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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 195610 sökträffar

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A DRIFT study of the adsorption and the (amm) oxidation of toluene was carried out at 150–300°C on a TiO2(B)-supported vanadia catalyst with a loading corresponding to 1.9 Mg V2O5 per m2 of the support surface area. In the absence of NH3 and gaseous oxygen, the adsorption of toluene at 150°C produces benzyl and benzoate intermediates. After one hour at the same temperature, further conversion of b

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Genetic and phenotypic variation in female response towards male mating attempts has been found in several laboratory studies, demonstrating sexually antagonistic co-evolution driven by mating costs on female fitness. Theoretical models suggest that the type and degree of genetic variation in female resistance could affect the evolutionary outcome of sexually antagonistic mating interactions, resu

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Members of the REST gene family characteristically have a transcription unit consisting of three exons. The first and the last exon are conserved among members, while the second exon--encoding almost all of the mature protein--differs considerably. The so far known REST genes are highly, and almost exclusively, expressed in the seminal vesicles. By sequence analysis we have now identified the gene

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A series of comparative studies is suggested, focused on perceptions of outrigger canoes, and aimed at an increased understanding of the relationship between social relations, biodiversity, and sustainable development in Oceanic societies on small islands and in coastal areas undergoing rapid cultural change. After a critique of the recent notion that canoe-building in Polynesia developed as a res

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Context: It is an enigma that agile projects can succeed ‘without requirements’ when weak requirements engineering is a known cause for project failures. While agile development projects often manage well without extensive requirements test cases are commonly viewed as requirements and detailed requirements are documented as test cases.Objective: We have investigated this agile practice of using t

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OBJECTIVE Plasma metabolites that distinguish isolated impaired glucose tolerance (iIGT) from isolated impaired fasting glucose (iIFG) may be useful biomarkers to predict IGT, a high-risk state for the development of type 2 diabetes. RESEARCH DESIGN AND METHODS Targeted metabolomics with 23 metabolites previously associated with dysglycemia was performed with fasting plasma samples from subjects w

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Fatigue performance under axisymmetric push-pull loading of a magnesium alloy Mg-6Zn-0.5Zr (ZK60) after processing by integrated extrusion and equal-channel angular pressing was investigated. Such processing was shown to nearly treble the endurance limit of the alloy, raising it to 160 MPa. It was established that the high-cycle fatigue performance of ZK60 is primarily controlled by dislocation su

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Allometry is a description of organismal growth. Historically, a simple power law has been used most widely to describe the rate of growth in phenotypic traits relative to the rate of growth in overall size. However, the validity of this standard practice has repeatedly been criticized. In an accompanying opinion piece, Packard reanalysed data from a recent study on brain-body ontogenetic allometr

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Non-exhaust wear emissions from disc brakes affect the air quality in cities throughout the world. These emissions come from the wear of the contact surfaces of both the pads and disc. The tribological and emissions performance of disc brakes strongly depend on the contact surface characteristics of the pads and discs. The surfaces of conventional pads are scorched by heating it to several hundred

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Bacillus Calmette–Guérin (BCG) vaccine against tuberculosis (TB) is recommended given at birth in TB-endemic areas. Currently, BCG vaccination programmes use “BCG vaccination coverage by 12 months of age” as the performance indicator. Previous studies suggest that BCG-vaccinated children, who develop a scar, have better overall survival compared with BCG-vaccinated children, who do not develop a s

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We present a new analytical equation of state (EOS), which correctly models high pressure theory and fits well to the experimental data of E-Fe, SiO2, Mg2SiO4, and the Earth. The cold part of the EOS is modeled after the Varpoly EOS. The thermal part is based on a new formalism of the Gruneisen parameter, which improves behavior from earlier models and bridges the gap between elasticity and thermo

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Aim: Head injury is the most common trauma occurring in syncope. We aimed to assess whether syncope as cause of head-trauma affects short-and long-term prognosis. Methods: From a database retrospective analysis of 97,014 individuals attending Emergency Department (ED), we selected data of patients with traumatic head injury including age, gender, injury mechanism, brain imaging, multiple traumas,

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The sulfur L-shell photoelectron spectrum of the carbon disulfide molecule has been studied using monochromated synchrotron radiation with a photon energy of 250 eV. The spectrum is atomic like, showing three major bands that can be associated with the sulfur (2p-1)2P3/2,12 and (2s-1)2S1/2 ionic states. A closer inspection shows that the 2P3/2 state is further split into two components separated b

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Importance: Accurate and up-to-date estimates on incidence, prevalence, mortality, and disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-based health care planning and resource allocation for these disorders. It appears that no such estimates have been reported at the state level for the US. Objective: To present burden estimates of major neurological d

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This contribution analyses the first decision by the Court of Justice of the European Union (CJEU) on the qualification and regulation of stand-alone software as medical devices. Referring to the facts of the case and the applicable EU regulatory framework, the Court specifically found that prescription support software may constitute a medical device. This would even be the case where the softwar