande är begreppsmässigt sammanhängande när operativa beslut fattas av aThe development of Maritime Autonomous Surface Ships (‘MASS’) presents significant challenges to the existing framework of maritime liability law. Fault-based liability and the concept of negligence are traditionally structured around the assessment of human conduct, decision-making and control. This raises the question of whether negligence and fault remain conceptually coherent where operational

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This thesis investigates if the recent decisions by the Commission on State aid in direct tax law are intruding on the EU Member States’ fiscal sovereignty. The author concludes that the Commission’s basic legal arguments of the reference system, being the corporate income tax system of the relevant Member States, as well as the arm’s length principle as a tool to assess selectivity in article 107