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With increasing age, human skeletal muscles gradually decrease in volume, mainly due to a reduced number of motor units and muscle fibers, and a reduced size of type 2 fibers. As a result, progressive weakening and impaired mobility occur. High-resistance strength training is beneficial, even in the very old, and could possibly reverse some of the detrimental effects of age-related weakness. The i
Inner-sphere reorganization energies have been calculated for a number of models of six-coordinate iron porphyrins (with varying axial ligands), using the density functional B3LYP method. If the axial ligands are uncharged, the reorganization energy is very low, 5-9 kJ/mol. If one of the axial ligands is charged, the reorganization energy is higher, 20-47 kJ/mol, but such sites are normally not us
Interactions between antioxidant-impregnated low-density polyethylene (LDPE) and polypropylene (PP), and oxygen-sensitive foods have been investigated. BHT and a-tocopherol are two antioxidants commonly used in both foods and polymers. In general, BHT was rapidly lost from LDPE film in contact with various foodstuffs. a-Tocopherol was completely retained in PP film, but some losses, although less
The transcriptional events that control T cell tolerance are still poorly understood. To investigate why tolerant T cells fail to produce interleukin (IL)-2, we analyzed the regulation of NFkappaB-mediated transcription in CD4(+) T cells after tolerance induction in vivo. We demonstrate that a predominance of p50-p50 homodimers binding to the IL-2 promoter kappaB site in tolerant T cells correlate
The link between population mobility and environmental change is fundamental for our understanding of how future global environmental changes will affect our societies, and also how the increased mobility will change our role in the Earth system. Climate change has been predicted as a major cause of human migration, both voluntary and forced, through for example increased storm and drought frequen
Many Gram-positive bacteria express surface proteins that bind human plasma proteins. These bacterial proteins, and derivatives of them, are of interest for analysis of bacterial pathogenesis and as immunochemical tools. Well-characterized examples include the IgG-binding reagents staphylococcal protein A and streptococcal protein G, and the recently described streptococcal IgA-binding peptide Sap
Background: Accumulating evidence suggests that individual circulating saturated fatty acids (SFAs) are heterogeneous in their associations with cardio-metabolic diseases, but evidence about associations of SFAs with metabolic markers of different pathogenic pathways is limited. We aimed to examine the associations between plasma phospholipid SFAs and the metabolic markers of lipid, hepatic, glyca
Background: Dietary management of phenylketonuria (PKU) focuses on restricting phenylalanine (Phe) intake. The European PKU guidelines and the PKU Dietary Handbook recommend a simplified PKU diet, allowing unrestricted consumption of many low-Phe foods, called free foods. While this approach may reduce the treatment burden for patients, its implementation varies. This study investigated practi
Kursanalys Klimatförändringen, vetenskap och samhälle MVEN15 Kursanalys: Klimatförändringen, vetenskap och samhälle, MVEN15 Höstterminen 2020 A. Statistik Antal studenter: 31 Betyg: VG: 18, G: 13 B. Utvärdering Sammanfattning av kursutvärderingen Studenterna var i det stora hela nöjda med kursen (alla 3 eller högre, 16 av 21 4 eller högre). Kursen anses relevant för utbildningen (18 av 20 4 eller
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-04/Kursrapport%20MVEN15%20Ht%202020.pdf - 2026-07-09
June Master’s seminar round 2021, NGEM01 Time Student Zoom link Title Supervisor Opponent Committee Fri, Jun 4, 10.00 (sharp) – 12.00 Nicolas Tarasewicz https://uws.zoom.us/j/8498878 5433?pwd=REh6MzA2Vjcxc2 wzN29nMndQRGNGQT09 Expressing ecosystem model output and Swedish forestry goals with composite indicators Anna Maria Jönsson Johanna Asch Ben Smith, Alexandra Pongrácz Fri, Jun 4, 13.00 (sharp)
https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/2021-05/June%202021%20master%20seminars.pdf - 2026-07-09
Superantigens (SAgs) are bacterial enterotoxins produced by Staphylococcus aureus. Staphylococcal enterotoxin type A (SEA), a staphylococcal superantigen, has been shown to bind to the cytokine signalling receptor glycoprotein 130 (gp130). The structural details, as well as the exact physiological role of this interaction, remain unclear. Here, we describe the structural details of the SEA–gp130 c
This report relates to GIROD WP1 – “Development of a calculation model”. WP1 consists of four sub-WPs: 1.1 “Theoretical work”, 1.2 “Bond line tests”, 1.3 “Tests for calibration” and 1.4 “Calibration of model”.In WP1.1 theoretical models for rational prediction of pull out strength have been developed. The models include a very simple ideal plastic model, a linear elastic fracture mechanics model,
