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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193232 sökträffar

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To increase the number of services and applications in the telecommunication networks a new service architecture has been proposed and specified. The consortia that initiated the new service architecture is called Parlay. Since then, there has been a continued development and 3GPP the standardization group for 3G networks, is now cooperating with Parlay. 3GPP and Parlay are together specifying the

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Customers of the packaging material industry are demanding shorter and more customized orders for each year. In many cases, the production has adapted to the new market demands. However, some finished goods warehouses are still adapted to the larger order sizes following a build-to-stock policy. In finished goods warehouses a shorter order sizes create problems, such as an increased amount of hand

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The aim of this study was to analyze the added utility of contrast administration for spine MRI in children with scoliosis. A retrospective review of 663 consecutive contrast-enhanced spine MRI performed in 319 patients as part of the work up of scoliosis in children 2-18 years with clinically suspected or known scoliosis over a seven year period. Those patients with known tumors (13 patients) bei

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We have compared the basic organization of the primary olfactory centre, the antennal lobe (AL), in 4 hemipteran species representing the 2 major lineages in this order. The Homoptera were represented by the psyllid Trioza apicalis and its aphid relatives the grain aphid Sitobion avenae Fabricius and the rose-grain aphid Metopolophium dirhodum Walker, whereas the Heteroptera were represented by th

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We present a simple correlation-corrected density functional treatment of dispersions containing macroions, where these are assumed to interact via screened Coulomb potentials, as given by Debye-Hückel theory. A straightforward mean-field description even fails to qualitatively capture important correlation effects displayed by such systems. However, if an effective, correlation-corrected potentia

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The thermophilic marine bacterium Rhodothermus marinus produces a modular family 10 xylanase (Xyn10A). It consists of two N-terminal family 4 carbohydrate binding modules (CBMs) followed by a domain of unknown function (D3), and a catalytic module (CM) flanked by a small fifth domain (D5) at its C-terminus. Several truncated mutants of the enzyme have been produced and characterised with respect t

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As today’s market forces the implementation of quality-of-service-enabled services spanned over multiple administrative domains, isolated and locally optimized interdomain routing decisions become increasingly inadequate. Instead, coordinated routing models are required together with joint optimization goals. Available papers and standardization documents focus on the description of technical mean

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Many food hoarding animals live in small groups structured by rank. The presence of conspecifics in the hoarding area increases the risk of losing stored supplies. The possibility of stealing from others depends on a forager's rank in the group. Highly ranked individuals can steal from subordinates and also protect their own caches. Since storing incurs both costs and benefits, the optimal hoardin

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Numerical simulations are used to compare the resolution and efficiency of 2D resistivity imaging surveys for 10 electrode arrays. The arrays analysed include pole-pole (PP), pole-dipole (PD), half-Wenner (HW), Wenner-alpha (WN), Schlumberger (SC), 'dipole-dipole (DD), Wenner-beta (WB), gamma-array (GM), multiple or moving gradient array (GD) and mid point-potential-referred measurement (MPR) arra

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Consider a risk Y-1 (x) depending on an observable covariate x which is the outcome of a random variable A with a known distribution, and consider a premium p(x) of the form p(x) = EY1 (x) + etap(1) (x). The corresponding adjustment coefficient gamma is the solution of E exp{gamma[Y-1(A) - p(A)]} = 1, and we characterize the rule for the loading premium p(1)((.)) which maximizes gamma subject to t

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IgA deficiency developed in a 2-year-old boy with aplastic anaemia who received a bone-marrow graft from his HLA-identical, 6-year-old, IgA-deficient sister. Southern blot analysis revealed the presence of alpha-genes in both children, thus suggesting a defect of lymphocyte stem-cell differentiation as a cause of IgA deficiency. Tissue typing showed homozygosity of HLA A1, B8, DR3, the haplotype a

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Very large collisions in the asteroid belt could lead temporarily to a substantial increase in the rate of impacts of meteorites on Earth. Orbital simulations predict that fragments from such events may arrive considerably faster than the typical transit times of meteorites falling today, because in some large impacts part of the debris is transferred directly into a resonant orbit with Jupiter(1,

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Background: Local pain at the site of intravenous (iv) injection of propofol remains a considerable problem in clinical anaesthesiology, and particularly so in infants. The aim of the present study was to compare the influence of two different emulsions of propofol on local pain following iv administration. Methods: Eighty adult patients (ASA I-II) scheduled for ear-nose-throat or plastic surgery

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The current interest in organizational culture, identity, image and reputation and in organizational discourse points towards the pressure on contemporary organizations to focus attention on the symbolic dimensions of their activities. The phenomenon of branding, while originally portrayed as a marketing tool, can also be understood as an exercise in management of meaning. Branding does not only i

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We present a physiologically stable porcine model designed for sequential assessments of pharmacological effects on mean hemispheric cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) at sustained normocapnia. The dynamic influence of continuously administered fentanyl (0.040 mg.kg-1.h-1 i.v.), nitrous oxide (70%) and pancuronium (0.30 mg.kg-1.h-1 i.v.) on these variables was