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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193313 sökträffar

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In this letter we apply the Generalized Method of Moments (GMM), widely used in econometrics, to receivers operating with imperfect channel state information (CSI) of singleinput-multiple-output (SIMO) block-fading channels where a single pilot symbol is used. The GMM results in the standard maximum ratio combining (MRC) receiver, but with an improved channel estimate. Although not our goal at the

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The paper explores perceptions during the early 20th century regarding the required and desired underpinnings of a post-imperial India—i.e. one in which both British India and the indirectly ruled Princely States were first, by the British, proposed and then, through the work of the Indian Constituent Assembly, made to constitute a federation. At the heart of the paper resides a query regarding In

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Summary: We examined cross-sectional associations of metabolic syndrome and its components with male bone turnover, density and structure. Greater bone mass in men with metabolic syndrome was related to their greater body mass, whereas hyperglycaemia, hypertriglyceridaemia or impaired insulin sensitivity were associated with lower bone turnover and relative bone mass deficits. Introduction: Metabo

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Background The familial risks of heart failure (HF) remain largely undetermined. This nationwide follow-up study aimed at determining risk of hospitalization for HF conferred by affected siblings. Methods and results Swedish Multi-generation Register data, with records of at least one full sibling available at start of follow-up, were linked to the Hospital Discharge Register data for 1987–2010. T

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The relation between use of sunscreens, different host factors and malignant melanoma was investigated in a population-based, matched case-control study of malignant melanoma in the South Swedish Health Care Region, which has the highest risk for melanoma in Sweden, between 1 July 1988 and 30 June 1990. In total, 400 melanoma patients and 640 healthy controls aged 15-75 years answered a comprehens

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Aims: To examine the relationship between plasma levels of the acute-phase proteins ceruloplasmin, alpha-1-antitrypsin, orosomucoid, haptoglobin and C-reactive protein (CRP), and incidence of diabetes in the population-based Malmö Diet and Cancer Study—Cardiovascular Cohort (MDCS-CC). Methods: The study population consists of 4246 participants (aged 46–67 years, 60.8 % women) with no previous hist

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This paper presents simulation results for a sliding-IF SiGe E-band transmitter circuit for the 81-86 GHz E-band. The circuit was designed in a SiGe process with fT = 200 GHz and uses a supply of 1.5 V. The low supply voltage eliminates the need for a dedicated transmitter voltage regulator. The carrier generation is based on a 28 GHz quadrature voltage oscillator (QVCO). Upconversion to 84 GHz is

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The screenplay written by Italian screenwriter and film director Massimo Franciosa in 1995 andfreely based on the short story Checchina’s virtue (1884) by Italian novelist and journalist MatildeSerao (1856-1927) is an example of those submedia ”designed especially to be transmediated”,according to Elleström (2014, 26). The transmediation never occurred however, since the filmnever came into being,

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In many mammals, the skin of the rhinarium includes a thick epidermal layer. The skin surface can be smooth but can also display a structure formed of domes, ridges, and polygonal areas: a dermatoglyphic or rhinoglyphic pattern. Each structure consists of an easily visible, large area of the epidermis. The abdominal epidermis may or may not have a dermatoglyphic pattern. The abdominal skin examine

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Unveiling the determinants for transferase and hydrolase activity in glycoside hydrolases would allow using their vast diversity for creating novel transglycosylases, thereby unlocking an extensive toolbox for carbohydrate chemists. Three different amino acid substitutions at position 220 of a GH1 β-glucosidase from Thermotoga neapolitana caused an increase of the ratio of transglycosylation to hy

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Recent studies have shown that a large proportion of patients classified as essential thrombocythemia (ET) actually have early primary prefibrotic myelofibrosis (prePMF), which implies an inferior prognosis as compared to patients being diagnosed with so-called genuine or true ET. According to theWorld Health Organization (WHO) 2008 classification, bone marrow histology is a major component in the

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Small angle X-ray (SAXS) and neutron scattering techniques were combined to study mixed complexes formed between micelles of the nonionic amphiphilic PEO-PPO-PEO copolymer (P123) and the anionic bile salt (NaGDC) in aqueous solution. The purpose was to investigate the structural parameters of the charged complexes, such as size and internal structure, as well as their interparticle interactions in

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Adenocarcinoma of the vermiform appendix is a rare disease that constitutes less than 0.5% of all gastrointestinal malignancies. A patient was admitted with abdominal discomfort and urinary frequency but no symptoms suggestive of enterovesical fistula, e.g. pneumaturia or urinary tract infection. She was diagnosed with adenocarcinoma of the appendix with a fistula to the urinary bladder.

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Mortality of patients with breast cancer is due overwhelmingly to metastatic spread of the disease. Although dissemination is an early event in breast cancer, extended periods of cancer cell dormancy can result in long latency of metastasis development. Deciphering the mechanisms underlying cancer cell dormancy and subsequent growth at the metastatic site would facilitate development of strategies