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Several studies have presented data on the efficacy and tolerability of trastuzumab within clinical trials. As a minority of patients is included in these trials, we undertook this retrospective study to describe trastuzumab therapy in clinical routine and its tolerability. We reviewed the medical records of the first 48 patients in Sweden who received treatment with trastuzumab on a named patient
Hittills har över 50 miljoner ton e-avfall genererats globalt (World Economic Forum, 2019), vilket väcker frågan om den cirkulära ekonomins roll i kampen mot klimatförändringarna (Ellen MacArthur Foundation, 2021). I detta examensarbete undersöks möjligheterna för Axis Communications att införa ett system i USA för att ta tillbaka produkter som tagits ur bruk och återvinna dem. Inom detta område So far, over 50 million tonnes of e-waste have been generated globally (World Economic Forum, 2019), raising the question of the role of circular economy in combating climate change (Ellen MacArthur Foundation, 2021). This thesis explores the opportunities for Axis Communications to introduce a take back system for recycling decommissioned products in the US. Within this scope, several areas are
Genom att studera några av Sveriges just nu största intresseorganisationer och forskarnätverk för främjande av samhällsentreprenörskap, vill författarna skapa en nulägesanalys av området i Sverige - samt utmaningar att beakta för områdets framtida utveckling. Då uppsatsen har ett beskrivande syfte kring ett ämne som till vissa delar är outforskat i en svensk kontext, har en kombination av deskripThrough the study of some of Sweden´s at present largest associations and networks for the support of social entrepreneurship, the authors seek to establish a situation analysis over the Swedish field – as well as challenges to be considered for the future development of the field. While this paper aims at a descriptive purpose on a partly unexplored topic in a Swedish context, a combination of a
Exposure to some polycyclic aromatic hydrocarbons (PAH) increases the risk of cancer and is common, particularly for workers in occupations such as chimney sweeping. In exposed workers, screening of early cancer-related markers provides important information to identify individuals at risk. Here, we aimed to elucidate the associations between PAH exposure and serum levels of cancer-related protein
This study focuses on drivers for changing urban flood risk. We suggest a framework for guiding climate change adaptation action concerning flood risk and manageability in cities. The identified key drivers of changing flood hazard and vulnerability are used to provide an overview of each driver's impact on flood risk and manageability at the city level. We find that identified drivers for urban f
The European species of Euplectrus Westwood are comprehensively treated for the first time, using a combination of morphological and DNA data (CO1, the barcode). Ten species are included, seven already described: E. bicolor (Swederus), E. flavipes (Fonscolombe), E. intactus Walker, E. liparidis Ferrière, E. maculiventris Westwood, E. nigriceps Ferrière, E. phthorimaeae Ferrière, and three new spec
The primary aim of this study was to determine whether an increase in DLQI score can predict an eczema flare up and thus a need for treatment escalation/physician appointment. The secondary aim was to explore variations in DLQI over time.
Here we present an inverse analyses approach to determining the two-phase moisture transport properties relevant to concrete durability modeling. The purposed moisture transport model was based on a continuum approach with two truly separate equations for the liquid and gas phase being connected by the sorption kinetics. The moisture properties of ten binder-systems containing fly ash, calcined cl
Consumer goods manufacturers aiming to reduce the environmental impact associated with their products commonly pursue incremental change strategies, but more radical approaches may be required if we are to address the challenges of sustainable consumption. One strategy to realize step change reductions is to prepare a portfolio of innovations providing different levels of impact reduction in excha
AbstractThe overall aim of this thesis was threefold; first, to explore resources associated with work-life balance (WLB), with a focus on the work and private lives of human service employees. Second, to develop a workplace health promotion (WHP) intervention with a WLB focus. Third, to explore the participants’ experiences of the developed WHP intervention done in the workplace. A mixed method a
INTRODUCTION: The EUROpean Bone Over 40 Sarcoma Study (EURO-B.O.S.S.) was the first prospective international study for patients 41-65 years old with high-grade bone sarcoma treated with an intensive chemotherapy regimen derived from protocols for younger patients with high-grade skeletal osteosarcoma.METHODS: Chemotherapy based on doxorubicin, cisplatin, ifosfamide, and methotrexate was suggested
Purpose: The purpose of this paper is to identify the impact of enterprise systems (ESs), in particular radio frequency identification (RFID) and enterprise resource planning (ERP) systems, on supply chain management (SCM). The results of this conceptual paper demonstrate that ERP and RFID systems contribute to SCM by improving supply chain integration. Supply chain integration occurs to facilitat
This introduction develops a theoretical framework for understanding authoritarian backsliding against the backdrop of existing historical and European socio-legal scholarship. It introduces a number of key distinctions to better understand socio-legal variance among autocratisation. Specifically, it highlights the distinction between authoritarian backsliding and complete breakdown of judicial in
Motoric eating difficulties affecting the ability to eat according to established norms may result in loss of autonomy, reduced food intake and decreased social interaction. Finger food meals may affect the ability to eat independently and were therefore compared to regular meals for older adults >65 years with major motoric eating difficulties. In this pilot study the screening instrument MEOF-II
The relationship between the evolutionary dynamics observed in contemporary populations (microevolution) and evolution on timescales of millions of years (macroevolution) has been a topic of considerable debate. Historically, this debate centers on inconsistencies between microevolutionary processes and macroevolutionary patterns. Here, we characterize a striking exception: emerging evidence indic
Background: Home care underwent abrupt adaptations to handle the COVID-19 pandemic including an accelerated digitalization. While some research exists regarding the working conditions for home care personnel during the COVID-19 pandemic, few studies exist on the effect of everyday technology use in home care during the pandemic. The aim of this study was to investigate how digital technologies, in
Background: It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of UPFs with the risk of multimorbidity defined as the co-occurrence of at least two chronic diseases in an individual among first cancer at any site, cardiovascular disease, and type 2 diabetes.
