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Objective: To find out whether the biological marker, carbohydrate deficient transferrin (CDT), was helpful in the detection of alcoholic patients in a surgical unit. Design: Prospective open study. Setting: Teaching hospital, Denmark. Subjects: 286 men and 248 women admitted to the department of surgical gastroenterology between March and July 1996. Main outcome measures: Specific interview about

Migraines constitute a common neurological and headache disorder affecting around 15% of the world’s population. In addition to other mechanisms, neurogenic neuroinflammation has been proposed to play a part in migraine chronification, which includes peripheral and central sensitization. There is therefore considerable evidence suggesting that inflammation in the intracranial meninges could be a k

Preindustrial social mobility is still primarily understudied in present times, and most early-industrial social mobility research has focused strictly on occupational mobility, not fully capturing the substantial socioeconomic disparities within occupational groups that presumably always existed. In this study, we contribute to the literature by estimating long-term trends in intergenerational so

The categories and concepts in the existing official land-use maps have been under improvements over recent years; however, this study from Nordland, northern Norway, shows that they continue to pose several dilemmas when aiming to better capture the impacts of multiple land uses on reindeer herding. While these developments have done much to better communicate the presence of reindeer herding to

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite nu

A new neutron activation analysis system is currently being designed at Lund University. The design incorporates a compact accelerator driven neutron source, based on a 3 MV Pelletron accelerator and a pneumatic sample conveyor to transport samples from the neutron source to a measurement station consisting of an array of high-purity Ge γ-ray detectors. A prototype for this new station is currentl

BACKGROUND: Proteomic profiling could potentially disclose new pathophysiological pathways for cardiovascular diseases (CVD) and improve prediction at the individual level. We therefore aimed to study the plasma protein profile associated with the incidence of different CVDs. METHODS: Plasma levels of 245 proteins suspected to be linked to CVD or metabolism were measured in 4 Swedish prospective p

BackgroundFew studies synthesising knowledge about meaningful occupation are available. Meta-ethnography allows the synthesising of a variety of empirical findings and translational knowledge may be developed.AimInvestigate how individuals from diverse cultures and contexts experience meaningful occupation as described in qualitative research, applying meta-ethnographic approach.Material and metho

Objective: To examine associations between body mass index (BMI) in early pregnancy and gestational weight gain (GWG) with cardiovascular health in middle age using the ‘Life's Essential 8’ (LE8) concept of the American Heart Association (AHA). Design: Population-based cohort study. Setting: Swedish CardioPulmonary bioImage Study (SCAPIS). Population: A total of 8871 women from SCAPIS were include

This article suggests that the priestly features of John’s Christology merit further exploration, and highlights several priestly elements of the Fourth Gospel’s presentation of Jesus based on three Qumran texts: 1QS, 1QSa and 1QSb. It argues that there were at least three key characteristics of the Zadokite priesthood at Qumran that find correspondences with the activities of Jesus in John’s Gosp

Observed FeO/MgO ratios in the Moon and Earth are inconsistent with simulations done with a single homogeneous silicate layer. In this paper we use a newly developed equation of state to perform smoothed particle hydrodynamics simulations on the lunar-forming impact, testing the effect of a primordial magma ocean on Earth. This is investigated using the impact parameters of both the canonical case

OBJECTIVE: It was shown by genomic profiling that despite no detectable chromosomal abnormalities a proportion of children with pre-B acute lymphoblastic leukemia harbors copy number alterations (CNA) of genes playing role in B-cell development and function. The aim of the study was to determine the frequency of CNA in pediatric acute lymphoblastic leukemia and correlate these findings with clinic

Background: The aim of this study was to examine the incidence, risk factors, and outcomes of patients with acute kidney injury (AKI) after surgery for acute type A aortic dissection (ATAAD) using the Nordic Consortium for Acute Type A Aortic Dissection registry. Methods: Patients who underwent ATAAD surgery at 8 Nordic centers from 2005 to 2014 were analyzed for AKI according to the RIFLE criteri

BACKGROUND: A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process.METHOD: Seventy-six patients (bone-, cardiac-

MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate gene expression by binding to the 3' untranslated regions (UTR) of target genes. Aberrant expression of miRNAs can lead to disease, including cancer. Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Among several factors, differential expression of miRNA can have serious consequ

In recent decades, information technology has enjoyed an ever-increasing degree of influence upon society. The use of technology has proliferated, bleeding into all human activities, and now extends into the most private activities of individuals. Unfortunately the perpetrators of serious crimes have not missed the revolution. Technology has marked off many working terrains including that of serio

Recent experimental studies show that oppositely charged proteins can self-assemble to form seemingly stable microspheres in aqueous salt solutions. We here use parallel tempering Monte Carlo simulations to study protein phase separation of lysozyme/alpha-lactalbumin mixtures and show that anisotropic electrostatic interactions are important for driving protein self-assembly. In both dilute and co