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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 194702 sökträffar

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BACKGROUND Madagascar is the fourth biggest island and one of the poorest countries in the world, with more than 75 % of the 24 million inhabitants living under poverty line. The health care system in the country is under development, as well as the field of rehabilitation services and the area of prosthetic and orthotic services in specific. There is very limited published research concerning reh

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The carbon isotope composition (δ13C) of seawater provides valuable insight on ocean circulation, air-sea exchange, the biological pump, and the global carbon cycle and is reflected by the δ13C of foraminifera tests. Here more than 1700 δ13C observations of the benthic foraminifera genus Cibicides from late Holocene sediments (δ13CCibnat) are compiled and compared with newly updated estimates of t

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Combining palaeontological and neontological data offers a unique opportunity to investigate the relative roles of biotic and abiotic controls of species diversification, and the importance of origination versus extinction in driving evolutionary dynamics. Ferns comprise a major terrestrial plant radiation with an extensive evolutionary history providing a wealth of modern and fossil data for mode

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Mineral weathering plays an important role in soil formation, long-term plant nutrition, and the global carbon cycle. The dissolution rate of most soil minerals is extremely slow. Nearly 100. years ago it was proposed that plants actively mine for nutrients locked in soil minerals. In more recent times the role of plant-associated mycorrhizal fungi has been emphasized. In this chapter we criticall

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Background: A family history of diabetes (FHD) is a strong predictor of diabetes risk, yet has rarely been investigated in latent autoimmune diabetes in adults (LADA). This study therefore investigated the risk of LADA and type 2 diabetes (T2D) in relation to FHD, taking into account the type of diabetes in relatives. Methods: Data from a population-based study were used, including incident cases

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Morphometric multivariate analysis has been performed based on 23 characters observed on 113 herbariumspecimens from throughout Fennoscandia. This demonstrates that four taxa can be recognised withinErigeron acris L. sensu lato, viz. E. acris L. subsp. acris, E. acris subsp. decoloratus (H. Lindb.) Hiitonen,E. acris subsp. droebachiensis (O. F. Müll.) Arcang. and E. acris subsp. politus (Fr.) H. L

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Pottiaceae subfam. Trichostomoideae in Scania, S Sweden – The members of Pottiaceae subfam. Trichostomoideae excluding Weissia spp. in the province of Skåne (Scania), southern-most Sweden, has been revised based on vouchers collected during the ongoing inventory of the bryophyte flora of the province. In addition, all available earlier records have been compiled and are presented for comparison (b

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OBJECTIVE Gastrointestinal adverse effects occur in 20–30% of patients with metformin-treated type 2 diabetes, leading to premature discontinuation in 5–10% of the cases. Gastrointestinal intolerance may reflect localized high concentrations of metformin in the gut. We hypothesized that reduced transport of metformin via the plasma membrane monoamine transporter (PMAT) and organic cation transport

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It is well recognized that the capacity of soils to sequester carbon (C) is strongly influenced by nitrogen (N) and phosphorus (P) availability because of the strong stoichiometric links between these biogeochemical cycles. Human disturbance (e.g., deposition, fertilization, and mining), has, and continue to have, caused large imbalances between the biogeochemical cycles and changing nutrient avai

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Hedgerows structure agricultural landscape worldwide but little is known on their soil communities. In the intensively managed agricultural landscapes of Ireland and the UK, hedgerows protect soil from degradation and are thought to provide a reservoir of soil biodiversity for the farmed fields. But hedgerows are currently threatened by emergent tree diseases spread with rising volumes of trade in

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The latitudinal diversity gradient (LDG) is one of Earth’s most iconic biodiversity patterns and still one of the most debated. Explanations for the LDG are often categorized into three broad pathways in which the diversity gradient is created by (1) differential diversification rates, (2) differential carrying capacities (ecological limits), or (3) differential time to accumulate species across l

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Urban spatial development is a crucial issue for spatial planning and urban governance, ultimately determining cities’ sustainability. While a set of spatial strategies to address urban development are progressively gaining international consensus, their actual applicability is still contested. An interesting test-bed is represented by the European Union (EU), where common spatial strategies have

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Temperature sums are widely used to predict the seasonal timing of yearly recurring biological events, such as flowering, budburst, and hatching. We use a classic energy allocation model for annual plants to compare a strategy for reproductive timing that follows a temperature sum rule (TSR) with a strategy that follows an optimal control rule (OCR) maximizing reproductive output. We show that the

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Massively parallel DNA sequencing opens up opportunities for bridging multiple temporal and spatial dimensions in biodiversity research, thanks to its efficiency to recover millions of nucleotide polymorphisms. Here, we identify the current status, discuss the main challenges, and look into future perspectives on biodiversity genomics focusing on insects, which arguably constitute the most diverse

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The evolution of industrial-era warming across the continents and oceans provides a context for future climate change and is important for determining climate sensitivity and the processes that control regional warming. Here we use post-ad 1500 palaeoclimate records to show that sustained industrial-era warming of the tropical oceans first developed during the mid-nineteenth century and was nearly

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ABSTRACT. For programs that aim to promote forest conservation and poverty alleviation, such as Reducing Emissions from Deforestation and Forest Degradation (REDD+), the participation of indigenous communities is essential to meet program goals. Using Ostrom's theory of collective action for common pool resource management, we evaluated the institutions governing indigenous participation in the Pr