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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 196120 sökträffar

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Abstract In line with inbreeding theory, genetic diversity at a set of molecular markers may explain variation in fitness-associated traits in partially inbred populations, and such associations will appear as 'genotype-fitness correlations'. An individual genetic diversity index specifically used for microsatellites is 'mean d(2)', i.e. the mean squared distance between alleles. The original hypo

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A high-resolution study of benthic foraminiferal assemblages was performed on a ca. eight metre long sediment core from Gullmar Fjord on the west coast of Sweden. The results of Pb-210- and AMS C-14-datings show that the record includes the two warmest climatic episodes of the last 1500 years: the Medieval Warm Period (MWP) and the recent warming of the 20th century. Both periods are known to be a

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Quinoline-3-carboxamides are currently in clinical development for treatment of both autoimmune disease and cancer. Carboxamides such as ABR-215757 (5757) have shown efficacy in several in vivo mouse models of human inflammatory autoimmune disease. Some microbial infections in mice cause GM-CSF dependent accumulation of dendritic cells expressing TNFα and inducible nitric oxide synthase (iNOS; Tip

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The unique flora and fauna of calcareous sandy grasslands is threatened by acidification, eutrofication and changed land use. Restoration experiments in such grasslands in southern Sweden, including deep and shallow soil perturbation, allowed us to examine the effects of pH and disturbance on the bryophyte flora. We also studied natural pH and disturbance gradients in order to compare the natural

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Environmental peacebuilding has emerged as an interdisciplinary field that integrates environmental governance with conflict resolution and post-conflict recovery. This chapter argues that this emerging field should be understood as a new paradigm in international law in two respects. First, it is a paradigm of legal ordering. In the absence of a single coherent regime for post-conflict environmen

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Background: Metastasis-directed stereotactic body radiotherapy (MD-SBRT) has shown promise in retrospective and phase II studies for oligometastatic hormone-sensitive prostate cancer. However, prospective randomized phase III data—particularly in newly diagnosed cases and in combination with androgen deprivation therapy and next-generation androgen receptor pathway inhibitors—are limited. The METR

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A key consideration in the design of a new industrial site is the spatial arrangement of units with respect to required safety distances. Safety distance requirements are intended to reduce the risk of hazardous events escalating from their origin to other units as well as to limit the damage to particularly vulnerable targets (e.g., control rooms), and are typically based on industrial standards

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Background: Older adults aging with long-term spinal cord injury (SCI) are insufficiently physically active to reach health benefits. However, little is known about their perceptions of physical activity (PA) and barriers and facilitators to their PA engagement.Objectives:To explore perceptions and experiences of engagement and participation in PA among older adults aging with long-term SCI.Method

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Celiac disease etiopathogenesis requires genetic predisposition and exposure to gluten, yet these factors alone are not sufficient. Larger longitudinal studies are needed to determine the role of time-varying infections and gut microorganisms. The aim was to design a celiac disease case-cohort longitudinal study using The Environmental Determinants of Diabetes in the Young (TEDDY) study. By age 3-

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Background: Japan lacks efficient assessment tools for occupational balance (OB) in people with mental illness (MI). Aims/objectives: We investigated the test–retest reliability and construct validity of a Japanese version of the Satisfaction with Daily Occupations and Occupational Balance (SDO-OB-J) for people with MI. Methods: SDO-OB-J interviews were conducted twice at a 2-week interval. Result

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Straw addition is a widely used agricultural practice to maintain soil fertility. However, its effects on soil organic carbon (SOC) and nutrient cycling are complex, with outcomes ranging from inhibition to stimulation of SOC mineralization via the priming effect. Freeze-thaw cycles are common disturbances in agroecosystems of high-altitude regions that are predicted to increase in frequency and s

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Over the past fifteen years, Rwanda has made significant progress in formalizing mining rights and the production processes of 3Ts minerals in its artisanal and small-scale mining (ASM) sector. However, labour relations remain largely unregulated. This study analyses ASM activities through the production process observations, document reviews, and interviews with key informants involved in the sec

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Objective: The aim of this study was to describe and assess changes in participants' experiences of everyday occupations after nature-based vocational rehabilitation (NBVR), to assess changes regarding symptoms of severe stress and the rate of return to work and possible association with experiencing the occupational value of everyday occupations. Methods: The NBVR was carried out by a transdiscip

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BACKGROUND: This study compares the high-frequency QRS components (HF-QRS) in patients with and without standard electrocardiogram (ECG) changes indicative of old myocardial infarction (MI). Previous studies have indicated that patients with an old MI differ in their HF-QRS compared with healthy subjects. The HF-QRS has been reported to be decreased during acute coronary occlusion and increased af

Protokoll bs 20151207

Bibl io tekss tyrel sen Närvarande Ledamöter Olov Sterner dekanus, naturvetenskapliga fakulteten, ordförande Samuel Byrskog prodekan, humanistiska och teologiska fakulteterna Gudrun Edgren professor, medicinska fakulteten Christofer Edling professor, samhällsvetenskapliga fakulteten ( -14:50) Tomas Hellström professor, Ekonomihögskolan Jan-Åke Nilsson professor, naturvetenskapliga fakulteten Per N

https://www.lub.lu.se/sites/lub.lu.se/files/protokoll_bs_20151207.pdf - 2026-10-05

Sustainability and global health study guide 2019

MESS52 – Sustainability and Global Health Sept. 3th – Oct. 31st 2019 1 Study Guide Sustainability and Global Health, 7.5 credits Course convenor and teacher: Dr. Sara Gabrielsson (sara.gabrielsson@lucsus.lu.se) Teachers: SG - Sara Gabrielsson, Assistant Professor, LUCSUS LK Louise Klintner, Dept. of Economics, LU YM- Yahia Mahmood, Associate Professor, Development Geography, LU KK- Karin Lundgren

https://www.lumes.lu.se/sites/lumes.lu.se/files/sustainability_and_global_health_study_guide_2019.pdf - 2026-10-05