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Din sökning på "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" gav 193300 sökträffar

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Few other social technologies and institutions are more consequential to human societies than money. Yet money remains a deeply perplexing phenomenon. On the one hand, it is a pan-human system of valuation, but on the other, it is conventional and variable in its uses. While it is controversial if money instantiates a fully-fledged sign system, it is rife with semiotic capacities. To present an il

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Hemicelluloses account for 25-30% of total wood dry weight. Mannan-based polysaccharides are the major component of softwood hemicelluloses. They are characterized by their β-1,4-glycosidic linked backbone composed of mannose or a combination of mannose and glucose residues. The backbone can be substituted by α-1,6-linked galactose residues. β-mannanases cleave the internal β-1,4-glycosidic bonds

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The number of machine-type communications (MTC) devices is predicted to increase enormously in the near future, and this increase is expected to be accommodated by 5G. However, the Authentication and Key Agreement (AKA) mechanism used in the fourth generation of mobile telecommunications systems, EPS, may prove too inefficient for handling a large number of MTC devices simultaneously trying to con

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Background: Parkinson's disease (PD) is a chronic progressive disorder leading to increasing disability. While the symptoms and needs of patients in the early stages of their disease are well characterized, little information is available on patients in the late stage of the disease. Methods/design: The Care of Late-Stage Parkinsonism (CLaSP) study is a longitudinal, multicenter, prospective cohor

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Blockchain, the technology underlying bitcoin, is an emerging financial technology (FinTech) that is poised to have strategic impacts on organizations. Because it is a new phenomenon, there are few studies on blockchain, and those studies have focused mainly on the technology's potential impacts, whereas how to effectively implement it in an organization remains unknown. Our study intends to fill

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The structure and dynamics of a turbulent partially premixed methane/air flame in a conical burner were investigated using laser diagnostics and large-eddy simulations (LES). The flame structure inside the cone was charecterized in detail using LES based on a two-scalar flamelet model, with the mixture fraction for the mixing field and level-set G-function for the partially premixed flame front pr

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Background: Limited data exist of tracking and changes in accelerometer-measured physical activity in children. Methods: Physical activity was assessed by accelerometers for 4 days in 167 children (boys, n = 90; girls n = 77) age 9.8 ± 0.6 years. Follow-up measurement was made 2.0 ± 0.1 yrs later (range 1.9-2.1 yrs). General physical activity (GPA) was defined as mean count/minute. Minutes of inac

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In this paper, we investigate the impact of spatial coupling on the thresholds of turbo-like codes. Parallel concatenated and serially concatenated convolutional codes as well as braided convolutional codes (BCCs) are compared by means of an exact density evolution (DE) analysis for the binary erasure channel (BEC). We propose two extensions of the original BCC ensemble to improve its threshold an

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Popular Abstract in Swedish Läkares nattjour innebär långa arbetspass, höga krav, stress och sömnbrist. I dagens läge liknar nattjouren ofta ett nattskift med begränsade möjligheter till vila under arbetspasset. Skiftarbete med nattskift har i många undersökningar visats ge ökad risk för bland annat hjärtinfarkt och diabetes, samt även ha en negativ inverkan på välbefinnande och sömn. Samtliga desAbstract Physicians’ work on night-call entails long and stressful working hours with high demands and disrupted sleep. Incomplete recovery is considered to be the most important link between acute physiological stress reactions, shift work and chronic health effects. Mental and physiological activation naturally accompanies night-call duty, but the crucial issue, from a health perspective, is wh

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This paper presents a computerized grammar which can analyze and generate a sample of pedagogical Chinese sentences, in particular those mentioned in the textbook Kinesiska är inte svårt (‘Chinese is not difficult’) by Göran Malmqvist 1974. Equivalent grammars for English and Swedish have also been constructed allowing translation between the three languages. The grammar model used is the Swetra g

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Carotid endarterectomy (CEA) is a standardized surgical procedure and is the third most common vascular surgical procedure in Sweden. To improve the quality of pre- and postoperative care for patients undergoing elective CEA, a standardized care plan (SCP) was developed and implemented during Spring of 2007 at a vascular clinic in Sweden. In order to spread light on obstacles and possibilities in

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Specific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim of the present study was to investigat

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4-α-Glucanotransferase (GTase) enzymes (EC 2.4.1.25) modulate the size of α-glucans by cleaving and reforming α-1,4 glycosidic bonds in α-glucans, an essential process in starch and glycogen metabolism in plants and microorganisms. The glycoside hydrolase family 57 enzyme (GTase57) studied in the current work catalyzes both disproportionation and cyclization reactions. Amylose was converted into c

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Purpose: This study was intended to evaluate a multi-professional health-promoting and disease-preventive intervention organized as multi-professional senior group meetings, which addressed home-dwelling, independently living, cognitively intact elderly persons (80 +/-), by exploring the participants' experiences of the intervention. Method: The focus group methodology was used to interview a tota

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Active Brownian particles (ABPs), when subject to purely repulsive interactions, are known to undergo activity-induced phase separation broadly resembling an equilibrium (attraction-induced) gas-liquid coexistence. Here we present an accurate continuum theory for the dynamics of phase-separating ABPs, derived by direct coarse-graining, capturing leading-order density gradient terms alongside an ef